A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

YanPing Yu - Top 30 Publications

Influence of vitreomacular interface on anti-vascular endothelial growth factor treatment outcomes in neovascular age-related macular degeneration: A MOOSE-compliant meta-analysis.

The aim of the study was to evaluate the influence of vitreomacular interface configuration on treatment outcomes after intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapy for neovascular age-related macular degeneration (AMD).The Pubmed, Embase, and Cochrane Central Register of Controlled Trials databases were searched to identify relevant prospective or retrospective studies that evaluate the influence of vitreomacular adhesion (VMA) or vitreomacular traction (VMT) on functional and anatomical outcomes in neovascular AMD patients treated with anti-VEGF agents. The outcome measures were the mean change in best corrected visual acuity (BCVA) from baseline, the mean change in central macular thickness (CMT) from baseline, and the mean injection numbers of anti-VEGF treatment from baseline.In total, 9 studies were selected for this meta-analysis, including 2156 eyes (404 eyes in the VMA/VMT group and 1752 eyes in the non-VMA/VMT group). In neovascular AMD patients treated with anti-VEGF agents, the VMA/VMT group was associated with poorer visual acuity gains and CMT reductions at 1 year (WMD [95% CI], -6.17 [-11.91, -0.43] early treatment diabetic retinopathy study (ETDRS) letters, P = .04; WMD [95% CI], 22.19 [2.01, 42.38] μm, P = .03, respectively). There was no significant difference between 2 groups in the mean BCVA change and the CMT change over 2 years (WMD [95% CI], -5.59 [-21.19, 10.01] ETDRS letters, P = .48; WMD [95% CI], 6.56 [-24.78, 37.90] μm, P = .68, respectively). There was no significant difference in the mean injection numbers between 2 groups at 1 year (WMD [95% CI], 0.36 [-0.19, 0.90], P = .21), whereas the VMA/VMT group had a significantly higher mean injection numbers over 2 years (WMD [95% CI], 1.14 [0.11, 2.16], P = .03).The limited evidence suggests that vitreomacular interface configuration have a significant influence on the visual acuity gain and CMT reduction at 1 year, injection numbers at 2 years in neovascular AMD patients treated with anti-VEGF agents. However, the results of this meta-analysis should be interpreted with caution because of the heterogeneity among study designs. Eyes with VMA/VMT on optical coherence tomography at baseline may require more intensive treatment with decreased response to anti-VEGF agents.

Quantitative Choriocapillaris Perfusion Before and After Vitrectomy in Idiopathic Epiretinal Membrane by Optical Coherence Tomography Angiography.

To compare choriocapillaris perfusion of the fovea between patients with idiopathic epiretinal membrane (iERM) and normal controls and determine whether surgery affects it.

What Directions Do We Look at Power from? Up-Down, Left-Right, and Front-Back.

Three experiments were carried out to investigate whether the the kinship concept had spatial representations along up-down (Experiment 1), left-right (Experiment 2), and front-back (Experiment 3) orientation. Participants identified the letter P or Q after judging whether kinship words were elder or junior terms. The results showed that participants responded faster to letters placed at the top, right side, and front following elder terms, and faster at the bottom, left side, and back following junior terms. The regression results further confirmed that these shifts of attention along up-down, right-left, and front-back dimensions in external space were uniquely attributed to the power construct embedded in the kinship concept, but not number or time. The results provide evidence for the multiple spatial representations in power, and can be explained by the theoretical construct of structural mapping.

The effect of sign language structure on complex word reading in Chinese deaf adolescents.

The present study was carried out to investigate whether sign language structure plays a role in the processing of complex words (i.e., derivational and compound words), in particular, the delay of complex word reading in deaf adolescents. Chinese deaf adolescents were found to respond faster to derivational words than to compound words for one-sign-structure words, but showed comparable performance for two-sign-structure words. For both derivational and compound words, response latencies to one-sign-structure words were shorter than to two-sign-structure words. These results provide strong evidence that the structure of sign language affects written word processing in Chinese. Additionally, differences between derivational and compound words in the one-sign-structure condition indicate that Chinese deaf adolescents acquire print morphological awareness. The results also showed that delayed word reading was found in derivational words with two signs (DW-2), compound words with one sign (CW-1), and compound words with two signs (CW-2), but not in derivational words with one sign (DW-1), with the delay being maximum in DW-2, medium in CW-2, and minimum in CW-1, suggesting that the structure of sign language has an impact on the delayed processing of Chinese written words in deaf adolescents. These results provide insight into the mechanisms about how sign language structure affects written word processing and its delayed processing relative to their hearing peers of the same age.

Perceived physical appearance and life satisfaction: a moderated mediation model of self-esteem and life experience of deaf and hearing adolescents.

In this study, we investigated the relationship between perceived physical appearance and life satisfaction, and the role of self-esteem as mediator and life experience as moderator of the relationship in deaf and hearing adolescents. 118 Chinese deaf adolescents (55.1% male; mean age = 15.12 years, standard deviation [SD] = 2.13) from 5 special education schools and 132 Chinese hearing adolescents (53.8% male; mean age = 13.11 years, SD = .85) completed anonymous questionnaires regarding perceived physical appearance, self-esteem, and life satisfaction. Perceived physical appearance, self-esteem, and life satisfaction were significantly and positively associated with each other. Moreover, self-esteem partially mediated the relationship between perceived physical appearance and life satisfaction; however, this indirect link was weaker for deaf adolescents than it was for hearing adolescents. Implications of the findings and future research directions are discussed, as are potential interventions that can be applied to increase subjective well-being in deaf adolescents.

Efficacy and safety of intrauterine Bakri balloon tamponade in the treatment of postpartum hemorrhage: a multicenter analysis of 109 cases.

To evaluate the efficacy and safety of the Bakri balloon in the treatment of postpartum hemorrhage (PPH).

Maltreatment and Delinquency in China: Examining and Extending the Intervening Process of General Strain Theory.

Using a sample of 1,163 adolescents from four middle schools in China, this study explores the intervening process of how adolescent maltreatment is related to delinquency within the framework of general strain theory (GST) by comparing two models. The first model is Agnew's integrated model of GST, which examines the mediating effects of social control, delinquent peer affiliation, state anger, and depression on the relationship between maltreatment and delinquency. Based on this model, with the intent to further explore the mediating effects of state anger and depression and to investigate whether their effects on delinquency can be demonstrated more through delinquent peer affiliation and social control, an extended model (Model 2) is proposed by the authors. The second model relates state anger to delinquent peer affiliation and state depression to social control. By comparing the fit indices and the significance of the hypothesized paths of the two models, the study found that the extended model can better reflect the mechanism of how maltreatment contributes to delinquency, whereas the original integrated GST model only receives partial support because of its failure to find the mediating effects of state negative emotions.

Event-related potentials reveal linguistic suppression effect but not enhancement effect on categorical perception of color.

The present study used the event-related potential technique to investigate the nature of linguistic effect on color perception. Four types of stimuli based on hue differences between a target color and a preceding color were used: zero hue step within-category color (0-WC); one hue step within-category color (1-WC); one hue step between-category color (1-BC); and two hue step between-category color (2-BC). The ERP results showed no significant effect of stimulus type in the 100-200 ms time window. However, in the 200-350 ms time window, ERP responses to 1-WC target color overlapped with that to 0-WC target color for right visual field (RVF) but not left visual field (LVF) presentation. For the 1-BC condition, ERP amplitudes were comparable in the two visual fields, both being significantly different from the 0-WC condition. The 2-BC condition showed the same pattern as the 1-BC condition. These results suggest that the categorical perception of color in RVF is due to linguistic suppression on within-category color discrimination but not between-category color enhancement, and that the effect is independent of early perceptual processes.

Comparison of the effects between intravitreal and periocular injections of adenoviral vectored pigment epithelium-derived factor on suppressing choroidal neovascularization in rats.

To compare the effects between intravitreal and periocular injections of adenoviral vectored pigment epithelium-derived factor (AdPEDF) on suppressing established choroidal neovascularization (CNV) in rats.

Preoperative plasma fibrinogen, platelet count and prognosis in epithelial ovarian cancer.

The aim of the present study was to investigate the correlation between fibrinogen level, platelet count and prognosis in patients with epithelial ovarian cancer (EOC).

Gene deletions and amplifications in human hepatocellular carcinomas: correlation with hepatocyte growth regulation.

Tissues from 98 human hepatocellular carcinomas (HCCs) obtained from hepatic resections were subjected to somatic copy number variation (CNV) analysis. Most of these HCCs were discovered in livers resected for orthotopic transplantation, although in a few cases, the tumors themselves were the reason for the hepatectomies. Genomic analysis revealed deletions and amplifications in several genes, and clustering analysis based on CNV revealed five clusters. The LSP1 gene had the most cases with CNV (46 deletions and 5 amplifications). High frequencies of CNV were also seen in PTPRD (21/98), GNB1L (18/98), KIAA1217 (18/98), RP1-1777G6.2 (17/98), ETS1 (11/98), RSU1 (10/98), TBC1D22A (10/98), BAHCC1 (9/98), MAML2 (9/98), RAB1B (9/98), and YIF1A (9/98). The existing literature regarding hepatocytes or other cell types has connected many of these genes to regulation of cytoskeletal architecture, signaling cascades related to growth regulation, and transcription factors directly interacting with nuclear signaling complexes. Correlations with existing literature indicate that genomic lesions associated with HCC at the level of resolution of CNV occur on many genes associated directly or indirectly with signaling pathways operating in liver regeneration and hepatocyte growth regulation.

UV promoted phenanthridine syntheses from oxime carbonate derived iminyl radicals.

Oxime carbonates were found to be excellent precursors for the clean and direct generation of iminyl radicals under UV irradiation. Suitably functionalised iminyls underwent cyclisations yielding various phenanthridines and also substituted quinolines and isoquinolines. EPR and X-ray analyses of oxime carbonates provided insight into the mechanism.

Up-regulation of Wnt5A in chronic rhinosinusitis with nasal polyps.

Wnt5A contributes to the inflammatory activation of mononuclear cells and tissue remodeling. Hence we compared Wnt5A expression between chronic rhinosinusitis (CRS) patients with and without nasal polyps (NPs), analyzed its possible role in the pathogenesis of CRS.

Construction and identification of eukaryotic plasmid pGC-silencer-U6/Neo/GFP/ABCG2.

To construct three short hairpin RNA (shRNA) interference expression plasmid vectors of human ABCG2 gene, to assay the expression of ABCG2 in a human nasopharyngeal carcinoma (NPC) cell line, CEN-2 cell line, and to detect the RNAi effect of shRNA.

Dysregulation of E-cadherin in chronic rhinosinusitis with nasal polyps.

E-cadherin is a key epithelial protein and adhesive molecule. This study detected the E-cadherin expression in patients with chronic rhinosinusitis with nasal polyps (CRSwNP) and controls, and analyzed its possible role in the pathogenesis of CRSwNP. The expression of E-cadherin was detected by using Western blotting and immunohistochemistry in controls and patients with CRSwNP. Computed tomography (CT) scan findings were scored. The results showed that the E-cadherin expression was up-regulated in patients with CRSwNP as compared with controls (P=0.039) and the positive staining was predominantly localized on the epithelial cell membrane. E-cadherin level was correlated negatively with Lund-Mackay scores in patients with CRSwNP (r=-0.604, P=0.005). It is suggested that E-cadherin may be involved in the pathogenesis of CRSwNP and correlated with disease severity.

Rapid determination of cyanide in human plasma and urine by gas chromatography-mass spectrometry with two-step derivatization.

Cyanide (CN) is a powerful poison and rapidly toxic agent. Because of its wide availability and high toxicity, quantification of CN in blood and urine is frequently required in clinical and forensic practice. We present a sensitive and less time consuming method based on solid-supported liquid-liquid extraction (SLE) and gas chromatography-mass spectrometry (GC-MS) with two-step derivatization for determination of CN in plasma and urine. Buffer solution, 1,3,5-tribromobenzene (internal standard) and benzaidehyde were added to sample to complete the first-step derivatization. Then the analytes were poured onto the column of diatomaceous earth, eluted with n-hexane containing 0.4% of heptafluorobutyryl chloride (HFB-Cl) to complete the second-step derivatization forming the final analyte, heptafluoro-butyric acid-alpha-cyanobenzyl ester. This method was linear (r(2)=0.9988, 0.9993), reproducible (intra-day RSD=4.37-7.24%, 3.19-5.74%; inter-day RSD=5.13-7.63%, 4.31-6.69%), accurate (recoveries=90.58-115.56%, 93.01-114.6%) and sensitive (LOD=0.04, 0.01microg/mL) for plasma and urine, respectively. The total time was about 25min. This method was successfully applied to the analysis of blood sample and urine sample collected from a victim who died as a result of ingestion of potassium cyanide.

Fibrous dysplasia involving sphenoid and occipital bone: one case report and literature review.

To study the clinical manifestation, radiograph features, pathology, diagnosis and treatment of fibrous dysplasia in cranial bone.

Rapid and simultaneous determination of hair polyamines as N-heptafluorobutyryl derivatives by gas chromatography-mass spectrometry.

We have developed a simple and sensitive method for the simultaneous determination of putrescine, spermidine and spermine in hair as their N-heptafluorobutyryl derivatives by gas chromatography-mass spectrometry (GC-MS) in selected ion-monitoring (SIM) mode. After base hydrolysis, hair samples were extracted with solid-phase extraction (SPE) with diatomaceous earth columns, followed by derivatization with heptafluorobutyryl chloride (HFB-Cl) and elution with n-hexane simultaneously. This method was linear (r> or =0.9989), reproducible (intra-day R.S.D.=3.4-15.5%, inter-day R.S.D.=2.6-14.6%), accurate (recoveries=67.8-94.6%) and sensitive (LOD=0.05-1.0 ng). The method was successfully applied to the analysis of 36 hair samples from 14 healthy men and 22 healthy women. Results showed that the levels of hair polyamines were 4.39-12.15 microg/g for putrescine, 3.89-27.91 microg/g for spermidine, and 0.81-15.15 microg/g for spermine. Either in the male or female group, the most abundant hair polyamine was spermidine, followed by putrescine and spermine, while the mean levels of the three polyamines in hair samples were all found to be higher in men than in women.