PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

Structure and regulated expression of mammalian RUNX genes.

Abstract The RUNX are key regulators of lineage-specific gene expression in major developmental pathways. The expression of RUNX genes is tightly regulated, leading to a highly specific spatio/temporal expression pattern and to distinct phenotypes of gene knockouts. This review highlights the extensive structural similarities between the three mammalian RUNX genes and delineates how regulation of their expression at the levels of transcription and translation are orchestrated into the unique RUNX expression pattern.
PMID
Related Publications

Homologs of RUNX and CBF beta/PEBP2 beta in C. elegans.

Coordinate regulation of cell growth and differentiation by TGF-beta superfamily and Runx proteins.

Epigenetic gene silencing by Runx proteins.

The Runx genes: lineage-specific oncogenes and tumor suppressors.

Role of RUNX family members in transcriptional repression and gene silencing.

Authors

Mayor MeshTerms
Keywords
Journal Title oncogene
Publication Year Start




PMID- 15156175
OWN - NLM
STAT- MEDLINE
DA  - 20040524
DCOM- 20040615
LR  - 20061115
IS  - 0950-9232 (Print)
IS  - 0950-9232 (Linking)
VI  - 23
IP  - 24
DP  - 2004 May 24
TI  - Structure and regulated expression of mammalian RUNX genes.
PG  - 4211-9
AB  - The RUNX are key regulators of lineage-specific gene expression in major
      developmental pathways. The expression of RUNX genes is tightly regulated,
      leading to a highly specific spatio/temporal expression pattern and to distinct
      phenotypes of gene knockouts. This review highlights the extensive structural
      similarities between the three mammalian RUNX genes and delineates how regulation
      of their expression at the levels of transcription and translation are
      orchestrated into the unique RUNX expression pattern.
FAU - Levanon, Ditsa
AU  - Levanon D
AD  - Department of Molecular Genetics, The Weizmann Institute of Science, Rehovot
      76100, Israel.
FAU - Groner, Yoram
AU  - Groner Y
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - England
TA  - Oncogene
JT  - Oncogene
JID - 8711562
RN  - 0 (Core Binding Factor Alpha 2 Subunit)
RN  - 0 (Core Binding Factor Alpha 3 Subunit)
RN  - 0 (Core Binding Factor alpha Subunits)
RN  - 0 (DNA-Binding Proteins)
RN  - 0 (Neoplasm Proteins)
RN  - 0 (Proto-Oncogene Proteins)
RN  - 0 (RUNX1 protein, human)
RN  - 0 (Runx1 protein, mouse)
RN  - 0 (Runx3 protein, human)
RN  - 0 (Runx3 protein, mouse)
RN  - 0 (Transcription Factors)
SB  - IM
MH  - Animals
MH  - Core Binding Factor Alpha 2 Subunit
MH  - Core Binding Factor Alpha 3 Subunit
MH  - Core Binding Factor alpha Subunits
MH  - DNA-Binding Proteins/*genetics/metabolism
MH  - Gene Expression Regulation/*physiology
MH  - Humans
MH  - Mice
MH  - Neoplasm Proteins/*genetics/metabolism
MH  - Proto-Oncogene Proteins/*genetics/metabolism
MH  - Sequence Analysis, DNA
MH  - Transcription Factors/*genetics/metabolism
MH  - Transcription, Genetic/physiology
RF  - 123
EDAT- 2004/05/25 05:00
MHDA- 2004/06/16 05:00
CRDT- 2004/05/25 05:00
AID - 10.1038/sj.onc.1207670 [doi]
AID - 1207670 [pii]
PST - ppublish
SO  - Oncogene. 2004 May 24;23(24):4211-9.