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PMID- 17584999
DCOM- 20080118
LR  - 20080528
IS  - 1468-2079 (Electronic)
IS  - 0007-1161 (Linking)
VI  - 92
IP  - 1
DP  - 2008 Jan
TI  - Vision-related quality of life in patients with diabetic macular oedema.
PG  - 89-92
AB  - AIMS: The aim of this study was to determine the impact of diabetic macular
      oedema (DME) on the quality of life (QOL) in patients with type 2 diabetes
      mellitus. METHODS: The study was a prospective, consecutive, non-comparative case
      series. An observational study evaluated the quality of vision and
      vision-specific QOL using the 25-item National Eye Institute Visual Function
      Questionnaire (NEI VFQ-25). Mean VFQ-25 subscale scores in type 2 diabetic study 
      patients were compared with mean VFQ-25 subscale score in groups of patients with
      type 1 diabetic retinopathy (T1DR) and varying degrees of age-related macular
      degeneration (ARMD), glaucoma and cataracts and in reference populations.
      RESULTS: Thirty-three patients completed the NEI VFQ-25. The mean age of the
      study population was 64 years. When performing a comparison of those patients
      with DME versus those with isolated T1DR we found that for the general health
      subscale, the DME versus T1DR group means were 42+/-4.4 versus 61+/-1.0
      respectively. The DME versus T1DR quality of vision categorical mean scores were 
      69+/-4.1 versus 93+/-3.9. The DME versus T1DR VR-QOL categorical mean scores were
      62+/-5.0 versus 93+/-1.0. The DME group was significantly worse in each of these 
      three categories compared with the T1DR group (p<0.01). An additional analysis
      was performed to examine the differences in VR-QOL in the DME group versus
      varying common ocular diseases, including age-related macular degeneration
      (ARMD), glaucoma, cataracts and disease-free reference groups. The mean values of
      VFQ-25 subscale in the DME group were significantly lower then the glaucoma group
      in ten of 12 subscales, the cataract group in 11 of 12 subscales, and the
      reference group in 12 of 12 subscales. However, the mean values of VFQ-25
      subscale in the DME group were only significantly different from the ARMD group
      in three of 12 subscales. CONCLUSIONS: Type 2 diabetes patients with macular
      oedema experience a decreased VR-QOL compared with type 1 diabetic patients with 
      diabetic retinopathy, glaucoma or cataracts. However, VR-QOL in type 2 diabetic
      patients with macular oedema was similar to those individuals with ARMD.
FAU - Hariprasad, S M
AU  - Hariprasad SM
AD  - Department of Ophthalmology and Visual Science, University of Chicago, 5841 South
      Maryland, MC 2114, Chicago, IL 60637, USA. [email protected]
FAU - Mieler, W F
AU  - Mieler WF
FAU - Grassi, M
AU  - Grassi M
FAU - Green, J L
AU  - Green JL
FAU - Jager, R D
AU  - Jager RD
FAU - Miller, L
AU  - Miller L
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20070621
PL  - England
TA  - Br J Ophthalmol
JT  - The British journal of ophthalmology
JID - 0421041
SB  - IM
MH  - Aged
MH  - Cataract/complications/psychology/rehabilitation
MH  - Diabetes Mellitus, Type 1/complications/psychology
MH  - Diabetes Mellitus, Type 2/*complications/psychology
MH  - Diabetic Retinopathy/etiology/psychology/*rehabilitation
MH  - Female
MH  - Glaucoma/complications/psychology/rehabilitation
MH  - Health Status Indicators
MH  - Humans
MH  - Macular Degeneration/complications/psychology/rehabilitation
MH  - Macular Edema/etiology/psychology/*rehabilitation
MH  - Male
MH  - Middle Aged
MH  - Prospective Studies
MH  - Psychometrics
MH  - *Quality of Life
MH  - Vision Disorders/etiology/psychology/*rehabilitation
EDAT- 2007/06/23 09:00
MHDA- 2008/01/19 09:00
CRDT- 2007/06/23 09:00
PHST- 2007/06/23 09:00 [pubmed]
PHST- 2008/01/19 09:00 [medline]
PHST- 2007/06/23 09:00 [entrez]
AID - bjo.2007.122416 [pii]
AID - 10.1136/bjo.2007.122416 [doi]
PST - ppublish
SO  - Br J Ophthalmol. 2008 Jan;92(1):89-92. doi: 10.1136/bjo.2007.122416. Epub 2007
      Jun 21.