PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

Medium-chain triglyceride ketogenic diet, an effective treatment for drug-resistant epilepsy and a comparison with other ketogenic diets.

Abstract The ketogenic diet (KD) is one of the most effective therapies for drug-resistant epilepsy. The efficacy of the medium-chain triglyceride KD (MCTKD) is as excellent as the classic KD (CKD), which has been documented in several subsequent retrospective, prospective, and randomized studies. MCT oil is more ketogenic than long-chain triglycerides. Therefore, the MCTKD allows more carbohydrate and protein food, which makes the diet more palatable than the CKD. The MCTKD is not based on diet ratios as is the CKD, but uses a percentage of calories from MCT oil to create ketones. There has also been literature which documents the associated gastrointestinal side effects from the MCTKD, such as diarrhea, vomiting, bloating, and cramps. Therefore, the MCTKD has been an underutilized diet therapy for intractable epilepsy among children.The author has used up to >70% MCTKD diet to maximize seizure control with gastrointestinal side effects optimally controlled. As long as health care professionals carefully manage MCTKD, many more patients with epilepsy who are not appropriate for CKD or modified Atkins diet or low glycemic index treatment will benefit from this treatment. A comparison between the MCTKD and other KDs is also discussed.
PMID
Related Publications

Prospective study of the modified atkins diet in combination with a ketogenic liquid supplement during the initial month.

Efficacy of dietary treatments for epilepsy.

Ketogenic diet for epilepsy treatment.

Medium-chain triglyceride (MCT) ketogenic therapy.

Alternative diets to the classical ketogenic diet--can we be more liberal?

Authors

Mayor MeshTerms

Diet, Ketogenic

Keywords
Journal Title biomedical journal
Publication Year Start




PMID- 23515148
OWN - NLM
STAT- MEDLINE
DCOM- 20131210
LR  - 20171116
IS  - 2320-2890 (Electronic)
IS  - 2319-4170 (Linking)
VI  - 36
IP  - 1
DP  - 2013 Jan-Feb
TI  - Medium-chain triglyceride ketogenic diet, an effective treatment for
      drug-resistant epilepsy and a comparison with other ketogenic diets.
PG  - 9-15
LID - 10.4103/2319-4170.107154 [doi]
AB  - The ketogenic diet (KD) is one of the most effective therapies for drug-resistant
      epilepsy. The efficacy of the medium-chain triglyceride KD (MCTKD) is as
      excellent as the classic KD (CKD), which has been documented in several
      subsequent retrospective, prospective, and randomized studies. MCT oil is more
      ketogenic than long-chain triglycerides. Therefore, the MCTKD allows more
      carbohydrate and protein food, which makes the diet more palatable than the CKD. 
      The MCTKD is not based on diet ratios as is the CKD, but uses a percentage of
      calories from MCT oil to create ketones. There has also been literature which
      documents the associated gastrointestinal side effects from the MCTKD, such as
      diarrhea, vomiting, bloating, and cramps. Therefore, the MCTKD has been an
      underutilized diet therapy for intractable epilepsy among children.The author has
      used up to >70% MCTKD diet to maximize seizure control with gastrointestinal side
      effects optimally controlled. As long as health care professionals carefully
      manage MCTKD, many more patients with epilepsy who are not appropriate for CKD or
      modified Atkins diet or low glycemic index treatment will benefit from this
      treatment. A comparison between the MCTKD and other KDs is also discussed.
FAU - Liu, Yeou-mei Christiana
AU  - Liu YM
AD  - Division of Neurology, Hospital for Sick Children, Toronto, Ontario, Canada.
      [email protected]
FAU - Wang, Huei-Shyong
AU  - Wang HS
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Biomed J
JT  - Biomedical journal
JID - 101599820
RN  - 0 (Triglycerides)
SB  - IM
MH  - Diet, Carbohydrate-Restricted
MH  - *Diet, Ketogenic
MH  - Dietary Supplements
MH  - Epilepsy/*diet therapy
MH  - Glycemic Index/physiology
MH  - Humans
MH  - Treatment Outcome
MH  - Triglycerides/*metabolism
EDAT- 2013/03/22 06:00
MHDA- 2013/12/16 06:00
CRDT- 2013/03/22 06:00
PHST- 2013/03/22 06:00 [entrez]
PHST- 2013/03/22 06:00 [pubmed]
PHST- 2013/12/16 06:00 [medline]
AID - BiomedJ_2013_36_1_9_107154 [pii]
AID - 10.4103/2319-4170.107154 [doi]
PST - ppublish
SO  - Biomed J. 2013 Jan-Feb;36(1):9-15. doi: 10.4103/2319-4170.107154.