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%A Snow, Thomas M.; Ludman, Peter; Banya, Winston; DeBelder, Mark; MacCarthy, Philip M.; Davies, Simon W.; Di Mario, Carlo; Moat, Neil E.
%T Management of concomitant coronary artery disease in patients undergoing transcatheter aortic valve implantation: the United Kingdom TAVI Registry.
%J International journal of cardiology, vol. 199, pp. 253-260
%D 11/2015
%V 199
%M eng
%B The management and impact of concomitant coronary artery disease in patients referred for TAVI remains contentious. We describe the prevalence, clinical impact and management of coronary artery disease (CAD) in patients in the United Kingdom TAVI Registry.
%K Aged, Aged, 80 and over, Aortic Valve Stenosis, Coronary Angiography, Coronary Artery Disease, Disease Management, Echocardiography, Female, Great Britain, Humans, Male, Percutaneous Coronary Intervention, Retrospective Studies, Transcatheter Aortic Valve Replacement, Treatment Outcome
%P 253
%L 260
%Y 10.1016/j.ijcard.2015.06.166
%W PHY
%G AUTHOR
%R 2015......199..253S

@Article{Snow2015,
author="Snow, Thomas M.
and Ludman, Peter
and Banya, Winston
and DeBelder, Mark
and MacCarthy, Philip M.
and Davies, Simon W.
and Di Mario, Carlo
and Moat, Neil E.",
title="Management of concomitant coronary artery disease in patients undergoing transcatheter aortic valve implantation: the United Kingdom TAVI Registry.",
journal="International journal of cardiology",
year="2015",
month="Nov",
day="15",
volume="199",
pages="253--260",
keywords="Aged",
keywords="Aged, 80 and over",
keywords="Aortic Valve Stenosis",
keywords="Coronary Angiography",
keywords="Coronary Artery Disease",
keywords="Disease Management",
keywords="Echocardiography",
keywords="Female",
keywords="Great Britain",
keywords="Humans",
keywords="Male",
keywords="Percutaneous Coronary Intervention",
keywords="Retrospective Studies",
keywords="Transcatheter Aortic Valve Replacement",
keywords="Treatment Outcome",
abstract="The management and impact of concomitant coronary artery disease in patients referred for TAVI remains contentious. We describe the prevalence, clinical impact and management of coronary artery disease (CAD) in patients in the United Kingdom TAVI Registry.",
issn="1874-1754",
doi="10.1016/j.ijcard.2015.06.166",
url="http://www.ncbi.nlm.nih.gov/pubmed/26209948",
language="eng"
}

%0 Journal Article
%T Management of concomitant coronary artery disease in patients undergoing transcatheter aortic valve implantation: the United Kingdom TAVI Registry.
%A Snow, Thomas M.
%A Ludman, Peter
%A Banya, Winston
%A DeBelder, Mark
%A MacCarthy, Philip M.
%A Davies, Simon W.
%A Di Mario, Carlo
%A Moat, Neil E.
%J International journal of cardiology
%D 2015
%8 Nov 15
%V 199
%@ 1874-1754
%G eng
%F Snow2015
%X The management and impact of concomitant coronary artery disease in patients referred for TAVI remains contentious. We describe the prevalence, clinical impact and management of coronary artery disease (CAD) in patients in the United Kingdom TAVI Registry.
%K Aged
%K Aged, 80 and over
%K Aortic Valve Stenosis
%K Coronary Angiography
%K Coronary Artery Disease
%K Disease Management
%K Echocardiography
%K Female
%K Great Britain
%K Humans
%K Male
%K Percutaneous Coronary Intervention
%K Retrospective Studies
%K Transcatheter Aortic Valve Replacement
%K Treatment Outcome
%U http://dx.doi.org/10.1016/j.ijcard.2015.06.166
%U http://www.ncbi.nlm.nih.gov/pubmed/26209948
%P 253-260

PT Journal
AU Snow, TM
   Ludman, P
   Banya, W
   DeBelder, M
   MacCarthy, PM
   Davies, SW
   Di Mario, C
   Moat, NE
TI Management of concomitant coronary artery disease in patients undergoing transcatheter aortic valve implantation: the United Kingdom TAVI Registry.
SO International journal of cardiology
JI Int. J. Cardiol.
PD Nov
PY 2015
BP 253
EP 260
VL 199
DI 10.1016/j.ijcard.2015.06.166
LA eng
DE Aged; Aged, 80 and over; Aortic Valve Stenosis; Coronary Angiography; Coronary Artery Disease; Disease Management; Echocardiography; Female; Great Britain; Humans; Male; Percutaneous Coronary Intervention; Retrospective Studies; Transcatheter Aortic Valve Replacement; Treatment Outcome
AB The management and impact of concomitant coronary artery disease in patients referred for TAVI remains contentious. We describe the prevalence, clinical impact and management of coronary artery disease (CAD) in patients in the United Kingdom TAVI Registry.
ER

PMID- 26209948
OWN - NLM
STAT- MEDLINE
DA  - 20150915
DCOM- 20160621
IS  - 1874-1754 (Electronic)
IS  - 0167-5273 (Linking)
VI  - 199
DP  - 2015 Nov 15
TI  - Management of concomitant coronary artery disease in patients undergoing
      transcatheter aortic valve implantation: the United Kingdom TAVI Registry.
PG  - 253-60
LID - 10.1016/j.ijcard.2015.06.166 [doi]
LID - S0167-5273(15)30093-0 [pii]
AB  - BACKGROUND: The management and impact of concomitant coronary artery disease in
      patients referred for TAVI remains contentious. We describe the prevalence,
      clinical impact and management of coronary artery disease (CAD) in patients in
      the United Kingdom TAVI Registry. METHODS: All-inclusive study of patients
      undergoing TAVI in the United Kingdom (excluding Northern Ireland) from January
      2007 to December 2011. Coronary artery disease at the time of TAVI was
      demonstrated on invasive angiography. RESULTS: 2588 consecutive patients were
      entered in the U.K. TAVI Registry. CAD was reported in 1171 pts with left main
      stem involvement in 12.4% of this cohort (n=145). Most patients were free of
      chest pain, but limited by dyspnoea (NYHA Class III & IV 81.9%). Angina was
      however more prevalent in those patients with CAD (p<0.0001). Hybrid PCI was
      uncommon, performed in only 14.7% of the CAD cohort (n=172). Survival at 30days, 
      1year, and 4years was 93.7%, 81.4% and 72.0% respectively. Adjusting for
      confounders in a multivariate model the presence and extent of CAD was not
      associated with early (30-days, p=0.36) or late (4years, p=0.10) survival.
      CONCLUSIONS: This contemporary study of coronary artery disease management in an 
      "all-comers" patient population undergoing TAVI demonstrates that whilst often an
      indicator of significant underlying comorbidity coronary artery disease is not
      associated with decreased short or long-term survival. The majority of patients
      with aortic stenosis and concomitant CAD can be managed effectively by TAVI
      alone. However, the importance of the Heart Team in making decisions on
      individual patients must not be underestimated.
CI  - Copyright (c) 2015 Elsevier Ireland Ltd. All rights reserved.
FAU - Snow, Thomas M
AU  - Snow TM
AD  - Cardiovascular Biomedical Research Unit Royal Brompton & Harefield NHS Foundation
      Trust, London, UK.
FAU - Ludman, Peter
AU  - Ludman P
AD  - Queen Elizabeth Hospital, Birmingham, UK.
FAU - Banya, Winston
AU  - Banya W
AD  - Cardiovascular Biomedical Research Unit Royal Brompton & Harefield NHS Foundation
      Trust, London, UK; Imperial College, London, UK.
FAU - DeBelder, Mark
AU  - DeBelder M
AD  - The James Cook University Hospital, Middlesbrough, UK.
FAU - MacCarthy, Philip M
AU  - MacCarthy PM
AD  - King's College Hospital, London, UK.
FAU - Davies, Simon W
AU  - Davies SW
AD  - Cardiovascular Biomedical Research Unit Royal Brompton & Harefield NHS Foundation
      Trust, London, UK.
FAU - Di Mario, Carlo
AU  - Di Mario C
AD  - Cardiovascular Biomedical Research Unit Royal Brompton & Harefield NHS Foundation
      Trust, London, UK; Imperial College, London, UK.
FAU - Moat, Neil E
AU  - Moat NE
AD  - Cardiovascular Biomedical Research Unit Royal Brompton & Harefield NHS Foundation
      Trust, London, UK. Electronic address: [email protected]
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20150704
PL  - Netherlands
TA  - Int J Cardiol
JT  - International journal of cardiology
JID - 8200291
SB  - IM
MH  - Aged
MH  - Aged, 80 and over
MH  - Aortic Valve Stenosis/complications/diagnosis/*surgery
MH  - Coronary Angiography
MH  - Coronary Artery Disease/complications/diagnosis/*surgery
MH  - *Disease Management
MH  - Echocardiography
MH  - Female
MH  - Great Britain
MH  - Humans
MH  - Male
MH  - Percutaneous Coronary Intervention/*methods
MH  - Retrospective Studies
MH  - Transcatheter Aortic Valve Replacement/*methods
MH  - Treatment Outcome
OTO - NOTNLM
OT  - Aortic valve disease
OT  - Coronary artery disease
OT  - Transcatheter aortic valve implantation
EDAT- 2015/07/27 06:00
MHDA- 2016/06/22 06:00
CRDT- 2015/07/27 06:00
PHST- 2015/04/19 [received]
PHST- 2015/06/23 [revised]
PHST- 2015/06/27 [accepted]
PHST- 2015/07/04 [aheadofprint]
AID - S0167-5273(15)30093-0 [pii]
AID - 10.1016/j.ijcard.2015.06.166 [doi]
PST - ppublish
SO  - Int J Cardiol. 2015 Nov 15;199:253-60. doi: 10.1016/j.ijcard.2015.06.166. Epub
      2015 Jul 4.
TY  - JOUR
AU  - Snow, Thomas M.
AU  - Ludman, Peter
AU  - Banya, Winston
AU  - DeBelder, Mark
AU  - MacCarthy, Philip M.
AU  - Davies, Simon W.
AU  - Di Mario, Carlo
AU  - Moat, Neil E.
PY  - 2015/Nov/15
TI  - Management of concomitant coronary artery disease in patients undergoing transcatheter aortic valve implantation: the United Kingdom TAVI Registry.
T2  - Int. J. Cardiol.
JO  - International journal of cardiology
SP  - 253
EP  - 260
VL  - 199
KW  - Aged
KW  - Aged, 80 and over
KW  - Aortic Valve Stenosis
KW  - Coronary Angiography
KW  - Coronary Artery Disease
KW  - Disease Management
KW  - Echocardiography
KW  - Female
KW  - Great Britain
KW  - Humans
KW  - Male
KW  - Percutaneous Coronary Intervention
KW  - Retrospective Studies
KW  - Transcatheter Aortic Valve Replacement
KW  - Treatment Outcome
N2  - The management and impact of concomitant coronary artery disease in patients referred for TAVI remains contentious. We describe the prevalence, clinical impact and management of coronary artery disease (CAD) in patients in the United Kingdom TAVI Registry.
SN  - 1874-1754
UR  - http://dx.doi.org/10.1016/j.ijcard.2015.06.166
UR  - http://www.ncbi.nlm.nih.gov/pubmed/26209948
ID  - Snow2015
ER  - 
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