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PMID- 26488632
DA  - 20160109
DCOM- 20160826
LR  - 20160109
IS  - 1536-4798 (Electronic)
IS  - 0277-3740 (Linking)
VI  - 35
IP  - 2
DP  - 2016 Feb
TI  - Systemic Comorbidities of Dry Eye Syndrome: The Korean National Health and
      Nutrition Examination Survey V, 2010 to 2012.
PG  - 187-92
LID - 10.1097/ICO.0000000000000657 [doi]
AB  - PURPOSE: To identify systemic comorbidities in patients with dry eye syndrome in 
      South Korea. METHODS: From 2010 to 2012, 17,364 participants aged 20 or older
      were randomly included in the nationwide Korean National Health and Nutrition
      Examination Survey V. The prevalence of dry eye syndrome and demographics of
      these patients were investigated. We performed conditional logistic regression
      analyses based on age, sex, residential area, education level, occupation type,
      and household income level to obtain the odds ratio for each systemic comorbidity
      among subjects with and without dry eye syndrome. RESULTS: The prevalence of dry 
      eye syndrome in this study was 10.4%. Age [adjusted odds ratio (AOR): 1.02],
      female gender (AOR: 3.01), and indoor occupation (AOR: 1.30) were associated with
      a higher prevalence of dry eye syndrome and found to be less prevalent in those
      residing in rural areas (AOR: 0.73) and with lower education levels (AOR:
      0.66-0.99). With regard to systemic comorbidities, dyslipidemia (AOR: 1.63),
      degenerative arthritis (AOR: 1.56), rheumatoid arthritis (AOR: 1.44), thyroid
      disease (AOR: 1.79), and renal failure (AOR: 2.56) were associated with a
      significantly higher prevalence of dry eye syndrome. CONCLUSIONS: We found that
      patients with dry eye syndrome have a higher prevalence of several systemic
      comorbidities. A more comprehensive therapeutic approach considering the effect
      of systemic medication may be necessary in these patients.
FAU - Roh, Hyun Cheol
AU  - Roh HC
AD  - *Department of Ophthalmology, Dongguk University, Ilsan Hospital, Goyang,
      Kyunggido, South Korea; and daggerDepartment of Ophthalmology and Visual
      Sciences, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, 
FAU - Lee, Jimmy K
AU  - Lee JK
FAU - Kim, Martha
AU  - Kim M
FAU - Oh, Jong-Hyun
AU  - Oh JH
FAU - Chang, Min-Wook
AU  - Chang MW
FAU - Chuck, Roy S
AU  - Chuck RS
FAU - Park, Choul Yong
AU  - Park CY
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Cornea
JT  - Cornea
JID - 8216186
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Arthritis, Rheumatoid/epidemiology
MH  - Comorbidity
MH  - Dry Eye Syndromes/*epidemiology
MH  - Dyslipidemias/epidemiology
MH  - Educational Status
MH  - Female
MH  - Health Surveys
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Nutrition Surveys
MH  - Osteoarthritis/epidemiology
MH  - Prevalence
MH  - Renal Insufficiency/epidemiology
MH  - Republic of Korea/epidemiology
MH  - Risk Factors
MH  - Rural Population/statistics & numerical data
MH  - Thyroid Diseases/epidemiology
MH  - Young Adult
EDAT- 2015/10/22 06:00
MHDA- 2016/08/27 06:00
CRDT- 2015/10/22 06:00
AID - 10.1097/ICO.0000000000000657 [doi]
PST - ppublish
SO  - Cornea. 2016 Feb;35(2):187-92. doi: 10.1097/ICO.0000000000000657.

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