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Zika virus infection in a traveller returning from the Maldives, June 2015.

Abstract We report a Zika virus (ZIKV) infection in a patient with fever and rash after returning to Finland from Maldives, June 2015. The patient had dengue virus (DENV) IgG and IgM antibodies but pan-flavivirus RT-PCR and subsequent sequencing showed presence of ZIKV RNA in urine. Recent association of ZIKV with microcephaly highlights the need for laboratory differentiation of ZIKV from DENV infection and the circulation of ZIKV in areas outside its currently known distribution range.
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Authors

Mayor MeshTerms
Keywords

Zika virus

emerging infectious diseases

flavivirus

mosquito-borne

traveller

Journal Title euro surveillance : bulletin europe?en sur les maladies transmissibles = european communicable disease bulletin
Publication Year Start
%A Korhonen, Essi Marjana; Huhtamo, Eili; Smura, Teemu; Kallio-Kokko, Hannimari; Raassina, Markku; Vapalahti, Olli
%T Zika virus infection in a traveller returning from the Maldives, June 2015.
%J Euro surveillance : bulletin Europe?en sur les maladies transmissibles = European communicable disease bulletin, vol. 21, no. 2
%D 00/2016
%V 21
%N 2
%M eng
%B We report a Zika virus (ZIKV) infection in a patient with fever and rash after returning to Finland from Maldives, June 2015. The patient had dengue virus (DENV) IgG and IgM antibodies but pan-flavivirus RT-PCR and subsequent sequencing showed presence of ZIKV RNA in urine. Recent association of ZIKV with microcephaly highlights the need for laboratory differentiation of ZIKV from DENV infection and the circulation of ZIKV in areas outside its currently known distribution range.
%K Adult, Dengue, Dengue Virus, Exanthema, Fever, Finland, Humans, Indian Ocean Islands, Male, Molecular Sequence Data, RNA, Viral, Reverse Transcriptase Polymerase Chain Reaction, Sequence Analysis, RNA, Travel, Zika Virus, Zika Virus Infection
%Y 10.2807/1560-7917.ES.2016.21.2.30107
%W PHY
%G AUTHOR
%R 2016.......21.....K

@Article{Korhonen2016,
author="Korhonen, Essi Marjana
and Huhtamo, Eili
and Smura, Teemu
and Kallio-Kokko, Hannimari
and Raassina, Markku
and Vapalahti, Olli",
title="Zika virus infection in a traveller returning from the Maldives, June 2015.",
journal="Euro surveillance : bulletin Europe?en sur les maladies transmissibles = European communicable disease bulletin",
year="2016",
volume="21",
number="2",
keywords="Adult",
keywords="Dengue",
keywords="Dengue Virus",
keywords="Exanthema",
keywords="Fever",
keywords="Finland",
keywords="Humans",
keywords="Indian Ocean Islands",
keywords="Male",
keywords="Molecular Sequence Data",
keywords="RNA, Viral",
keywords="Reverse Transcriptase Polymerase Chain Reaction",
keywords="Sequence Analysis, RNA",
keywords="Travel",
keywords="Zika Virus",
keywords="Zika Virus Infection",
abstract="We report a Zika virus (ZIKV) infection in a patient with fever and rash after returning to Finland from Maldives, June 2015. The patient had dengue virus (DENV) IgG and IgM antibodies but pan-flavivirus RT-PCR and subsequent sequencing showed presence of ZIKV RNA in urine. Recent association of ZIKV with microcephaly highlights the need for laboratory differentiation of ZIKV from DENV infection and the circulation of ZIKV in areas outside its currently known distribution range.",
issn="1560-7917",
doi="10.2807/1560-7917.ES.2016.21.2.30107",
url="http://www.ncbi.nlm.nih.gov/pubmed/26794427",
language="eng"
}

%0 Journal Article
%T Zika virus infection in a traveller returning from the Maldives, June 2015.
%A Korhonen, Essi Marjana
%A Huhtamo, Eili
%A Smura, Teemu
%A Kallio-Kokko, Hannimari
%A Raassina, Markku
%A Vapalahti, Olli
%J Euro surveillance : bulletin Europe?en sur les maladies transmissibles = European communicable disease bulletin
%D 2016
%V 21
%N 2
%@ 1560-7917
%G eng
%F Korhonen2016
%X We report a Zika virus (ZIKV) infection in a patient with fever and rash after returning to Finland from Maldives, June 2015. The patient had dengue virus (DENV) IgG and IgM antibodies but pan-flavivirus RT-PCR and subsequent sequencing showed presence of ZIKV RNA in urine. Recent association of ZIKV with microcephaly highlights the need for laboratory differentiation of ZIKV from DENV infection and the circulation of ZIKV in areas outside its currently known distribution range.
%K Adult
%K Dengue
%K Dengue Virus
%K Exanthema
%K Fever
%K Finland
%K Humans
%K Indian Ocean Islands
%K Male
%K Molecular Sequence Data
%K RNA, Viral
%K Reverse Transcriptase Polymerase Chain Reaction
%K Sequence Analysis, RNA
%K Travel
%K Zika Virus
%K Zika Virus Infection
%U http://dx.doi.org/10.2807/1560-7917.ES.2016.21.2.30107
%U http://www.ncbi.nlm.nih.gov/pubmed/26794427

PT Journal
AU Korhonen, EM
   Huhtamo, E
   Smura, T
   Kallio-Kokko, H
   Raassina, M
   Vapalahti, O
TI Zika virus infection in a traveller returning from the Maldives, June 2015.
SO Euro surveillance : bulletin Europe?en sur les maladies transmissibles = European communicable disease bulletin
JI Euro Surveill.
PY 2016
VL 21
IS 2
DI 10.2807/1560-7917.ES.2016.21.2.30107
LA eng
DE Adult; Dengue; Dengue Virus; Exanthema; Fever; Finland; Humans; Indian Ocean Islands; Male; Molecular Sequence Data; RNA, Viral; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, RNA; Travel; Zika Virus; Zika Virus Infection
AB We report a Zika virus (ZIKV) infection in a patient with fever and rash after returning to Finland from Maldives, June 2015. The patient had dengue virus (DENV) IgG and IgM antibodies but pan-flavivirus RT-PCR and subsequent sequencing showed presence of ZIKV RNA in urine. Recent association of ZIKV with microcephaly highlights the need for laboratory differentiation of ZIKV from DENV infection and the circulation of ZIKV in areas outside its currently known distribution range.
ER

PMID- 26794427
OWN - NLM
STAT- MEDLINE
DA  - 20160122
DCOM- 20160526
IS  - 1560-7917 (Electronic)
IS  - 1025-496X (Linking)
VI  - 21
IP  - 2
DP  - 2016
TI  - Zika virus infection in a traveller returning from the Maldives, June 2015.
LID - 10.2807/1560-7917.ES.2016.21.2.30107 [doi]
AB  - We report a Zika virus (ZIKV) infection in a patient with fever and rash after
      returning to Finland from Maldives, June 2015. The patient had dengue virus
      (DENV) IgG and IgM antibodies but pan-flavivirus RT-PCR and subsequent sequencing
      showed presence of ZIKV RNA in urine. Recent association of ZIKV with
      microcephaly highlights the need for laboratory differentiation of ZIKV from DENV
      infection and the circulation of ZIKV in areas outside its currently known
      distribution range.
FAU - Korhonen, Essi Marjana
AU  - Korhonen EM
AD  - Department of Virology, Medicum, Faculty of Medicine, University of Helsinki,
      Helsinki, Finland.
FAU - Huhtamo, Eili
AU  - Huhtamo E
FAU - Smura, Teemu
AU  - Smura T
FAU - Kallio-Kokko, Hannimari
AU  - Kallio-Kokko H
FAU - Raassina, Markku
AU  - Raassina M
FAU - Vapalahti, Olli
AU  - Vapalahti O
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Sweden
TA  - Euro Surveill
JT  - Euro surveillance : bulletin Europeen sur les maladies transmissibles = European 
      communicable disease bulletin
JID - 100887452
RN  - 0 (RNA, Viral)
SB  - IM
MH  - Adult
MH  - Dengue/*diagnosis
MH  - Dengue Virus/isolation & purification
MH  - Exanthema/etiology
MH  - Fever/diagnosis/etiology/virology
MH  - Finland
MH  - Humans
MH  - Indian Ocean Islands
MH  - Male
MH  - Molecular Sequence Data
MH  - RNA, Viral/genetics/isolation & purification
MH  - Reverse Transcriptase Polymerase Chain Reaction
MH  - Sequence Analysis, RNA
MH  - Travel
MH  - Zika Virus/genetics/*isolation & purification
MH  - Zika Virus Infection/*diagnosis/urine/virology
OTO - NOTNLM
OT  - Zika virus
OT  - emerging infectious diseases
OT  - flavivirus
OT  - mosquito-borne
OT  - traveller
EDAT- 2016/01/23 06:00
MHDA- 2016/05/27 06:00
CRDT- 2016/01/23 06:00
PHST- 2015/12/21 [received]
PHST- 2016/01/14 [accepted]
AID - 10.2807/1560-7917.ES.2016.21.2.30107 [doi]
AID - 30107 [pii]
PST - ppublish
SO  - Euro Surveill. 2016;21(2). doi: 10.2807/1560-7917.ES.2016.21.2.30107.
TY  - JOUR
AU  - Korhonen, Essi Marjana
AU  - Huhtamo, Eili
AU  - Smura, Teemu
AU  - Kallio-Kokko, Hannimari
AU  - Raassina, Markku
AU  - Vapalahti, Olli
PY  - 2016//
TI  - Zika virus infection in a traveller returning from the Maldives, June 2015.
T2  - Euro Surveill.
JO  - Euro surveillance : bulletin Europe?en sur les maladies transmissibles = European communicable disease bulletin
VL  - 21
IS  - 2
KW  - Adult
KW  - Dengue
KW  - Dengue Virus
KW  - Exanthema
KW  - Fever
KW  - Finland
KW  - Humans
KW  - Indian Ocean Islands
KW  - Male
KW  - Molecular Sequence Data
KW  - RNA, Viral
KW  - Reverse Transcriptase Polymerase Chain Reaction
KW  - Sequence Analysis, RNA
KW  - Travel
KW  - Zika Virus
KW  - Zika Virus Infection
N2  - We report a Zika virus (ZIKV) infection in a patient with fever and rash after returning to Finland from Maldives, June 2015. The patient had dengue virus (DENV) IgG and IgM antibodies but pan-flavivirus RT-PCR and subsequent sequencing showed presence of ZIKV RNA in urine. Recent association of ZIKV with microcephaly highlights the need for laboratory differentiation of ZIKV from DENV infection and the circulation of ZIKV in areas outside its currently known distribution range.
SN  - 1560-7917
UR  - http://dx.doi.org/10.2807/1560-7917.ES.2016.21.2.30107
UR  - http://www.ncbi.nlm.nih.gov/pubmed/26794427
ID  - Korhonen2016
ER  - 
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