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Environmental risk factors for autism spectrum disorders.

Abstract Autism spectrum disorders (ASD) are syndromes that are predominantly defined by behavioral features such as impaired social interactions, restricted verbal and nonverbal communication, and repetitive or stereotyped behavior. In the past few decades, the reported prevalence of ASD has increased dramatically. This growth can be partially explained by an increased level of awareness of the problem among professionals and better diagnostic methods. Nevertheless, underpinning causes of ASD have not yet been detailed and explained. It is suggested that rather than having a single causative factor, ASD pathogenesis is influenced by environmental or genetic factors, or a combination of both. The aims of this review are to describe the environmental risk factors associated with ASD so as to provide a reference basis for current and future clinical and experimental work.
PMID
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Authors

Mayor MeshTerms
Keywords

Air pollution

Autism spectrum disorder

Environment

Migration

Risk factors

Journal Title der nervenarzt
Publication Year Start




PMID- 27531204
OWN - NLM
STAT- MEDLINE
DA  - 20160817
DCOM- 20170321
LR  - 20170321
IS  - 1433-0407 (Electronic)
IS  - 0028-2804 (Linking)
VI  - 87
IP  - Suppl 2
DP  - 2016 Dec
TI  - Environmental risk factors for autism spectrum disorders.
PG  - 55-61
LID - 10.1007/s00115-016-0172-3 [doi]
AB  - BACKGROUND: Autism spectrum disorders (ASD) are syndromes that are predominantly 
      defined by behavioral features such as impaired social interactions, restricted
      verbal and nonverbal communication, and repetitive or stereotyped behavior. In
      the past few decades, the reported prevalence of ASD has increased dramatically. 
      This growth can be partially explained by an increased level of awareness of the 
      problem among professionals and better diagnostic methods. Nevertheless,
      underpinning causes of ASD have not yet been detailed and explained. It is
      suggested that rather than having a single causative factor, ASD pathogenesis is 
      influenced by environmental or genetic factors, or a combination of both. The
      aims of this review are to describe the environmental risk factors associated
      with ASD so as to provide a reference basis for current and future clinical and
      experimental work. MATERIALS AND METHODS: On the basis of a PubMed search, we
      review the existing knowledge on environmental factors associated with ASD.
      RESULTS: A series of environmental factors have been repeatedly reported as risk 
      factors for ASD in existing studies. CONCLUSION: Air pollution, organic
      toxicants, seasonal factors, psychological stress, migration, birth order, and
      nutrition may have a close relationship with the incidence of ASD.
FAU - Liu, L
AU  - Liu L
AD  - Xiangya Nursing School, Mental Health Institute of the Second Xiangya Hospital,
      Central South University, Changsha, China.
FAU - Zhang, D
AU  - Zhang D
AD  - Xiangya Nursing School, Mental Health Institute of the Second Xiangya Hospital,
      Central South University, Changsha, China.
FAU - Rodzinka-Pasko, J K
AU  - Rodzinka-Pasko JK
AD  - Division of Applied Medicine, University of Aberdeen, Aberdeen, UK.
FAU - Li, Y-M
AU  - Li YM
AD  - Xiangya Nursing School, Mental Health Institute of the Second Xiangya Hospital,
      Central South University, Changsha, China. [email protected]
AD  - Clinical Nursing Teaching and Research Section, the Second Xiangya Hospital,
      Central South University, 139 Middle Renmin Road, Changsha, 410011, China.
      [email protected]
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
TT  - Umweltrisikofaktoren fur Autismusspektrumstorungen.
PL  - Germany
TA  - Nervenarzt
JT  - Der Nervenarzt
JID - 0400773
SB  - IM
MH  - Air Pollution/*statistics & numerical data
MH  - Autism Spectrum Disorder/diagnosis/*epidemiology/psychology
MH  - Birth Order/psychology
MH  - Causality
MH  - Comorbidity
MH  - Emigration and Immigration/*statistics & numerical data
MH  - Environmental Illness/*epidemiology
MH  - Evidence-Based Medicine
MH  - Humans
MH  - Incidence
MH  - Nutrition Disorders/*epidemiology
MH  - Risk Factors
MH  - Seasons
MH  - Stress, Psychological/*epidemiology/psychology
OTO - NOTNLM
OT  - *Air pollution
OT  - *Autism spectrum disorder
OT  - *Environment
OT  - *Migration
OT  - *Risk factors
EDAT- 2016/08/18 06:00
MHDA- 2017/03/23 06:00
CRDT- 2016/08/18 06:00
AID - 10.1007/s00115-016-0172-3 [doi]
AID - 10.1007/s00115-016-0172-3 [pii]
PST - ppublish
SO  - Nervenarzt. 2016 Dec;87(Suppl 2):55-61. doi: 10.1007/s00115-016-0172-3.

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