PMID- 28178163
OWN - NLM
STAT- MEDLINE
DA - 20170208
DCOM- 20170227
LR - 20170227
IS - 1536-5964 (Electronic)
IS - 0025-7974 (Linking)
VI - 96
IP - 6
DP - 2017 Feb
TI - The significance of diffusion tensor magnetic resonance imaging for patients with
nasopharyngeal carcinoma and trigeminal nerve invasion.
PG - e6072
LID - 10.1097/MD.0000000000006072 [doi]
AB - To investigate the significance of diffusion tensor imaging (DTI) for patients
with nasopharyngeal carcinoma (NPC) and trigeminal nerve invasion.Fifty-two
patients with NPC and unilateral infringement and 30 healthy controls were
recruited for our study. Routine magnetic resonance imaging (MRI) and DTI were
performed for all participants. Within-group and between-group comparisons of DTI
metrics, including fractional anisotropy (FA) and the apparent diffusion
coefficient (ADC) of the third (V3) branch of the bilateral trigeminal nerves of
all participants, were carried out.The FA and ADC values on the affected sides of
patients revealed a significant decrease and increase, respectively, when
compared with those on the unaffected sides of patients and the healthy controls
(P = 0.000 for all), whereas there were no significant differences in DTI metrics
between both sides of healthy controls or between the unaffected sides of
patients and the healthy controls (P = 0.930, 0.580, 0.095, and 0.360,
respectively). The decreasing FA rate on the affected sides of patients
correlated negatively with the increasing ADC rate (r = -0.675, P = 0.000).DTI
can quantitatively evaluate microstructural abnormalities of the V3 branch of the
trigeminal nerve in patients with NPC, which is important for the early detection
of trigeminal nerve invasion to achieve a precise T classification, assess
prognosis, and guide treatment.
FAU - Li, Tian
AU - Li T
AD - aDepartment of Radiology, Sun Yat-sen University Cancer Center, State Key
Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer
Medicine bDepartment of Medical Statistics and Epidemiology, School of Public
Health, Sun Yat-sen University, Guangzhou, Guangdong, People's Republic of China.
FAU - Sheng, Li
AU - Sheng L
FAU - Chunyan, Cui
AU - Chunyan C
FAU - Haoqiang, He
AU - Haoqiang H
FAU - Kangqiang, Peng
AU - Kangqiang P
FAU - Xiao, Gong
AU - Xiao G
FAU - Lizhi, Liu
AU - Lizhi L
LA - eng
PT - Journal Article
PT - Observational Study
PL - United States
TA - Medicine (Baltimore)
JT - Medicine
JID - 2985248R
RN - Nasopharyngeal carcinoma
SB - AIM
SB - IM
MH - Adult
MH - Anisotropy
MH - Diffusion Tensor Imaging/methods
MH - Female
MH - Humans
MH - Magnetic Resonance Imaging
MH - Male
MH - Middle Aged
MH - Nasopharyngeal Neoplasms/*diagnostic imaging/*pathology
MH - Trigeminal Nerve/*growth & development/*pathology
PMC - PMC5313020
EDAT- 2017/02/09 06:00
MHDA- 2017/02/28 06:00
CRDT- 2017/02/09 06:00
AID - 10.1097/MD.0000000000006072 [doi]
AID - 00005792-201702100-00044 [pii]
PST - ppublish
SO - Medicine (Baltimore). 2017 Feb;96(6):e6072. doi: 10.1097/MD.0000000000006072.