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Orbital apex syndrome as a complication of herpes zoster ophthalmicus.

Abstract Orbital apex syndrome is a rare neuro-ophthalmic manifestation of herpes zoster virus infection. We report one such case with favourable outcome in an immunocompetent patient. A 60-year-old woman presented with rash in the dermatome of the left ophthalmic nerve (V1), followed by sudden loss of vision with complete left-sided external and internal ophthalmoplegia. MRI of brain and orbits with contrast revealed optic perineuritis and myositis without intracranial involvement confirming the diagnosis of orbital apex syndrome. Functional visual recovery was achieved after a course of intravenous and oral steroids under antiviral cover over a follow-up period of 3 months.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title bmj case reports
Publication Year Start




PMID- 28237946
OWN - NLM
STAT- MEDLINE
DA  - 20170226
DCOM- 20170310
LR  - 20170310
IS  - 1757-790X (Electronic)
IS  - 1757-790X (Linking)
VI  - 2017
DP  - 2017 Feb 24
TI  - Orbital apex syndrome as a complication of herpes zoster ophthalmicus.
LID - bcr2016217382 [pii]
LID - 10.1136/bcr-2016-217382 [doi]
AB  - Orbital apex syndrome is a rare neuro-ophthalmic manifestation of herpes zoster
      virus infection. We report one such case with favourable outcome in an
      immunocompetent patient. A 60-year-old woman presented with rash in the dermatome
      of the left ophthalmic nerve (V1), followed by sudden loss of vision with
      complete left-sided external and internal ophthalmoplegia. MRI of brain and
      orbits with contrast revealed optic perineuritis and myositis without
      intracranial involvement confirming the diagnosis of orbital apex syndrome.
      Functional visual recovery was achieved after a course of intravenous and oral
      steroids under antiviral cover over a follow-up period of 3 months.
CI  - 2017 BMJ Publishing Group Ltd.
FAU - Chandrasekharan, Anjali
AU  - Chandrasekharan A
AD  - Department of Paediatric and Neuro-ophthalmology, Child Sight Institute, L V
      Prasad Eye Institute, Hyderabad, India.
FAU - Gandhi, Uppal
AU  - Gandhi U
AD  - Department of Paediatric and Neuro-ophthalmology, Child Sight Institute, L V
      Prasad Eye Institute, Hyderabad, India.
FAU - Badakere, Akshay
AU  - Badakere A
AD  - Department of Paediatric and Neuro-ophthalmology, Child Sight Institute, L V
      Prasad Eye Institute, Hyderabad, India.
FAU - Sangwan, Virender
AU  - Sangwan V
AUID- ORCID: http://orcid.org/0000-0002-8229-4158
AD  - Centre for Ocular Regeneration, L V Prasad Eye Institute, Hyderabad, India.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20170224
PL  - England
TA  - BMJ Case Rep
JT  - BMJ case reports
JID - 101526291
SB  - IM
MH  - Female
MH  - Herpes Zoster Ophthalmicus/*complications/drug therapy
MH  - Humans
MH  - Middle Aged
MH  - Myositis/diagnostic imaging/*virology
MH  - Ophthalmoplegia/*virology
MH  - Optic Neuritis/diagnostic imaging/*virology
MH  - Syndrome
MH  - Vision Disorders/*virology
EDAT- 2017/02/27 06:00
MHDA- 2017/03/11 06:00
CRDT- 2017/02/27 06:00
AID - bcr-2016-217382 [pii]
AID - 10.1136/bcr-2016-217382 [doi]
PST - epublish
SO  - BMJ Case Rep. 2017 Feb 24;2017. pii: bcr2016217382. doi: 10.1136/bcr-2016-217382.

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