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Haemophagocytic syndrome in an adult suffering from pyrexia of unknown origin: an uncommon presentation of tuberculosis: a case report.

Abstract Tuberculosis is common, can involve various organs of the body and may have diverse presentations. Haemophagocytic syndrome is one of the rare presentations of tuberculosis carrying a very high mortality. Early detection and institution of anti-tuberculosis medications can be life-saving.
PMID
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Authors

Mayor MeshTerms
Keywords

Case report

Haemophagocytic syndrome

Pyrexia of unknown origin

Tuberculosis

Journal Title bmc research notes
Publication Year Start




PMID- 28241857
OWN - NLM
STAT- MEDLINE
DA  - 20170228
DCOM- 20170317
LR  - 20170317
IS  - 1756-0500 (Electronic)
IS  - 1756-0500 (Linking)
VI  - 10
IP  - 1
DP  - 2017 Feb 27
TI  - Haemophagocytic syndrome in an adult suffering from pyrexia of unknown origin: an
      uncommon presentation of tuberculosis: a case report.
PG  - 110
LID - 10.1186/s13104-017-2434-y [doi]
AB  - BACKGROUND: Tuberculosis is common, can involve various organs of the body and
      may have diverse presentations. Haemophagocytic syndrome is one of the rare
      presentations of tuberculosis carrying a very high mortality. Early detection and
      institution of anti-tuberculosis medications can be life-saving. CASE
      PRESENTATION: A 23-year-old Bengali man presented with prolonged fever, weight
      loss, hepatosplenomegaly, pancytopenia and altered liver function. He had high
      erythrocyte sedimentation rate, positive tuberculin test, granuloma in liver
      biopsy, and haemophagocytosis was evidenced by histopathological examination of
      bone marrow. He recovered with anti-tuberculosis therapy. CONCLUSION: This case
      demonstrates that consideration of tuberculosis as an underlying cause of
      haemophagocytic syndrome could be rewarding and life-saving in this rapidly fatal
      condition.
FAU - Haque, Wasim Md Mohosin Ul
AU  - Haque WM
AD  - Department of Nephrology and Dialysis, Bangladesh Institute of Research and
      Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) General
      Hospital, Dhaka, 1000, Bangladesh. [email protected]
FAU - Shuvo, Md Erfanur Rahman
AU  - Shuvo ME
AD  - Department of Nephrology and Dialysis, Bangladesh Institute of Research and
      Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) General
      Hospital, Dhaka, 1000, Bangladesh.
FAU - Rahim, Muhammad Abdur
AU  - Rahim MA
AD  - Department of Nephrology and Dialysis, Bangladesh Institute of Research and
      Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) General
      Hospital, Dhaka, 1000, Bangladesh.
FAU - Mitra, Palash
AU  - Mitra P
AD  - Department of Nephrology and Dialysis, Bangladesh Institute of Research and
      Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) General
      Hospital, Dhaka, 1000, Bangladesh.
FAU - Samad, Tabassum
AU  - Samad T
AD  - Department of Nephrology and Dialysis, Bangladesh Institute of Research and
      Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM) General
      Hospital, Dhaka, 1000, Bangladesh.
FAU - Haque, Jalaluddin Ashraful
AU  - Haque JA
AD  - Ibrahim Medical College, Shahbag, Dhaka, 1000, Bangladesh.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20170227
PL  - England
TA  - BMC Res Notes
JT  - BMC research notes
JID - 101462768
RN  - 0 (Antitubercular Agents)
SB  - IM
MH  - Antitubercular Agents/therapeutic use
MH  - Diagnosis, Differential
MH  - Fever of Unknown Origin/*etiology/prevention & control
MH  - Humans
MH  - Lymphohistiocytosis, Hemophagocytic/*etiology/prevention & control
MH  - Male
MH  - Treatment Outcome
MH  - Tuberculosis/*complications/*diagnosis/drug therapy
MH  - Young Adult
PMC - PMC5327568
OTO - NOTNLM
OT  - *Case report
OT  - *Haemophagocytic syndrome
OT  - *Pyrexia of unknown origin
OT  - *Tuberculosis
EDAT- 2017/03/01 06:00
MHDA- 2017/03/18 06:00
CRDT- 2017/03/01 06:00
PHST- 2016/08/02 [received]
PHST- 2017/02/16 [accepted]
AID - 10.1186/s13104-017-2434-y [doi]
AID - 10.1186/s13104-017-2434-y [pii]
PST - epublish
SO  - BMC Res Notes. 2017 Feb 27;10(1):110. doi: 10.1186/s13104-017-2434-y.

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