PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

Correlation between Tear Osmolarity and Other Ocular Surface Parameters in Primary Sjögren's Syndrome.

Abstract To investigate the relationships between tear osmolarity and other ocular surface parameters and to determine the diagnostic value of tear osmolarity in primary Sjögren's syndrome (SS) using tear film break-up time, Schirmer I test, and cornea/conjunctiva staining.
PMID
Related Publications

Analysis of tear cytokines and clinical correlations in Sjögren syndrome dry eye patients and non-Sjögren syndrome dry eye patients.

Tear film osmolarity in ocular mucous membrane pemphigoid.

Evaluation of tear osmolarity in non-Sjögren and Sjögren syndrome dry eye patients with the TearLab system.

Tear osmolarity in Sjögren syndrome.

Tear osmolarity measurements in dry eye related to primary Sjögren's syndrome.

Authors

Mayor MeshTerms
Keywords

Dry eye syndrome

Sjögren's syndrome

Tear film osmolarity

Journal Title korean journal of ophthalmology : kjo
Publication Year Start




PMID- 28243020
OWN - NLM
STAT- MEDLINE
DA  - 20170228
DCOM- 20170314
LR  - 20170314
IS  - 2092-9382 (Electronic)
IS  - 1011-8942 (Linking)
VI  - 31
IP  - 1
DP  - 2017 Feb
TI  - Correlation between Tear Osmolarity and Other Ocular Surface Parameters in
      Primary Sjogren's Syndrome.
PG  - 25-31
LID - 10.3341/kjo.2017.31.1.25 [doi]
AB  - PURPOSE: To investigate the relationships between tear osmolarity and other
      ocular surface parameters and to determine the diagnostic value of tear
      osmolarity in primary Sjogren's syndrome (SS) using tear film break-up time,
      Schirmer I test, and cornea/conjunctiva staining. METHODS: We included 310 eyes
      of 155 patients diagnosed with dry eye disease (39 primary SS and 116 non-Sjogren
      dry eye disease) at Seoul St. Mary's Hospital from August 2010 to January 2015.
      All subjects completed the Ocular Surface Disease Index (OSDI) questionnaire and 
      underwent ocular examinations including tear osmolarity (TearLab Osmolarity
      System), Schirmer I test, slit lamp examination for tear film break-up time, and 
      corneal and conjunctival fluorescein staining. We used the mean value of both
      eyes for all parameters. Fluorescein staining was assessed using the Sjogren's
      International Collaborative Clinical Alliance ocular staining score (OSS).
      RESULTS: In primary SS patients (n = 39), the mean subject age was 52.5 +/- 11.9 
      years, and 94.9% of the subjects were women. Mean tear osmolarity in SS was 311.1
      +/- 16.4 mOsm/L, with 16 (41.0%) subjects having values >/=316 mOsm/L. In SS,
      there was a positive correlation between mean tear osmolarity and OSDI score (rho
      = 0.405, p = 0.011) and OSS (rho = 0.592, p < 0.001). There was a negative
      correlation between mean tear osmolarity and the Schirmer I test (rho = -0.625, p
      < 0.001). There was no significant correlation between mean tear osmolarity and
      tear film break-up time in SS (rho = 0.110, p = 0.505). CONCLUSIONS: Tear
      osmolarity measurements using the TearLab Osmolarity System can reflect both
      symptom severity (OSDI) and objective signs (Schirmer test and OSS) in SS.
FAU - Kim, Mirinae
AU  - Kim M
AD  - Department of Ophthalmology and Visual Science, Yeouido St. Mary's Hospital,
      College of Medicine, The Catholic University of Korea, Seoul, Korea.
FAU - Kim, Hyun Seung
AU  - Kim HS
AD  - Department of Ophthalmology and Visual Science, Yeouido St. Mary's Hospital,
      College of Medicine, The Catholic University of Korea, Seoul, Korea.
FAU - Na, Kyung-Sun
AU  - Na KS
AD  - Department of Ophthalmology and Visual Science, Yeouido St. Mary's Hospital,
      College of Medicine, The Catholic University of Korea, Seoul, Korea.
LA  - eng
PT  - Journal Article
DEP - 20170202
PL  - Korea (South)
TA  - Korean J Ophthalmol
JT  - Korean journal of ophthalmology : KJO
JID - 8804513
SB  - IM
MH  - Adult
MH  - Conjunctiva/diagnostic imaging/*metabolism
MH  - Cornea/diagnostic imaging/*metabolism
MH  - Cross-Sectional Studies
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Osmolar Concentration
MH  - Prospective Studies
MH  - Sjogren's Syndrome/diagnosis/*metabolism
MH  - Surveys and Questionnaires
MH  - Tears/*chemistry
MH  - Young Adult
PMC - PMC5327171
OTO - NOTNLM
OT  - Dry eye syndrome
OT  - Sjogren's syndrome
OT  - Tear film osmolarity
COI - Conflict of Interest: No potential conflict of interest relevant to this article 
      was reported.
EDAT- 2017/03/01 06:00
MHDA- 2017/03/16 06:00
CRDT- 2017/03/01 06:00
PHST- 2016/06/23 [received]
PHST- 2016/11/01 [accepted]
AID - 10.3341/kjo.2017.31.1.25 [doi]
PST - ppublish
SO  - Korean J Ophthalmol. 2017 Feb;31(1):25-31. doi: 10.3341/kjo.2017.31.1.25. Epub
      2017 Feb 2.

<?xml version="1.0" encoding="UTF-8"?>
<b:Sources SelectedStyle="" xmlns:b="http://schemas.openxmlformats.org/officeDocument/2006/bibliography"  xmlns="http://schemas.openxmlformats.org/officeDocument/2006/bibliography" >
</b:Sources>