PubTransformer

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PMID- 28243024
OWN - NLM
STAT- MEDLINE
DA  - 20170228
DCOM- 20170314
LR  - 20170314
IS  - 2092-9382 (Electronic)
IS  - 1011-8942 (Linking)
VI  - 31
IP  - 1
DP  - 2017 Feb
TI  - Outcomes of Cataract Surgery Following Treatment for Retinoblastoma.
PG  - 52-57
LID - 10.3341/kjo.2017.31.1.52 [doi]
AB  - PURPOSE: To evaluate the long-term visual outcomes and complications of cataract 
      surgery in eyes previously treated for retinoblastoma. METHODS: We reviewed the
      medical records of patients who underwent cataract extraction and intraocular
      lens implantation at Seoul National University Children's Hospital for a
      secondary cataract that developed after retinoblastoma treatment. RESULTS: During
      the period between 1990 and 2014, 208 eyes of 147 patients received eye-salvaging
      treatment (radiotherapy, chemotherapy, and local therapy) for retinoblastoma at
      Seoul National University Children's Hospital. Among these eyes, a secondary
      cataract was detected in 17 eyes of 14 patients, and five eyes of five patients
      underwent cataract surgery. The median age of cataract formation was 97 months
      (range, 38 to 153 months). The medial interval between the diagnosis of
      retinoblastoma and cataract formation was 79 months (range, 29 to 140 months).
      All patients received posterior chamber intraocular lens insertion after
      irrigation and aspiration of the lens through a scleral tunnel incision. Anterior
      vitrectomy and posterior capsulotomy were performed in two eyes and a laser
      capsulotomy was subsequently performed in one eye. No intraoperative and
      postoperative complications occurred. The median follow-up after surgery was 36
      months (range, 14 to 47 months). The final best corrected visual acuities were
      improved in all five eyes. No intraocular tumor recurrences or metastases
      occurred. CONCLUSIONS: After retinoblastoma regression, cataract extraction in
      our series was not associated with tumor recurrence or metastasis. Visual
      improvement was noted in every patient.
FAU - Kim, Hyeong Min
AU  - Kim HM
AD  - Department of Ophthalmology, Seoul National University College of Medicine,
      Seoul, Korea.; Department of Ophthalmology, Seoul National University Hospital,
      Seoul, Korea.
FAU - Lee, Byung Joo
AU  - Lee BJ
AD  - Department of Ophthalmology, Seoul National University College of Medicine,
      Seoul, Korea.; Fight against Angiogenesis-Related Blindness (FARB) Laboratory,
      Clinical Research Institute, Seoul National University Hospital, Seoul, Korea.
FAU - Kim, Jeong Hun
AU  - Kim JH
AD  - Department of Ophthalmology, Seoul National University College of Medicine,
      Seoul, Korea.; Fight against Angiogenesis-Related Blindness (FARB) Laboratory,
      Clinical Research Institute, Seoul National University Hospital, Seoul, Korea.
FAU - Yu, Young Suk
AU  - Yu YS
AD  - Department of Ophthalmology, Seoul National University College of Medicine,
      Seoul, Korea.; Department of Ophthalmology, Seoul National University Hospital,
      Seoul, Korea.; Fight against Angiogenesis-Related Blindness (FARB) Laboratory,
      Clinical Research Institute, Seoul National University Hospital, Seoul, Korea.
LA  - eng
PT  - Journal Article
DEP - 20170202
PL  - Korea (South)
TA  - Korean J Ophthalmol
JT  - Korean journal of ophthalmology : KJO
JID - 8804513
SB  - IM
MH  - Cataract/*etiology
MH  - Cataract Extraction/*methods
MH  - Child, Preschool
MH  - Combined Modality Therapy/adverse effects
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Infant
MH  - Male
MH  - Retinal Neoplasms/*therapy
MH  - Retinoblastoma/*therapy
MH  - Retrospective Studies
MH  - Time Factors
MH  - Treatment Outcome
PMC - PMC5327175
OTO - NOTNLM
OT  - Cataract surgery
OT  - Chemotherapy
OT  - Eye salvage
OT  - Radiotherapy
OT  - Retinoblastoma
COI - Conflict of Interest: No potential conflict of interest relevant to this article 
      was reported.
EDAT- 2017/03/01 06:00
MHDA- 2017/03/16 06:00
CRDT- 2017/03/01 06:00
PHST- 2015/11/02 [received]
PHST- 2016/02/03 [accepted]
AID - 10.3341/kjo.2017.31.1.52 [doi]
PST - ppublish
SO  - Korean J Ophthalmol. 2017 Feb;31(1):52-57. doi: 10.3341/kjo.2017.31.1.52. Epub
      2017 Feb 2.

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