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Systemic Amyloidosis Model on Young Mice.

Abstract Subcutaneous daily injection (with neglect of aseptics) of 0.5 ml solution of soybean cream substitute (10% volume in distilled water) during 30 days caused systemic amyloidosis in 30-day-old mice. All the known methods for induction of systemic amyloidosis are based on the use of old animals, as senile tissue bradytrophy allows effective simulation of amyloidosis.
PMID
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Authors

Mayor MeshTerms

Disease Models, Animal

Keywords

amyloidosis model

young mice

Journal Title bulletin of experimental biology and medicine
Publication Year Start




PMID- 28243908
OWN - NLM
STAT- MEDLINE
DA  - 20170228
DCOM- 20170315
LR  - 20170315
IS  - 1573-8221 (Electronic)
IS  - 0007-4888 (Linking)
VI  - 162
IP  - 4
DP  - 2017 Feb
TI  - Systemic Amyloidosis Model on Young Mice.
PG  - 520-523
LID - 10.1007/s10517-017-3652-y [doi]
AB  - Subcutaneous daily injection (with neglect of aseptics) of 0.5 ml solution of
      soybean cream substitute (10% volume in distilled water) during 30 days caused
      systemic amyloidosis in 30-day-old mice. All the known methods for induction of
      systemic amyloidosis are based on the use of old animals, as senile tissue
      bradytrophy allows effective simulation of amyloidosis.
FAU - Kozlov, V A
AU  - Kozlov VA
AD  - Department of Medical Biology with a Course of Microbiology and Virology,
      Cheboksary, Russia. [email protected]
FAU - Sapozhnikov, S P
AU  - Sapozhnikov SP
AD  - Department of Medical Biology with a Course of Microbiology and Virology,
      Cheboksary, Russia.
FAU - Karyshev, P B
AU  - Karyshev PB
AD  - Department of Common, Clinical Pathology and Forensic Medicine, I. N. Ulyanov
      Chuvash State University, Cheboksary, Russia.
FAU - Sheptukhina, A I
AU  - Sheptukhina AI
AD  - Department of Medical Biology with a Course of Microbiology and Virology,
      Cheboksary, Russia.
FAU - Nikolaeva, O V
AU  - Nikolaeva OV
AD  - Department of Medical Biology with a Course of Microbiology and Virology,
      Cheboksary, Russia.
LA  - eng
PT  - Journal Article
DEP - 20170227
PL  - United States
TA  - Bull Exp Biol Med
JT  - Bulletin of experimental biology and medicine
JID - 0372557
RN  - 0 (Amyloid)
RN  - 0 (Emulsifying Agents)
RN  - 0 (High Fructose Corn Syrup)
RN  - 36-88-4 (Carotenoids)
RN  - 7631-86-9 (Silicon Dioxide)
RN  - 8001-22-7 (Soybean Oil)
SB  - IM
MH  - Age of Onset
MH  - Amyloid/*ultrastructure
MH  - Amyloidosis/chemically induced/metabolism/*pathology
MH  - Animals
MH  - Carotenoids/chemistry
MH  - *Disease Models, Animal
MH  - Emulsifying Agents/chemistry
MH  - High Fructose Corn Syrup/chemistry
MH  - Injections, Subcutaneous
MH  - Kidney/metabolism/pathology/ultrastructure
MH  - Liver/metabolism/pathology/ultrastructure
MH  - Male
MH  - Mice
MH  - Nanoparticles/administration & dosage/*toxicity
MH  - Silicon Dioxide/chemistry
MH  - Skin Cream/administration & dosage/*toxicity
MH  - Soybean Oil/chemistry
MH  - Spleen/metabolism/pathology/ultrastructure
OTO - NOTNLM
OT  - amyloidosis model
OT  - young mice
EDAT- 2017/03/01 06:00
MHDA- 2017/03/16 06:00
CRDT- 2017/03/01 06:00
PHST- 2015/08/10 [received]
AID - 10.1007/s10517-017-3652-y [doi]
AID - 10.1007/s10517-017-3652-y [pii]
PST - ppublish
SO  - Bull Exp Biol Med. 2017 Feb;162(4):520-523. doi: 10.1007/s10517-017-3652-y. Epub 
      2017 Feb 27.

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