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Can imaging modalities be used as follow-up criteria after brucellar sacroiliitis treatment?

Abstract This study aimed to identify a follow-up modality that can be used to evaluate therapeutic responses in patients receiving treatment for brucellar sacroillitis and to determine whether antibiotherapy can be stopped.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title journal of infection in developing countries
Publication Year Start




PMID- 28248672
OWN - NLM
STAT- MEDLINE
DA  - 20170301
DCOM- 20170315
LR  - 20170315
IS  - 1972-2680 (Electronic)
IS  - 1972-2680 (Linking)
VI  - 11
IP  - 2
DP  - 2017 Feb 28
TI  - Can imaging modalities be used as follow-up criteria after brucellar sacroiliitis
      treatment?
PG  - 123-128
LID - 10.3855/jidc.6599 [doi]
AB  - INTRODUCTION: This study aimed to identify a follow-up modality that can be used 
      to evaluate therapeutic responses in patients receiving treatment for brucellar
      sacroillitis and to determine whether antibiotherapy can be stopped. METHODOLOGY:
      A total of 32 patients with sacroiliac joint involvement demonstrated via
      magnetic resonance imaging or bone scintigraphy were followed up and treated.
      Patients received 200 mg/day of doxycycline and 600-900 mg/day of rifampicin for 
      3-21 months, and 1 g/day of streptomycin for 21 days. RESULTS: The mean age of
      the 32 patients involved was 21.81+/-4.09. In total, 10/32 patients did not
      complete therapy, and the remaining 22 patients received combination antibiotic
      treatment for a mean of 8.95+/-4.34 months. Of the 22 patients, 15 underwent MRI,
      and 7 of them did not consent to MRI. Similarly, 17 patients were followed up by 
      bone scintigraphy, and 5 patients did not have scintigraphy results. In 9/17
      patients followed up with bone scintigraphy, sacroiliitis findings were found to 
      reduce after a mean of 7.44+/-3.71 months, whereas in 12/15 patients on whom MRI 
      was performed, there were no active sacroiliitis findings for a mean of
      6.95+/-2.83 months. CONCLUSIONS: While active involvement findings in bone
      scintigraphy were observed for a longer period in scintigraphy images, active
      sacroiliitis findings disappeared in a relatively shorter period of time with
      MRI. Therefore, we have demonstrated that high-resolution MRI is a very sensitive
      technique compared to scintigraphy.
FAU - Bilgeturk, Aybars
AU  - Bilgeturk A
AD  - Gulhane Military Medical Academy and School of Medicine, General Tevfik Saglam
      Street, Ankara, Turkey. [email protected]
FAU - Gul, Hanefi Cem
AU  - Gul HC
FAU - Karakas, Ahmet
AU  - Karakas A
FAU - Mert, Gurkan
AU  - Mert G
FAU - Artuk, Cumhur
AU  - Artuk C
FAU - Eyigun, Can Polat
AU  - Eyigun CP
LA  - eng
PT  - Journal Article
DEP - 20170228
PL  - Italy
TA  - J Infect Dev Ctries
JT  - Journal of infection in developing countries
JID - 101305410
RN  - 0 (Anti-Bacterial Agents)
RN  - N12000U13O (Doxycycline)
RN  - VJT6J7R4TR (Rifampin)
RN  - Y45QSO73OB (Streptomycin)
SB  - IM
MH  - Adult
MH  - Anti-Bacterial Agents/*administration & dosage
MH  - Brucellosis/*diagnostic imaging/drug therapy
MH  - Doxycycline/administration & dosage
MH  - Drug Monitoring/*methods
MH  - Female
MH  - Follow-Up Studies
MH  - Humans
MH  - Magnetic Resonance Imaging/*methods
MH  - Male
MH  - Radionuclide Imaging/*methods
MH  - Retrospective Studies
MH  - Rifampin/administration & dosage
MH  - Sacroiliitis/*diagnostic imaging/*drug therapy
MH  - Streptomycin/administration & dosage
MH  - Young Adult
EDAT- 2017/03/02 06:00
MHDA- 2017/03/16 06:00
CRDT- 2017/03/02 06:00
PHST- 2015/01/20 [received]
PHST- 2015/12/14 [accepted]
PHST- 2015/10/21 [revised]
PST - epublish
SO  - J Infect Dev Ctries. 2017 Feb 28;11(2):123-128. doi: 10.3855/jidc.6599.

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