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PMID- 28248682
DA  - 20170301
DCOM- 20170315
LR  - 20170315
IS  - 1972-2680 (Electronic)
IS  - 1972-2680 (Linking)
VI  - 11
IP  - 2
DP  - 2017 Feb 28
TI  - Causes of visual impairment in patients with ocular toxoplasmosis.
PG  - 192-195
LID - 10.3855/jidc.7138 [doi]
AB  - INTRODUCTION: The aim of this study was to report the causes of visual impairment
      in patients with the classic clinical presentation of ocular toxoplasmosis (OT). 
      METHODOLOGY: Eight patients with OT underwent standardized ophthalmologic
      examination and fundus imaging. Macula and the lesions that could be visualized
      were evaluated by spectral domain optical coherence tomography (SOCT) at
      presentation. The scan acquisition protocols for SOCT included a radial line scan
      through the retinochoroiditis lesion, radial line macular scan, and horizontal
      volume scans at the macula. RESULTS: The mean age of the five (62.5%) women and
      three (37.5%) men was 25.7+/-7.6 years. The mean logMAR ETDRS best-corrected
      visual acuity was 0.45 (Snellen equivalent, 20/50). SOCT findings of macula were 
      normal in seven patients, and one patient had decreased retinal thickness from a 
      healed chorioretinitis at the fovea. Of eight patients, two had 3+ vitreous haze,
      four had 2+ vitreous haze, and two had 1+ vitreous haze at presentation. OCT
      scans revealed vitreous hyperreflective dots in all patients with different
      densities in different radial scans. Hyperreflective dots were denser in macular 
      scans of eyes in which the active lesion was closer to the fovea. CONCLUSIONS: In
      this study, visual impairment in majority of the patients was found to be related
      to vitreous cells and flare. Dense vitritis on macula scans and visual impairment
      were seen in the patients who had an active lesion closer to the fovea. SOCT may 
      provide objective data of the cellular load of the eyes with posterior segment
FAU - Sahinoglu Keskek, Nedime
AU  - Sahinoglu Keskek N
AD  - Adana Numune Training and Research Hospital, Adana, Turkey.
      [email protected]
FAU - Unal, Fikret
AU  - Unal F
FAU - Cevher, Selim
AU  - Cevher S
FAU - Keskek, Sakir Ozgur
AU  - Keskek SO
LA  - eng
PT  - Journal Article
DEP - 20170228
PL  - Italy
TA  - J Infect Dev Ctries
JT  - Journal of infection in developing countries
JID - 101305410
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - Macula Lutea/pathology
MH  - Male
MH  - Tomography
MH  - Toxoplasmosis, Ocular/*complications/diagnostic imaging/*pathology
MH  - Vision Disorders/*etiology
MH  - Vitreous Body/pathology
MH  - Young Adult
EDAT- 2017/03/02 06:00
MHDA- 2017/03/16 06:00
CRDT- 2017/03/02 06:00
PHST- 2015/05/14 [received]
PHST- 2015/07/13 [accepted]
PHST- 2015/07/10 [revised]
PST - epublish
SO  - J Infect Dev Ctries. 2017 Feb 28;11(2):192-195. doi: 10.3855/jidc.7138.

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