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Stroke Associated With Varicella Zoster Vasculopathy: A Clinicoradiological Profile of 3 Patients.

Abstract Varicella zoster (VZ) vasculopathy is a rare but well recognized cause of stroke. In the absence of zoster rash and infection in remote past, the disease can pose diagnostic challenge. We report 3 cases of anterior circulation stroke occurring in close temporal relation to VZ. Their clinical, radiologic, and angiographic features are discussed.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title the neurologist
Publication Year Start




PMID- 28248918
OWN - NLM
STAT- In-Process
DA  - 20170301
LR  - 20170301
IS  - 2331-2637 (Electronic)
IS  - 1074-7931 (Linking)
VI  - 22
IP  - 2
DP  - 2017 Mar
TI  - Stroke Associated With Varicella Zoster Vasculopathy: A Clinicoradiological
      Profile of 3 Patients.
PG  - 64-67
LID - 10.1097/NRL.0000000000000111 [doi]
AB  - INTRODUCTION: Varicella zoster (VZ) vasculopathy is a rare but well recognized
      cause of stroke. In the absence of zoster rash and infection in remote past, the 
      disease can pose diagnostic challenge. We report 3 cases of anterior circulation 
      stroke occurring in close temporal relation to VZ. Their clinical, radiologic,
      and angiographic features are discussed. CASE REPORT: Of the 3 patients, 2 had
      stroke within a span of 4 to 6 weeks of herpes zoster ophthalmicus while the
      third patient had zoster of cervical dermatome. Magnetic resonance imaging
      revealed acute subcortical infarcts in 2, while 1 patient showed acute on chronic
      infarct in left middle cerebral artery territory. The magnetic resonance
      angiography was abnormal in 2 patients while it was normal in third. All the
      patients were treated with acyclovir and antiplatelets with good recovery in 2.
      CONCLUSIONS: VZ associated vasculopathy may have diverse clinical profile and
      neuroimaging features. It should be considered as an important and treatable
      cause of stroke in appropriate clinical settings.
FAU - Maurya, Pradeep K
AU  - Maurya PK
AD  - Department of Neurology, Dr Ram Manohar Lohia Institute of Medical Sciences,
      Lucknow, India.
FAU - Kulshreshtha, Dinkar
AU  - Kulshreshtha D
FAU - Singh, Ajai K
AU  - Singh AK
FAU - Thacker, Anup K
AU  - Thacker AK
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Neurologist
JT  - The neurologist
JID - 9503763
EDAT- 2017/03/02 06:00
MHDA- 2017/03/02 06:00
CRDT- 2017/03/02 06:00
AID - 10.1097/NRL.0000000000000111 [doi]
AID - 00127893-201703000-00007 [pii]
PST - ppublish
SO  - Neurologist. 2017 Mar;22(2):64-67. doi: 10.1097/NRL.0000000000000111.

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