PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.




PMID- 28249912
OWN - NLM
STAT- MEDLINE
DA  - 20170302
DCOM- 20170313
LR  - 20170313
IS  - 1550-8080 (Electronic)
IS  - 0091-7370 (Linking)
VI  - 47
IP  - 1
DP  - 2017 Jan
TI  - Prognostic Evaluation of Neutrophil/Lymphocyte Ratio in Patients with Mycosis
      Fungoides.
PG  - 25-28
AB  - BACKGROUND: The role of inflammation has been established in cancer biology and
      the neutrophil to lymphocyte ratio postulated as a marker of systemic
      inflammatory response. The prognostic significance of neutrophil to lymphocyte
      ratio has never been explored in patients with mycosis fungoides. METHODS: Data
      from 119 mycosis fungoides (MF) patients, diagnosed between 1998 and 2015 at a
      single centre, were evaluated retrospectively. The prognostic influence of the
      neutrophil to lymphocyte ratio and other clinico-pathological factors including
      age, lactate dehydrogenase, stage of disease, beta-2-microglobulin levels, and
      total IgE levels were evaluated. RESULTS: The mean value of absolute neutrophil
      count and absolute lymphocyte count (ANC/ALC) ratio was 2.07+/-1.17 in the
      patient group, whereas it was 1.76+/-0.53 in the control group (P<0.05). An
      ANC/ALC value of 2.85 corresponded to the maximum combined sensitivity and
      specificity on the ROC curve. ANC/ALC ratios of 2.85 or higher at diagnosis were 
      positively correlated with elevated Beta-2-microglobulin (P=0.026), advanced
      disease stage, and disease progression (P=0.026, r=0.204) (P=0 .006, r=0.251)
      (P=0 .018, r=0.216). CONCLUSION: In the present study, we showed that a high
      ANC/ALC ratio at diagnosis of MF represents a simple, poor prognostic factor for 
      identifying high-risk patients with MF.
CI  - (c) 2017 by the Association of Clinical Scientists, Inc.
FAU - Cengiz, Fatma Pelin
AU  - Cengiz FP
AD  - Department of Dermatoveneorology, Bezmialem Vakif University, Bezmialem Vakif
      University Hospital, Istanbul, Turkey [email protected]
FAU - Emiroglu, Nazan
AU  - Emiroglu N
AD  - Department of Dermatoveneorology, Bezmialem Vakif University, Bezmialem Vakif
      University Hospital, Istanbul, Turkey.
FAU - Ozkaya, Dilek Biyik
AU  - Ozkaya DB
AD  - Department of Dermatoveneorology, Bezmialem Vakif University, Bezmialem Vakif
      University Hospital, Istanbul, Turkey.
FAU - Bahali, Anil Gulsel
AU  - Bahali AG
AD  - Department of Dermatoveneorology, Bezmialem Vakif University, Bezmialem Vakif
      University Hospital, Istanbul, Turkey.
FAU - Su, Ozlem
AU  - Su O
AD  - Department of Dermatoveneorology, Bezmialem Vakif University, Bezmialem Vakif
      University Hospital, Istanbul, Turkey.
FAU - Onsun, Nahide
AU  - Onsun N
AD  - Department of Dermatoveneorology, Bezmialem Vakif University, Bezmialem Vakif
      University Hospital, Istanbul, Turkey.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Ann Clin Lab Sci
JT  - Annals of clinical and laboratory science
JID - 0410247
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Child
MH  - Female
MH  - Humans
MH  - Leukocyte Count
MH  - Lymphocyte Count
MH  - Lymphocytes/*immunology
MH  - Male
MH  - Middle Aged
MH  - Mycosis Fungoides/*immunology/pathology
MH  - Neutrophils/*immunology
MH  - Prognosis
MH  - Young Adult
OTO - NOTNLM
OT  - Lymphocyte
OT  - Mycosis Fungoides
OT  - Neutrophil
OT  - Prognosis
OT  - Ratio
EDAT- 2017/03/03 06:00
MHDA- 2017/03/14 06:00
CRDT- 2017/03/03 06:00
AID - 47/1/25 [pii]
PST - ppublish
SO  - Ann Clin Lab Sci. 2017 Jan;47(1):25-28.

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