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Predictors of metabolic syndrome in first manic episode.

Abstract In the present study we aimed to investigate, whether an association between metabolic syndrome (MetS) and clinical features and affective temperaments exists or not in first manic episode of bipolar disorder (BD) and to clarify the prevalence and predictors of MetS.
PMID
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Authors

Mayor MeshTerms
Keywords

Affective temperament

Bipolar disorder

First episode mania

Metabolic syndrome

Journal Title asian journal of psychiatry
Publication Year Start




PMID- 28262145
OWN - NLM
STAT- MEDLINE
DA  - 20170306
DCOM- 20170314
LR  - 20170314
IS  - 1876-2026 (Electronic)
IS  - 1876-2018 (Linking)
VI  - 25
DP  - 2017 Feb
TI  - Predictors of metabolic syndrome in first manic episode.
PG  - 179-183
LID - S1876-2018(16)30117-4 [pii]
LID - 10.1016/j.ajp.2016.10.014 [doi]
AB  - OBJECTIVE: In the present study we aimed to investigate, whether an association
      between metabolic syndrome (MetS) and clinical features and affective
      temperaments exists or not in first manic episode of bipolar disorder (BD) and to
      clarify the prevalence and predictors of MetS. METHOD: A total of 150 patients
      who were received a diagnosis of bipolar disorder type I according to DSM-IV
      criteria and who were experiencing their first manic episode (FME) were screened 
      consecutively for inclusion. NCEP ATP III formulated an operational definition of
      MetS based on the presence of three or more of the following characteristics:
      abdominal obesity (waist circumference), hypertriglyceridemia, low HDL or being
      on an antilipidemic agent, high blood pressure or being on an antihypertensive
      agent, and fasting hyperglycemia or being on antiglycemic agent. The patients who
      had been in remission period for at least 8 weeks were evaluated with SKIP-TURK
      and TEMPS-A. Remission was defined as YMRS score <5. RESULTS: 37 (32.5%) patients
      had a MetS. Previous depressive episode, seasonality, negative family history and
      childhood trauma are determined as the predictors of MetS. Anxious and irritable 
      temperament scores were higher in MetS (+) patients. CONCLUSION: According to our
      results, links between MetS and BD may also have been predicted by genetic and
      environmental factors.
CI  - Copyright (c) 2016 Elsevier B.V. All rights reserved.
FAU - Kesebir, Sermin
AU  - Kesebir S
AD  - Uskudar University, NPIstanbul Neuropsychiatry Hospital, Istanbul, Turkey.
      Electronic address: [email protected]
FAU - Erdinc, Boray
AU  - Erdinc B
AD  - Uskudar University, NPIstanbul Neuropsychiatry Hospital, Istanbul, Turkey.
FAU - Tarhan, Nevzat
AU  - Tarhan N
AD  - Uskudar University, NPIstanbul Neuropsychiatry Hospital, Istanbul, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20161026
PL  - Netherlands
TA  - Asian J Psychiatr
JT  - Asian journal of psychiatry
JID - 101517820
SB  - IM
MH  - Adult
MH  - Bipolar Disorder/*epidemiology/psychology
MH  - Comorbidity
MH  - Cross-Sectional Studies
MH  - Female
MH  - Humans
MH  - Male
MH  - Metabolic Syndrome X/*epidemiology/psychology
MH  - Prevalence
MH  - Prognosis
MH  - Temperament/*physiology
MH  - Turkey/epidemiology
OTO - NOTNLM
OT  - Affective temperament
OT  - Bipolar disorder
OT  - First episode mania
OT  - Metabolic syndrome
EDAT- 2017/03/07 06:00
MHDA- 2017/03/16 06:00
CRDT- 2017/03/07 06:00
PHST- 2016/03/11 [received]
PHST- 2016/08/01 [revised]
PHST- 2016/10/10 [accepted]
AID - S1876-2018(16)30117-4 [pii]
AID - 10.1016/j.ajp.2016.10.014 [doi]
PST - ppublish
SO  - Asian J Psychiatr. 2017 Feb;25:179-183. doi: 10.1016/j.ajp.2016.10.014. Epub 2016
      Oct 26.

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