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Psychosis as a late manifestation of Sheehan's syndrome.

Abstract Sheehan's syndrome occurs as a result of ischemic pituitary necrosis due to severe postpartum haemorrhage. It is one of the most common causes of hypopituitarism in underdeveloped or developing countries. Characteristic manifestations include failure to lactate or to resume menses, genital and axillary hair loss, asthenia and weakness, fine wrinkles around the eyes and lips, signs of premature aging, dry skin, hypopigmentation and other evidence of hypopituitarism. Uncommonly it can present with psychosis. There are only few case reports of psychoses in patients with Sheehan's syndrome. Our case report illustrates the relationship between psychosis and Sheehan's syndrome. The treatment challenges in managing Sheehan's syndrome and psychosis are discussed.
PMID
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Authors

Mayor MeshTerms
Keywords

Glucocorticoids

Psychosis

Sheehan syndrome

Thyroxin

Journal Title asian journal of psychiatry
Publication Year Start




PMID- 28262158
OWN - NLM
STAT- MEDLINE
DA  - 20170306
DCOM- 20170314
LR  - 20170314
IS  - 1876-2026 (Electronic)
IS  - 1876-2018 (Linking)
VI  - 25
DP  - 2017 Feb
TI  - Psychosis as a late manifestation of Sheehan's syndrome.
PG  - 228-230
LID - S1876-2018(16)30473-7 [pii]
LID - 10.1016/j.ajp.2016.12.003 [doi]
AB  - Sheehan's syndrome occurs as a result of ischemic pituitary necrosis due to
      severe postpartum haemorrhage. It is one of the most common causes of
      hypopituitarism in underdeveloped or developing countries. Characteristic
      manifestations include failure to lactate or to resume menses, genital and
      axillary hair loss, asthenia and weakness, fine wrinkles around the eyes and
      lips, signs of premature aging, dry skin, hypopigmentation and other evidence of 
      hypopituitarism. Uncommonly it can present with psychosis. There are only few
      case reports of psychoses in patients with Sheehan's syndrome. Our case report
      illustrates the relationship between psychosis and Sheehan's syndrome. The
      treatment challenges in managing Sheehan's syndrome and psychosis are discussed.
CI  - Copyright (c) 2016. Published by Elsevier B.V.
FAU - Reddy, Mukku Shiva Shanker
AU  - Reddy MS
AD  - Department of Psychiatry, National Institute of Mental Health and Neuro Sciences,
      Bangalore, 560029, India. Electronic address: shivakmc55@gmail.com.
FAU - Nahar, Abhinav
AU  - Nahar A
AD  - Department of Psychiatry, National Institute of Mental Health and Neuro Sciences,
      Bangalore, 560029, India. Electronic address: abhinavnahar2002@gmail.com.
FAU - Thippeswamy, Harish
AU  - Thippeswamy H
AD  - Department of Psychiatry, National Institute of Mental Health and Neuro Sciences,
      Bangalore, 560029, India. Electronic address: docharisht@gmail.com.
FAU - Kumar, Chaturvedi Santosh
AU  - Kumar CS
AD  - Department of Psychiatry, National Institute of Mental Health and Neuro Sciences,
      Bangalore, 560029, India. Electronic address: skchatur@gmail.com.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20161207
PL  - Netherlands
TA  - Asian J Psychiatr
JT  - Asian journal of psychiatry
JID - 101517820
SB  - IM
MH  - Adult
MH  - Female
MH  - Humans
MH  - Hypopituitarism/*complications
MH  - Psychotic Disorders/*etiology
OTO - NOTNLM
OT  - *Glucocorticoids
OT  - *Psychosis
OT  - *Sheehan syndrome
OT  - *Thyroxin
EDAT- 2017/03/07 06:00
MHDA- 2017/03/16 06:00
CRDT- 2017/03/07 06:00
PHST- 2016/10/11 [received]
PHST- 2016/12/05 [accepted]
AID - S1876-2018(16)30473-7 [pii]
AID - 10.1016/j.ajp.2016.12.003 [doi]
PST - ppublish
SO  - Asian J Psychiatr. 2017 Feb;25:228-230. doi: 10.1016/j.ajp.2016.12.003. Epub 2016
      Dec 7.

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