PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.




PMID- 28266286
OWN - NLM
STAT- MEDLINE
DA  - 20170307
DCOM- 20170315
LR  - 20170315
IS  - 1473-5644 (Electronic)
IS  - 0022-2615 (Linking)
VI  - 66
IP  - 2
DP  - 2017 Feb
TI  - Genetic analyses of the fusion protein genes in human parainfluenza virus types 1
      and 3 among patients with acute respiratory infections in Eastern Japan from 2011
      to 2015.
PG  - 160-168
LID - 10.1099/jmm.0.000431 [doi]
AB  - PURPOSE: To genetically explore the fusion protein gene (F) in human
      parainfluenza virus type 1 (HPIV1) and type 3 (HPIV3) strains, we analysed them
      in patients with acute respiratory infections in Eastern Japan from 2011 to 2015.
      METHODOLOGY: We constructed phylogenetic trees based on the HPIV and HPIV3 F gene
      using the maximum likelihood method and conducted P-distance and selective
      pressure analyses. We also predicted the linear epitopes of the protein in the
      prototype strains. Furthermore, we mapped the amino acid substitutions of the
      proteins. RESULTS: Nineteen strains of HPIV1 and 53 strains of HPIV3 were
      detected among the clinical acute respiratory infection cases. The phylogenetic
      trees indicated that the HPIV1 and HPIV3 strains were classified into clusters II
      and III and cluster C, respectively. The P-distance values of the HPIV1 and HPIV3
      F genes were <0.03. Two positive selection sites were inferred in the HPIV1 (aa 8
      and aa 10), and one positive selection site was inferred in the HPIV3 (aa 108),
      but over 10 negative selection sites were inferred. Four epitopes were predicted 
      for the HPIV1 prototype strains, while five epitopes were predicted for the HPIV3
      prototype strain. A positive selection site (aa 108) or the HPIV3 F protein was
      involved in the predicted epitope. Additionally, we found that an amino acid
      substitution (R73K) in the LC76627 HPIV3 strain presumably may affect the
      resistance to neutralization by antibodies. CONCLUSION: The F gene of HPIV1 and
      HPIV3 was relatively well conserved in the eastern part of Japan during the
      investigation period.
FAU - Tsutsui, Rika
AU  - Tsutsui R
AD  - 1Aomori Prefecture Public Health and Environment Center, 1-1-1,
      Higashitsukurimichi, Aomori-shi, Aomori 030-8566, Japan 2Department of Pathologic
      Analysis, Division of Medical Life Sciences, Hirosaki University Graduate School 
      of Health Sciences, 66-1, Hon-cho, Hirosaki-shi, Aomori 036-8564, Japan.
FAU - Tsukagoshi, Hiroyuki
AU  - Tsukagoshi H
AD  - 3Gunma Prefectural Institute of Public Health and Environmental Sciences, 378
      Kamioki-machi, Maebashi-shi, Gunma 371-0052, Japan.
FAU - Nagasawa, Koo
AU  - Nagasawa K
AD  - 4Infectious Disease Surveillance Center, National Institute of Infectious
      Diseases, 4-7-1 Gakuen, Musashimurayama-shi, Tokyo 208-0011, Japan.
FAU - Takahashi, Masaki
AU  - Takahashi M
AD  - 5Research Institute for Environmental Sciences and Public Health of Iwate
      Prefecture, 1-11-16, Kitaiioka, Morioka-shi, Iwate 020-0857, Japan.
FAU - Matsushima, Yuki
AU  - Matsushima Y
AD  - 6Division of Virology, Kawasaki City Institute for Public Health, 3-25-13,
      Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa 210-0821, Japan.
FAU - Ryo, Akihide
AU  - Ryo A
AD  - 7Department of Molecular Biodefence Research, Yokohama City University Graduate
      School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama-shi, Kanagawa 236-0004,
      Japan.
FAU - Kuroda, Makoto
AU  - Kuroda M
AD  - 8Pathogen Genomics Center, National Institute of Infectious Diseases, 1-23-1
      Toyama, Shinjuku-ku, Tokyo 162-8640, Japan.
FAU - Takami, Hideki
AU  - Takami H
AD  - 2Department of Pathologic Analysis, Division of Medical Life Sciences, Hirosaki
      University Graduate School of Health Sciences, 66-1, Hon-cho, Hirosaki-shi,
      Aomori 036-8564, Japan.
FAU - Kimura, Hirokazu
AU  - Kimura H
AD  - 4Infectious Disease Surveillance Center, National Institute of Infectious
      Diseases, 4-7-1 Gakuen, Musashimurayama-shi, Tokyo 208-0011, Japan 7Department of
      Molecular Biodefence Research, Yokohama City University Graduate School of
      Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama-shi, Kanagawa 236-0004, Japan.
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Med Microbiol
JT  - Journal of medical microbiology
JID - 0224131
RN  - 0 (Epitopes)
RN  - 0 (RNA, Viral)
RN  - 0 (Viral Fusion Proteins)
RN  - 109300-94-9 (F protein, parainfluenza virus 3)
SB  - IM
MH  - Acute Disease
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Amino Acid Substitution
MH  - Child
MH  - Child, Preschool
MH  - Epitopes/genetics/metabolism
MH  - Female
MH  - Humans
MH  - Infant
MH  - Japan/epidemiology
MH  - Likelihood Functions
MH  - Male
MH  - Middle Aged
MH  - Parainfluenza Virus 1, Human/*genetics/isolation & purification
MH  - Parainfluenza Virus 3, Human/*genetics/isolation & purification
MH  - Phylogeny
MH  - RNA, Viral/genetics/isolation & purification
MH  - Respiratory Tract Infections/*epidemiology/virology
MH  - Respirovirus Infections/*epidemiology/virology
MH  - Sequence Analysis, RNA
MH  - Viral Fusion Proteins/*genetics/metabolism
MH  - Young Adult
EDAT- 2017/03/08 06:00
MHDA- 2017/03/16 06:00
CRDT- 2017/03/08 06:00
AID - 10.1099/jmm.0.000431 [doi]
PST - ppublish
SO  - J Med Microbiol. 2017 Feb;66(2):160-168. doi: 10.1099/jmm.0.000431.

<?xml version="1.0" encoding="UTF-8"?>
<b:Sources SelectedStyle="" xmlns:b="http://schemas.openxmlformats.org/officeDocument/2006/bibliography"  xmlns="http://schemas.openxmlformats.org/officeDocument/2006/bibliography" >
</b:Sources>