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Total cardiovascular risk for next 10 years among rural population of Nepal using WHO/ISH risk prediction chart.

Abstract Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality globally. Primary prevention of CVD based on total CVD risk approach using WHO/ISH risk prediction chart would be more effective to stratify population under different risk levels, prioritize and utilize the scarce resources of low and middle-income countries. This study estimated total 10-year CVD risk and determined the proportion of population who need immediate drug therapy among the rural population of Nepal.
PMID
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Authors

Mayor MeshTerms
Keywords

Cardiovascular diseases

Risk prediction

Rural population

Total 10-year CVD risk

WHO/ISH chart

Journal Title bmc research notes
Publication Year Start




PMID- 28270186
OWN - NLM
STAT- MEDLINE
DA  - 20170308
DCOM- 20170317
LR  - 20170317
IS  - 1756-0500 (Electronic)
IS  - 1756-0500 (Linking)
VI  - 10
IP  - 1
DP  - 2017 Mar 07
TI  - Total cardiovascular risk for next 10 years among rural population of Nepal using
      WHO/ISH risk prediction chart.
PG  - 120
LID - 10.1186/s13104-017-2436-9 [doi]
AB  - BACKGROUND: Cardiovascular diseases (CVD) are the leading cause of morbidity and 
      mortality globally. Primary prevention of CVD based on total CVD risk approach
      using WHO/ISH risk prediction chart would be more effective to stratify
      population under different risk levels, prioritize and utilize the scarce
      resources of low and middle-income countries. This study estimated total 10-year 
      CVD risk and determined the proportion of population who need immediate drug
      therapy among the rural population of Nepal. METHODS: A community based
      cross-sectional study conducted among 345 participants aged 40-80 years in rural 
      villages of Lamjung District of Nepal. They were selected randomly from total
      eighteen wards. Data were collected using WHO STEPS questionnaires. WHO/ISH risk 
      prediction chart for SEAR D was used to estimate total cardiovascular risk.
      Chi-square and independent t-test were used to test significance at the level of 
      p < 0.05 in SPSS version 16.0. RESULTS: Of the total participants, 55.4% were
      female. The mean age (standard deviation) of the participants was 53.5 +/- 10.1
      years. According to WHO/ISH chart proportions of low, moderate and high CVD risk 
      were 86.4%, 9.3%, and 4.3%, respectively. Eleven percent of participants were in 
      need of immediate pharmacotherapy. Age (p = 0.001), level of education (p = 0.01)
      and occupation (p = 0.001) were significantly associated with elevated CVD risk. 
      CONCLUSION: A large proportion of Nepalese rural population is at moderate and
      high CVD risk. Immediate pharmacological interventions are warranted for at least
      one in every ten individuals along with lifestyle interventions. Both
      population-wise and high-risk approaches are required to minimize CVD burden in
      the future.
FAU - Khanal, Mahesh Kumar
AU  - Khanal MK
AD  - Bangladesh Institute of Health Sciences (BIHS), Dhaka, Bangladesh.
      [email protected]
FAU - Ahmed, M S A Mansur
AU  - Ahmed MS
AD  - Department of Community Medicine, Bangladesh Institute of Health Sciences, Dhaka,
      Bangladesh.
FAU - Moniruzzaman, Mohammad
AU  - Moniruzzaman M
AD  - Department of Community Medicine, Bangladesh Institute of Health Sciences, Dhaka,
      Bangladesh.
FAU - Banik, Palash Chandra
AU  - Banik PC
AD  - Department of Community Medicine, Bangladesh Institute of Health Sciences, Dhaka,
      Bangladesh.
FAU - Dhungana, Raja Ram
AU  - Dhungana RR
AD  - Bangladesh Institute of Health Sciences (BIHS), Dhaka, Bangladesh.
FAU - Bhandari, Pratiksha
AU  - Bhandari P
AD  - Padmakanya Multiple Campus, Tribhuvan University (TU), Kathmandu, Nepal.
FAU - Devkota, Surya
AU  - Devkota S
AD  - Institute of Medicine (IOM), Tribhuvan University, Kathmandu, Nepal.
FAU - Shayami, Arun
AU  - Shayami A
AD  - Institute of Medicine (IOM), Tribhuvan University, Kathmandu, Nepal.
LA  - eng
PT  - Journal Article
DEP - 20170307
PL  - England
TA  - BMC Res Notes
JT  - BMC research notes
JID - 101462768
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Cardiovascular Diseases/*diagnosis/epidemiology/physiopathology/*prevention &
      control
MH  - Cross-Sectional Studies
MH  - Educational Status
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Nepal/epidemiology
MH  - Prevalence
MH  - Primary Prevention/*methods
MH  - Prognosis
MH  - Risk Assessment
MH  - Risk Factors
MH  - Rural Population
MH  - Social Class
MH  - Surveys and Questionnaires
MH  - World Health Organization
PMC - PMC5341399
OTO - NOTNLM
OT  - Cardiovascular diseases
OT  - Risk prediction
OT  - Rural population
OT  - Total 10-year CVD risk
OT  - WHO/ISH chart
EDAT- 2017/03/09 06:00
MHDA- 2017/03/18 06:00
CRDT- 2017/03/09 06:00
PHST- 2016/11/16 [received]
PHST- 2017/02/24 [accepted]
AID - 10.1186/s13104-017-2436-9 [doi]
AID - 10.1186/s13104-017-2436-9 [pii]
PST - epublish
SO  - BMC Res Notes. 2017 Mar 7;10(1):120. doi: 10.1186/s13104-017-2436-9.

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