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Development of a laser controlled device to modulate intraocular pressure.

Abstract The current standard of treatment for glaucoma is trabeculectomy. The use of glaucoma drainage devices has increased in recent years since its efficacy and safety was established as it provides an alternative surgical option. A downfall of these devices is the lack of proper flow rate control. Areas covered: In this paper we describe a glaucoma drainage device regulator that has already been protoyped and undergone initial testing. It consists of an implantable device with a semipermeable membrane that is used during glaucoma surgery and can be opened with either thermal or photodisruptive laser to adjust the amount of flow precisely and non-invasively, addressing the current difficulties of glaucoma surgeries. A literature search was conducted using MEDLINE and manuscript references for studies published in English between 2000 and 2015 using the terms glaucoma, trabeculectomy and glaucoma drainage devices. Expert commentary: The GDDR device can decrease surgical risk and allow surgeons to post-operatively adjust flow as clinically needed using a non-invasive method. Further testing is planned to substantiate these initial results and evaluate the device's biocompatibility, tunability and efficacy.
PMID
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Authors

Mayor MeshTerms

Intraocular Pressure

Keywords

Glaucoma

glaucoma drainage device regulator

glaucoma drainage devices

thermal or photodisruptive Laser

trabeculectomy

Journal Title expert review of medical devices
Publication Year Start




PMID- 28276751
OWN - NLM
STAT- MEDLINE
DA  - 20170309
DCOM- 20170317
LR  - 20170317
IS  - 1745-2422 (Electronic)
IS  - 1743-4440 (Linking)
VI  - 14
IP  - 3
DP  - 2017 Mar
TI  - Development of a laser controlled device to modulate intraocular pressure.
PG  - 229-236
LID - 10.1080/17434440.2017.1299571 [doi]
AB  - INTRODUCTION: The current standard of treatment for glaucoma is trabeculectomy.
      The use of glaucoma drainage devices has increased in recent years since its
      efficacy and safety was established as it provides an alternative surgical
      option. A downfall of these devices is the lack of proper flow rate control.
      Areas covered: In this paper we describe a glaucoma drainage device regulator
      that has already been protoyped and undergone initial testing. It consists of an 
      implantable device with a semipermeable membrane that is used during glaucoma
      surgery and can be opened with either thermal or photodisruptive laser to adjust 
      the amount of flow precisely and non-invasively, addressing the current
      difficulties of glaucoma surgeries. A literature search was conducted using
      MEDLINE and manuscript references for studies published in English between 2000
      and 2015 using the terms glaucoma, trabeculectomy and glaucoma drainage devices. 
      Expert commentary: The GDDR device can decrease surgical risk and allow surgeons 
      to post-operatively adjust flow as clinically needed using a non-invasive method.
      Further testing is planned to substantiate these initial results and evaluate the
      device's biocompatibility, tunability and efficacy.
FAU - Olson, Jeffrey L
AU  - Olson JL
AD  - a University of Colorado School of Medicine, Department of Ophthalmology , Rocky 
      Mountain Lions Eye Institute , Aurora , CO , USA.
AD  - b Galaxy Ophthalmics , Denver , CO , USA.
FAU - Bhandari, Ramanath
AU  - Bhandari R
AD  - a University of Colorado School of Medicine, Department of Ophthalmology , Rocky 
      Mountain Lions Eye Institute , Aurora , CO , USA.
AD  - b Galaxy Ophthalmics , Denver , CO , USA.
AD  - c Department of Ophthalmology , Springfield Clinic , Springfield , IL , USA.
FAU - Groman-Lupa, Sergio
AU  - Groman-Lupa S
AD  - a University of Colorado School of Medicine, Department of Ophthalmology , Rocky 
      Mountain Lions Eye Institute , Aurora , CO , USA.
FAU - Santos-Cantu, Daniela
AU  - Santos-Cantu D
AD  - a University of Colorado School of Medicine, Department of Ophthalmology , Rocky 
      Mountain Lions Eye Institute , Aurora , CO , USA.
FAU - Velez-Montoya, Raul
AU  - Velez-Montoya R
AD  - a University of Colorado School of Medicine, Department of Ophthalmology , Rocky 
      Mountain Lions Eye Institute , Aurora , CO , USA.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20170306
PL  - England
TA  - Expert Rev Med Devices
JT  - Expert review of medical devices
JID - 101230445
SB  - IM
MH  - Glaucoma/physiopathology/*surgery
MH  - Humans
MH  - *Intraocular Pressure
MH  - Laser Therapy/*instrumentation/*methods
MH  - Trabeculectomy/*instrumentation/*methods
OTO - NOTNLM
OT  - *Glaucoma
OT  - *glaucoma drainage device regulator
OT  - *glaucoma drainage devices
OT  - *thermal or photodisruptive Laser
OT  - *trabeculectomy
EDAT- 2017/03/10 06:00
MHDA- 2017/03/18 06:00
CRDT- 2017/03/10 06:00
AID - 10.1080/17434440.2017.1299571 [doi]
PST - ppublish
SO  - Expert Rev Med Devices. 2017 Mar;14(3):229-236. doi:
      10.1080/17434440.2017.1299571. Epub 2017 Mar 6.

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