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New solid state cadmium-zinc-telluride technology for cardiac single photon emission computed tomographic myocardial perfusion imaging.

Abstract Single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) is well established as diagnostic test for patients with suspected or known coronary artery disease. New camera systems have been developed with cadmium-zinc-telluride (CZT) detectors, novel collimator designs and reconstruction software. Areas covered: We review the current state of cardiac SPECT, advances in conventional camera technology and the development and clinical validation of solid-state CZT cameras. Expert commentary: The development of CZT systems is timely and addresses current issues for clinical SPECT imaging. These systems have a significant increase in photon sensitivity, permitting much lower radiation patient doses at a time when the lay and medical communities are very concerned about the radiation doses resulting from medical imaging. The increased count sensitivity permits shorter acquisition times and greater patient throughput which may address the ongoing and increasing issue of decreased funding for healthcare and, particularly, diagnostic imaging. The improved image resolution should improve diagnostic accuracy and increase the value of SPECT imaging for management of patients with CAD at a time of significant competition from other imaging modalities.
PMID
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Authors

Mayor MeshTerms

Software

Keywords

CAD

PET

SPECT

cadmium-zinc-telluride

radiation dose

Journal Title expert review of medical devices
Publication Year Start




PMID- 28276752
OWN - NLM
STAT- MEDLINE
DA  - 20170309
DCOM- 20170317
LR  - 20170317
IS  - 1745-2422 (Electronic)
IS  - 1743-4440 (Linking)
VI  - 14
IP  - 3
DP  - 2017 Mar
TI  - New solid state cadmium-zinc-telluride technology for cardiac single photon
      emission computed tomographic myocardial perfusion imaging.
PG  - 213-222
LID - 10.1080/17434440.2017.1296763 [doi]
AB  - INTRODUCTION: Single photon emission computed tomography (SPECT) myocardial
      perfusion imaging (MPI) is well established as diagnostic test for patients with 
      suspected or known coronary artery disease. New camera systems have been
      developed with cadmium-zinc-telluride (CZT) detectors, novel collimator designs
      and reconstruction software. Areas covered: We review the current state of
      cardiac SPECT, advances in conventional camera technology and the development and
      clinical validation of solid-state CZT cameras. Expert commentary: The
      development of CZT systems is timely and addresses current issues for clinical
      SPECT imaging. These systems have a significant increase in photon sensitivity,
      permitting much lower radiation patient doses at a time when the lay and medical 
      communities are very concerned about the radiation doses resulting from medical
      imaging. The increased count sensitivity permits shorter acquisition times and
      greater patient throughput which may address the ongoing and increasing issue of 
      decreased funding for healthcare and, particularly, diagnostic imaging. The
      improved image resolution should improve diagnostic accuracy and increase the
      value of SPECT imaging for management of patients with CAD at a time of
      significant competition from other imaging modalities.
FAU - Alenazy, Ali B
AU  - Alenazy AB
AD  - a Department of Medicine , University of Ottawa , Ottawa , Canada.
AD  - b Division of Cardiology , University of Ottawa Heart Institute , Ottawa ,
      Canada.
FAU - Wells, R Glenn
AU  - Wells RG
AD  - a Department of Medicine , University of Ottawa , Ottawa , Canada.
AD  - b Division of Cardiology , University of Ottawa Heart Institute , Ottawa ,
      Canada.
FAU - Ruddy, Terrence D
AU  - Ruddy TD
AD  - a Department of Medicine , University of Ottawa , Ottawa , Canada.
AD  - b Division of Cardiology , University of Ottawa Heart Institute , Ottawa ,
      Canada.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20170301
PL  - England
TA  - Expert Rev Med Devices
JT  - Expert review of medical devices
JID - 101230445
RN  - 00BH33GNGH (Cadmium)
RN  - J41CSQ7QDS (Zinc)
SB  - IM
MH  - Cadmium
MH  - Coronary Artery Disease/diagnosis/*diagnostic imaging
MH  - Humans
MH  - Myocardial Perfusion Imaging/*instrumentation
MH  - *Software
MH  - Tomography, Emission-Computed, Single-Photon/*instrumentation
MH  - Zinc
OTO - NOTNLM
OT  - *CAD
OT  - *PET
OT  - *SPECT
OT  - *cadmium-zinc-telluride
OT  - *radiation dose
EDAT- 2017/03/10 06:00
MHDA- 2017/03/10 06:00
CRDT- 2017/03/10 06:00
AID - 10.1080/17434440.2017.1296763 [doi]
PST - ppublish
SO  - Expert Rev Med Devices. 2017 Mar;14(3):213-222. doi:
      10.1080/17434440.2017.1296763. Epub 2017 Mar 1.

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