PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

Guillain-Barré Syndrome Presenting with Sinus Node Dysfunction and Refractory Shock.

Abstract BACKGROUND Guillain-Barré syndrome (GBS) is an acute inflammatory demyelinating polyneuropathy that is usually associated with preceding respiratory or gastrointestinal infection and has the hallmark manifestation of ascending flaccid paralysis. We report an atypical presentation of GBS. CASE REPORT A 76-year-old male presented with acute onset of diaphoresis and altered mental status. He subsequently developed severe bradycardia and refractory hypotension, which initially responded to dopamine infusion. A temporary pacemaker wire was placed to stabilize the heart rate but hypotension persisted. Acute autonomic dysfunction was suspected. Head and chest imaging was unrevealing. Lumbar puncture revealed albuminocytologic dissociation that was consistent with a diagnosis of GBS. Hospital course was complicated with acute kidney injury and metabolic acidosis. Plasmapharesis was initiated. The patient eventually died of multi-organ failure. CONCLUSIONS Autonomic dysfunction is a known but rare presentation of GBS. In patients presenting with refractory bradycardia and hypotension, GBS should be considered in the differential diagnosis.
PMID
Related Publications

Acute hemiplegia as a rare presentation of infantile Guillain-Barré syndrome.

Delayed recognition of Guillain-Barré syndrome in a child: a misleading respiratory distress.

Guillain-Barré Syndrome with asystole requiring permanent pacemaker: a case report.

Hypertensive encephalopathy as the initial manifestation of Guillain-Barré syndrome in a 7-year-old girl.

Guillain-Barré syndrome presenting with Raynaud's phenomenon: a case report.

Authors

Mayor MeshTerms
Keywords
Journal Title the american journal of case reports
Publication Year Start




PMID- 28283677
OWN - NLM
STAT- MEDLINE
DA  - 20170311
DCOM- 20170317
LR  - 20170317
IS  - 1941-5923 (Electronic)
IS  - 1941-5923 (Linking)
VI  - 18
DP  - 2017 Mar 11
TI  - Guillain-Barre Syndrome Presenting with Sinus Node Dysfunction and Refractory
      Shock.
PG  - 251-254
AB  - BACKGROUND Guillain-Barre syndrome (GBS) is an acute inflammatory demyelinating
      polyneuropathy that is usually associated with preceding respiratory or
      gastrointestinal infection and has the hallmark manifestation of ascending
      flaccid paralysis. We report an atypical presentation of GBS. CASE REPORT A
      76-year-old male presented with acute onset of diaphoresis and altered mental
      status. He subsequently developed severe bradycardia and refractory hypotension, 
      which initially responded to dopamine infusion. A temporary pacemaker wire was
      placed to stabilize the heart rate but hypotension persisted. Acute autonomic
      dysfunction was suspected. Head and chest imaging was unrevealing. Lumbar
      puncture revealed albuminocytologic dissociation that was consistent with a
      diagnosis of GBS. Hospital course was complicated with acute kidney injury and
      metabolic acidosis. Plasmapharesis was initiated. The patient eventually died of 
      multi-organ failure. CONCLUSIONS Autonomic dysfunction is a known but rare
      presentation of GBS. In patients presenting with refractory bradycardia and
      hypotension, GBS should be considered in the differential diagnosis.
FAU - Ha, Le Dung
AU  - Ha LD
AD  - Department of Internal Medicine, Rochester General Hospital, Rochester, NY, USA.
FAU - Abbas, Farrukh
AU  - Abbas F
AD  - Department of Internal Medicine, Rochester General Hospital, Rochester, NY, USA.
FAU - Rao, Mohan
AU  - Rao M
AD  - Sands-Constellation Heart Institute, Rochester General Hospital, Rochester, NY,
      USA.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20170311
PL  - United States
TA  - Am J Case Rep
JT  - The American journal of case reports
JID - 101489566
SB  - IM
MH  - Aged
MH  - Fatal Outcome
MH  - Guillain-Barre Syndrome/*complications/*diagnosis
MH  - Humans
MH  - Male
MH  - Multiple Organ Failure/*etiology
MH  - Sick Sinus Syndrome/*etiology
EDAT- 2017/03/12 06:00
MHDA- 2017/03/18 06:00
CRDT- 2017/03/12 06:00
AID - 902668 [pii]
PST - epublish
SO  - Am J Case Rep. 2017 Mar 11;18:251-254.

<?xml version="1.0" encoding="UTF-8"?>
<b:Sources SelectedStyle="" xmlns:b="http://schemas.openxmlformats.org/officeDocument/2006/bibliography"  xmlns="http://schemas.openxmlformats.org/officeDocument/2006/bibliography" >
</b:Sources>