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Milestone clinical trials of the National Surgical Adjuvant Breast and Bowel Project (NSABP).

Abstract The National Surgical Adjuvant Breast and Bowel Project (NSABP) has made significant contributions in reducing the extent of breast surgery and in improving outcomes of patients with early-stage breast cancer through the conduct of large randomized clinical trials evaluating local and systemic therapy. In 2014, the NSABP merged with two other US National Cancer Institute-funded cooperative groups, the Radiation Therapy Oncology Group (RTOG) and the Gynecologic Oncology Group (GOG), to form NRG Oncology. The combined organization has 218 member institutions with more than 600 affiliate centers located throughout the United States, Canada, Puerto Rico, and other international sites. Over the past half century, the NSABP has entered more than 150,000 women into clinical trials of breast cancer treatment and breast cancer prevention. Many of these trials have been instrumental in establishing new standards of care for patients with breast cancer.
PMID
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Authors

Mayor MeshTerms

Tissue Banks

Keywords

Breast cancer

clinical trials

locoregional therapy for breast cancer

systemic therapy for breast cancer

Journal Title chinese clinical oncology
Publication Year Start




PMID- 28285537
OWN - NLM
STAT- MEDLINE
DA  - 20170313
DCOM- 20170315
LR  - 20170315
IS  - 2304-3873 (Electronic)
IS  - 2304-3865 (Linking)
VI  - 6
IP  - 1
DP  - 2017 Feb
TI  - Milestone clinical trials of the National Surgical Adjuvant Breast and Bowel
      Project (NSABP).
PG  - 7
LID - 10.21037/cco.2017.02.02 [doi]
AB  - The National Surgical Adjuvant Breast and Bowel Project (NSABP) has made
      significant contributions in reducing the extent of breast surgery and in
      improving outcomes of patients with early-stage breast cancer through the conduct
      of large randomized clinical trials evaluating local and systemic therapy. In
      2014, the NSABP merged with two other US National Cancer Institute-funded
      cooperative groups, the Radiation Therapy Oncology Group (RTOG) and the
      Gynecologic Oncology Group (GOG), to form NRG Oncology. The combined organization
      has 218 member institutions with more than 600 affiliate centers located
      throughout the United States, Canada, Puerto Rico, and other international sites.
      Over the past half century, the NSABP has entered more than 150,000 women into
      clinical trials of breast cancer treatment and breast cancer prevention. Many of 
      these trials have been instrumental in establishing new standards of care for
      patients with breast cancer.
FAU - Rastogi, Priya
AU  - Rastogi P
AD  - National Surgical Adjuvant Breast and Bowel Project (NSABP), Pittsburgh, PA, USA;
      University of Pittsburgh Cancer Institute School of Medicine, Pittsburgh, PA,
      USA. priya.rastogi@nsabp.org.
FAU - Wickerham, D Lawrence
AU  - Wickerham DL
AD  - National Surgical Adjuvant Breast and Bowel Project (NSABP), Pittsburgh, PA, USA;
      Allegheny Health Network Cancer Institute, Pittsburgh, PA, USA.
FAU - Geyer, Charles E Jr
AU  - Geyer CE Jr
AD  - National Surgical Adjuvant Breast and Bowel Project (NSABP), Pittsburgh, PA, USA;
      Virginia Commonwealth University, Massey Cancer Center, Richmond, VA, USA.
FAU - Mamounas, Eleftherios P
AU  - Mamounas EP
AD  - National Surgical Adjuvant Breast and Bowel Project (NSABP), Pittsburgh, PA, USA;
      UF Health Cancer Center at Orland Health, Orlando, FL, USA.
FAU - Julian, Thomas B
AU  - Julian TB
AD  - National Surgical Adjuvant Breast and Bowel Project (NSABP), Pittsburgh, PA, USA;
      Allegheny Health Network Cancer Institute, Pittsburgh, PA, USA.
FAU - Wolmark, Norman
AU  - Wolmark N
AD  - National Surgical Adjuvant Breast and Bowel Project (NSABP), Pittsburgh, PA, USA;
      Allegheny Health Network Cancer Institute, Pittsburgh, PA, USA.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - China
TA  - Chin Clin Oncol
JT  - Chinese clinical oncology
JID - 101608375
SB  - IM
MH  - Antineoplastic Combined Chemotherapy Protocols/therapeutic use
MH  - Breast Neoplasms/*therapy
MH  - Carcinoma, Intraductal, Noninfiltrating/drug therapy
MH  - Chemotherapy, Adjuvant/methods
MH  - Clinical Trials as Topic
MH  - Female
MH  - Humans
MH  - Mastectomy
MH  - Neoadjuvant Therapy
MH  - Societies, Medical
MH  - *Tissue Banks
OTO - NOTNLM
OT  - *Breast cancer
OT  - *clinical trials
OT  - *locoregional therapy for breast cancer
OT  - *systemic therapy for breast cancer
EDAT- 2017/03/14 06:00
MHDA- 2017/03/16 06:00
CRDT- 2017/03/14 06:00
PHST- 2016/12/23 [received]
PHST- 2017/01/08 [accepted]
AID - 10.21037/cco.2017.02.02 [doi]
PST - ppublish
SO  - Chin Clin Oncol. 2017 Feb;6(1):7. doi: 10.21037/cco.2017.02.02.

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