PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

X-Linked Retinoschisis in Juveniles: Follow-Up by Optical Coherence Tomography.

Abstract Purpose. To explore the structural progression of X-linked retinoschisis (XLRS) in patients by using spectral-domain optical coherence tomography (SD-OCT). Design. Retrospective, observational study. Methods. Patients who were diagnosed with XLRS by genetic testing underwent comprehensive ophthalmological examinations from December 2014 to October 2016. Each eye was measured by SD-OCT using the same clinical protocol. A correlation between best-corrected visual acuity (VA) and SD-OCT measurements was observed. Results. Six patients demonstrated retinoschisis (12 eyes) and typical foveal cyst-like cavities (10 eyes) on SD-OCT images with a mean logMAR VA of 0.48. The median age was 7.5 years at the initial visit. Their foveal retinal thickness (516.9 μm) and choroid thickness (351.4 μm) decreased at a rate of 38.1 and 7.5 μm, respectively, at the 10.5-month follow-up visit; however, there were no significant differences (P = 0.622 and P = 0.406, resp.). There was no significant correlation between VA, the foveal retinal thickness, and subfoveal choroid thickness. Conclusions. SD-OCT images for XLRS patients during the juvenile period revealed no significant changes in the fundus structure, including the foveal retinal thickness and choroid thickness within one-year follow-up. There was a lack of correlation between VA, foveal retinal thickness, and subfoveal choroid thickness.
PMID
Related Publications

Wide-field spectral-domain optical coherence tomography in patients and carriers of X-linked retinoschisis.

Optical coherence tomography retinal thickness and volume measurements in X-linked retinoschisis.

Correlation between spectral-domain OCT findings and visual acuity in X-linked retinoschisis.

Clinical and genetic findings in Hungarian patients with X-linked juvenile retinoschisis.

Correlation of optical coherence tomography findings with visual acuity and macular lesions in patients with X-linked retinoschisis.

Authors

Mayor MeshTerms
Keywords
Journal Title biomed research international
Publication Year Start




PMID- 28286756
OWN - NLM
STAT- In-Process
DA  - 20170313
LR  - 20170313
IS  - 2314-6141 (Electronic)
VI  - 2017
DP  - 2017
TI  - X-Linked Retinoschisis in Juveniles: Follow-Up by Optical Coherence Tomography.
PG  - 1704623
LID - 10.1155/2017/1704623 [doi]
AB  - Purpose. To explore the structural progression of X-linked retinoschisis (XLRS)
      in patients by using spectral-domain optical coherence tomography (SD-OCT).
      Design. Retrospective, observational study. Methods. Patients who were diagnosed 
      with XLRS by genetic testing underwent comprehensive ophthalmological
      examinations from December 2014 to October 2016. Each eye was measured by SD-OCT 
      using the same clinical protocol. A correlation between best-corrected visual
      acuity (VA) and SD-OCT measurements was observed. Results. Six patients
      demonstrated retinoschisis (12 eyes) and typical foveal cyst-like cavities (10
      eyes) on SD-OCT images with a mean logMAR VA of 0.48. The median age was 7.5
      years at the initial visit. Their foveal retinal thickness (516.9 mum) and
      choroid thickness (351.4 mum) decreased at a rate of 38.1 and 7.5 mum,
      respectively, at the 10.5-month follow-up visit; however, there were no
      significant differences (P = 0.622 and P = 0.406, resp.). There was no
      significant correlation between VA, the foveal retinal thickness, and subfoveal
      choroid thickness. Conclusions. SD-OCT images for XLRS patients during the
      juvenile period revealed no significant changes in the fundus structure,
      including the foveal retinal thickness and choroid thickness within one-year
      follow-up. There was a lack of correlation between VA, foveal retinal thickness, 
      and subfoveal choroid thickness.
FAU - Hu, Qin-Rui
AU  - Hu QR
AD  - Department of Ophthalmology, Peking University People's Hospital, Key Laboratory 
      of Vision Loss and Restoration, Ministry of Education, Beijing Key Laboratory for
      the Diagnosis and Treatment of Retinal and Choroid Diseases, Beijing, China.
FAU - Huang, Lv-Zhen
AU  - Huang LZ
AD  - Department of Ophthalmology, Peking University People's Hospital, Key Laboratory 
      of Vision Loss and Restoration, Ministry of Education, Beijing Key Laboratory for
      the Diagnosis and Treatment of Retinal and Choroid Diseases, Beijing, China.
FAU - Chen, Xiao-Li
AU  - Chen XL
AUID- ORCID: 0000-0001-8020-5513
AD  - Department of Ophthalmology, Peking University People's Hospital, Key Laboratory 
      of Vision Loss and Restoration, Ministry of Education, Beijing Key Laboratory for
      the Diagnosis and Treatment of Retinal and Choroid Diseases, Beijing, China.
FAU - Xia, Hui-Ka
AU  - Xia HK
AD  - Department of Ophthalmology, Peking University People's Hospital, Key Laboratory 
      of Vision Loss and Restoration, Ministry of Education, Beijing Key Laboratory for
      the Diagnosis and Treatment of Retinal and Choroid Diseases, Beijing, China.
FAU - Li, Tian-Qi
AU  - Li TQ
AD  - Department of Ophthalmology, Peking University People's Hospital, Key Laboratory 
      of Vision Loss and Restoration, Ministry of Education, Beijing Key Laboratory for
      the Diagnosis and Treatment of Retinal and Choroid Diseases, Beijing, China.
FAU - Li, Xiao-Xin
AU  - Li XX
AUID- ORCID: 0000-0002-5161-9458
AD  - Department of Ophthalmology, Peking University People's Hospital, Key Laboratory 
      of Vision Loss and Restoration, Ministry of Education, Beijing Key Laboratory for
      the Diagnosis and Treatment of Retinal and Choroid Diseases, Beijing, China.
LA  - eng
PT  - Journal Article
DEP - 20170214
PL  - United States
TA  - Biomed Res Int
JT  - BioMed research international
JID - 101600173
PMC - PMC5329649
COI - The authors declare no competing financial interests.
EDAT- 2017/03/14 06:00
MHDA- 2017/03/14 06:00
CRDT- 2017/03/14 06:00
PHST- 2016/10/25 [received]
PHST- 2016/12/13 [revised]
PHST- 2017/01/23 [accepted]
AID - 10.1155/2017/1704623 [doi]
PST - ppublish
SO  - Biomed Res Int. 2017;2017:1704623. doi: 10.1155/2017/1704623. Epub 2017 Feb 14.

<?xml version="1.0" encoding="UTF-8"?>
<b:Sources SelectedStyle="" xmlns:b="http://schemas.openxmlformats.org/officeDocument/2006/bibliography"  xmlns="http://schemas.openxmlformats.org/officeDocument/2006/bibliography" >
</b:Sources>