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Effect of coronary dominance on 2-year outcomes after percutaneous coronary intervention in patients with acute coronary syndrome.

Abstract This retrospective, single-center, observational analysis from prospectively collected database evaluated whether left dominance affected the long-term outcomes of acute coronary syndrome patients undergoing percutaneous coronary intervention, and whether the effect was independent of SYNTAX score.
PMID
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Authors

Mayor MeshTerms

Percutaneous Coronary Intervention

Keywords

SYNTAX score

acute coronary syndrome

coronary anatomy

left dominance

Journal Title catheterization and cardiovascular interventions : official journal of the society for cardiac angiography & interventions
Publication Year Start




PMID- 28318135
OWN - NLM
STAT- MEDLINE
DA  - 20170320
DCOM- 20170327
LR  - 20170327
IS  - 1522-726X (Electronic)
IS  - 1522-1946 (Linking)
VI  - 89
IP  - S1
DP  - 2017 Mar
TI  - Effect of coronary dominance on 2-year outcomes after percutaneous coronary
      intervention in patients with acute coronary syndrome.
PG  - 549-554
LID - 10.1002/ccd.26978 [doi]
AB  - OBJECTIVES: This retrospective, single-center, observational analysis from
      prospectively collected database evaluated whether left dominance affected the
      long-term outcomes of acute coronary syndrome patients undergoing percutaneous
      coronary intervention, and whether the effect was independent of SYNTAX score.
      BACKGROUND: Left dominance is believed to be associated with worse prognoses. The
      anatomical SYNTAX score is a scoring system based on the complexity and severity 
      of coronary lesions and is thought to be a prognostic tool to predict short- and 
      long-term outcomes. There are few studies about whether the effect of left
      dominance is independent of SYNTAX score. METHODS: Between January 2013 and
      December 2013, 6255 consecutive acute coronary syndrome patients who were
      admitted to Fuwai hospital and underwent percutaneous coronary intervention (PCI)
      were enrolled in this study. Based on coronary dominance and the calculation
      methods of the SYNTAX score, patients were divided into a left-dominant group (LD
      group; 390 patients) and a right-dominant or co-dominant group (RD + Co group,
      5865 patients). RESULT: The 2-year mortality rate was significantly higher in the
      LD group than in the RD + Co group (2.58% vs. 1.23%, P = 0.024). In multivariate 
      Cox analysis, the independent predictors of mortality were coronary dominance,
      IABP support, age, baseline SYNTAX score, and ejection fraction. CONCLUSIONS: LD 
      was an independent predictor of long-term mortality in ACS patients undergoing
      PCI. The effect of LD still existed after adjustment for several important
      variables and was independent of SYNTAX score. (c) 2017 Wiley Periodicals, Inc.
CI  - (c) 2017 Wiley Periodicals, Inc.
FAU - He, Chen
AU  - He C
AD  - Department of Cardiology, State Key Laboratory of Cardiovascular Disease, Fuwai
      Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical
      Sciences and Peking Union Medical College, Beijing, 100037, China.
FAU - Ma, Yuan-Liang
AU  - Ma YL
AD  - Department of Cardiology, State Key Laboratory of Cardiovascular Disease, Fuwai
      Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical
      Sciences and Peking Union Medical College, Beijing, 100037, China.
FAU - Wang, Chuang-Shi
AU  - Wang CS
AD  - Department of Cardiology, State Key Laboratory of Cardiovascular Disease, Fuwai
      Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical
      Sciences and Peking Union Medical College, Beijing, 100037, China.
FAU - Song, Ying
AU  - Song Y
AD  - Department of Cardiology, State Key Laboratory of Cardiovascular Disease, Fuwai
      Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical
      Sciences and Peking Union Medical College, Beijing, 100037, China.
FAU - Tang, Xiao-Fang
AU  - Tang XF
AD  - Department of Cardiology, State Key Laboratory of Cardiovascular Disease, Fuwai
      Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical
      Sciences and Peking Union Medical College, Beijing, 100037, China.
FAU - Zhao, Xue-Yan
AU  - Zhao XY
AD  - Department of Cardiology, State Key Laboratory of Cardiovascular Disease, Fuwai
      Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical
      Sciences and Peking Union Medical College, Beijing, 100037, China.
FAU - Gao, Run-Lin
AU  - Gao RL
AD  - Department of Cardiology, State Key Laboratory of Cardiovascular Disease, Fuwai
      Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical
      Sciences and Peking Union Medical College, Beijing, 100037, China.
FAU - Yang, Yue-Jin
AU  - Yang YJ
AD  - Department of Cardiology, State Key Laboratory of Cardiovascular Disease, Fuwai
      Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical
      Sciences and Peking Union Medical College, Beijing, 100037, China.
FAU - Xu, Bo
AU  - Xu B
AD  - Department of Cardiology, State Key Laboratory of Cardiovascular Disease, Fuwai
      Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical
      Sciences and Peking Union Medical College, Beijing, 100037, China.
FAU - Yuan, Jin-Qing
AU  - Yuan JQ
AD  - Department of Cardiology, State Key Laboratory of Cardiovascular Disease, Fuwai
      Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical
      Sciences and Peking Union Medical College, Beijing, 100037, China.
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PT  - Observational Study
PL  - United States
TA  - Catheter Cardiovasc Interv
JT  - Catheterization and cardiovascular interventions : official journal of the
      Society for Cardiac Angiography & Interventions
JID - 100884139
SB  - IM
MH  - Acute Coronary Syndrome/complications/diagnostic imaging/mortality/*therapy
MH  - Aged
MH  - Chi-Square Distribution
MH  - China
MH  - Coronary Angiography
MH  - Coronary Vessel Anomalies/*complications/diagnostic imaging/mortality
MH  - Databases, Factual
MH  - Female
MH  - Humans
MH  - Kaplan-Meier Estimate
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - *Percutaneous Coronary Intervention/adverse effects/mortality
MH  - Predictive Value of Tests
MH  - Proportional Hazards Models
MH  - Retrospective Studies
MH  - Risk Assessment
MH  - Risk Factors
MH  - Time Factors
MH  - Treatment Outcome
OTO - NOTNLM
OT  - *SYNTAX score
OT  - *acute coronary syndrome
OT  - *coronary anatomy
OT  - *left dominance
EDAT- 2017/03/21 06:00
MHDA- 2017/03/28 06:00
CRDT- 2017/03/21 06:00
PHST- 2016/12/09 [received]
PHST- 2017/01/15 [revised]
PHST- 2017/01/17 [accepted]
AID - 10.1002/ccd.26978 [doi]
PST - ppublish
SO  - Catheter Cardiovasc Interv. 2017 Mar;89(S1):549-554. doi: 10.1002/ccd.26978.

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