PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

Intra-Abdominal Hypertension Causes Bacterial Growth in Lungs: An Animal Study.

Abstract To study the effect of intra-abdominal hypertension (IAH) on the frequency of pneumonia with an experimental study, thirteen Sprague-Dawley rats were included. Eight out of thirteen animals were randomly assigned to receive 10 ml of benzalkonium chloride 0.2% (megacolon group) and five animals received 10 ml NaCl 0.9% (controls). Animals were anaesthetized by intramuscular delivery of ketamine. The incidence of positivity for bacteria lung tissue cultures and mesenteric lymph node cultures was assessed at the 21st day after animals' sacrification, or before in case of death. All megacolon group animals presented progressive increase of the abdomen and increased IAP (≥10 mmHg) whereas the frequency of their evacuations was almost eliminated. Controls presented normal evacuations, no sign of abdominal distention, and normal IAP. In megacolon group animals, there was evidence of significant amount of bacteria in lung cultures. In contrast, no bacteria were found in control animals.
PMID
Related Publications

Intraabdominal hypertention--predisposing factor for visceral alterations and abdominal compartment syndrome.

Influence of two different levels of intra-abdominal hypertension on bacterial translocation in a porcine model.

Increase in intra-abdominal pressure raises brain venous pressure, leads to brain ischaemia and decreases brain magnesium content.

Matching positive end-expiratory pressure to intra-abdominal pressure improves oxygenation in a porcine sick lung model of intra-abdominal hypertension.

The effects of hemodynamic shock and increased intra-abdominal pressure on bacterial translocation.

Authors

Mayor MeshTerms
Keywords
Journal Title biomed research international
Publication Year Start




PMID- 28357400
OWN - NLM
STAT- MEDLINE
DA  - 20170330
DCOM- 20170418
LR  - 20170418
IS  - 2314-6141 (Electronic)
VI  - 2017
DP  - 2017
TI  - Intra-Abdominal Hypertension Causes Bacterial Growth in Lungs: An Animal Study.
PG  - 4601348
LID - 10.1155/2017/4601348 [doi]
AB  - To study the effect of intra-abdominal hypertension (IAH) on the frequency of
      pneumonia with an experimental study, thirteen Sprague-Dawley rats were included.
      Eight out of thirteen animals were randomly assigned to receive 10 ml of
      benzalkonium chloride 0.2% (megacolon group) and five animals received 10 ml NaCl
      0.9% (controls). Animals were anaesthetized by intramuscular delivery of
      ketamine. The incidence of positivity for bacteria lung tissue cultures and
      mesenteric lymph node cultures was assessed at the 21st day after animals'
      sacrification, or before in case of death. All megacolon group animals presented 
      progressive increase of the abdomen and increased IAP (>/=10 mmHg) whereas the
      frequency of their evacuations was almost eliminated. Controls presented normal
      evacuations, no sign of abdominal distention, and normal IAP. In megacolon group 
      animals, there was evidence of significant amount of bacteria in lung cultures.
      In contrast, no bacteria were found in control animals.
FAU - Papakrivou, Eleni
AU  - Papakrivou E
AD  - Department of Critical Care Medicine, University Hospital of Larissa, University 
      of Thessaly School of Medicine, Larisa, Greece; Department of Pediatric Surgery, 
      General Hospital of "G. Gennimatas", A' University Department, Aristotle
      University of Thessaloniki, Thessaloniki, Greece.
FAU - Makris, Demosthenes
AU  - Makris D
AUID- ORCID: 0000-0003-1951-6421
AD  - Department of Critical Care Medicine, University Hospital of Larissa, University 
      of Thessaly School of Medicine, Larisa, Greece.
FAU - Manoulakas, Efstratios
AU  - Manoulakas E
AD  - Department of Critical Care Medicine, University Hospital of Larissa, University 
      of Thessaly School of Medicine, Larisa, Greece.
FAU - Mitroudi, Magda
AU  - Mitroudi M
AD  - Department of Pediatric Surgery, General Hospital of "G. Gennimatas", A'
      University Department, Aristotle University of Thessaloniki, Thessaloniki,
      Greece.
FAU - Tepetes, Konstantinos
AU  - Tepetes K
AD  - Department of General Surgery, University Hospital of Larisa, University of
      Thessaly School of Medicine, Larisa, Greece.
FAU - Papazoglou, Konstantinos
AU  - Papazoglou K
AD  - Department of Pathologo-Anatomy, General Hospital of "G. Gennimatas",
      Thessaloniki, Greece.
FAU - Zakynthinos, Epaminondas
AU  - Zakynthinos E
AD  - Department of Critical Care Medicine, University Hospital of Larissa, University 
      of Thessaly School of Medicine, Larisa, Greece.
LA  - eng
PT  - Journal Article
DEP - 20170305
PL  - United States
TA  - Biomed Res Int
JT  - BioMed research international
JID - 101600173
RN  - 0 (Benzalkonium Compounds)
SB  - IM
MH  - Animals
MH  - Bacteria/classification/isolation & purification/*pathogenicity
MH  - Benzalkonium Compounds/toxicity
MH  - Disease Models, Animal
MH  - Humans
MH  - Intra-Abdominal Hypertension/chemically
      induced/complications/microbiology/*pathology
MH  - Lung/*microbiology/pathology
MH  - Lymph Nodes/microbiology/pathology
MH  - Pneumonia/chemically induced/etiology/*microbiology/pathology
MH  - Rats
PMC - PMC5357524
COI - The authors declare that they have no competing interests.
EDAT- 2017/03/31 06:00
MHDA- 2017/04/19 06:00
CRDT- 2017/03/31 06:00
PHST- 2016/09/16 [received]
PHST- 2016/12/25 [revised]
PHST- 2017/01/17 [accepted]
AID - 10.1155/2017/4601348 [doi]
PST - ppublish
SO  - Biomed Res Int. 2017;2017:4601348. doi: 10.1155/2017/4601348. Epub 2017 Mar 5.

<?xml version="1.0" encoding="UTF-8"?>
<b:Sources SelectedStyle="" xmlns:b="http://schemas.openxmlformats.org/officeDocument/2006/bibliography"  xmlns="http://schemas.openxmlformats.org/officeDocument/2006/bibliography" >
</b:Sources>