PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

Potential use of lactic acid bacteria Leuconostoc mesenteroides as a probiotic for the removal of Pb(II) toxicity.

Abstract It has been demonstrated that certain lactic acid bacteria (LAB) can sequester metal ions by binding them to their surfaces. In the present study, lead (Pb)-resistant LAB were isolated from kimchi, a Korean fermented food. A total of 96 different LAB strains were isolated, and 52 strains showed lead resistance. Among them, an LAB strain-96 (L-96) identified as Leuconostoc mesenteroides showed remarkable Pb resistance and removal capacity. The maximum adsorption capacity of this strain calculated using the Langmuir isotherm was 60.6 mg Pb/g. In an in vivo experiment, young male mice were provided with water (A), Pb-water (B), or Pb-water+ L-96 (C) during puberty. Lower glutamate oxaloacetate transaminase (GOT) and glutamate pyruvate transaminase (GPT) levels in Pb-exposed male mice that received strain L-96 as a probiotic were suggestive of reduced hepatotoxicity. Moreover, feces from mice treated with L-96 contained more Pb than feces from untreated mice. Increased Pb elimination likely reduced internal accumulation, and this hypothesis was supported by significantly lower Pb concentrations in kidneys and testes of the mice treated with strain L-96. The motility and ATP content of epididymal spermatozoa were partially restored if strain L-96 was administered. In conclusion, isolated L-96 LAB had lead-biosorption activity and efficiently detoxified lead-poisoned male mice, resulting in recovering male reproductive function. These results suggest the potential use of LAB as a probiotic to protect humans from the adverse effects of Pb exposure.
PMID
Related Publications

Isolation, characterisation and identification of lactic acid bacteria from bushera: a Ugandan traditional fermented beverage.

Effects of Leuconostoc mesenteroides starter cultures on microbial communities and metabolites during kimchi fermentation.

Immunomodulating activity of exopolysaccharide-producing Leuconostoc mesenteroides strain NTM048 from green peas.

In vitro and in vivo probiotic assessment of Leuconostoc mesenteroides P45 isolated from pulque, a Mexican traditional alcoholic beverage.

Isolation and identification of an exopolysaccharide-producing lactic acid bacterium strain from Chinese Paocai and biosorption of Pb(II) by its exopolysaccharide.

Authors

Mayor MeshTerms
Keywords

bioremediation

environmental health

exopolysaccharides

fermentation

lactic acid bacteria

Journal Title journal of microbiology (seoul, korea)
Publication Year Start




PMID- 28361342
OWN - NLM
STAT- In-Process
DA  - 20170331
LR  - 20170331
IS  - 1976-3794 (Electronic)
IS  - 1225-8873 (Linking)
VI  - 55
IP  - 4
DP  - 2017 Apr
TI  - Potential use of lactic acid bacteria Leuconostoc mesenteroides as a probiotic
      for the removal of Pb(II) toxicity.
PG  - 296-303
LID - 10.1007/s12275-017-6642-x [doi]
AB  - It has been demonstrated that certain lactic acid bacteria (LAB) can sequester
      metal ions by binding them to their surfaces. In the present study, lead
      (Pb)-resistant LAB were isolated from kimchi, a Korean fermented food. A total of
      96 different LAB strains were isolated, and 52 strains showed lead resistance.
      Among them, an LAB strain-96 (L-96) identified as Leuconostoc mesenteroides
      showed remarkable Pb resistance and removal capacity. The maximum adsorption
      capacity of this strain calculated using the Langmuir isotherm was 60.6 mg Pb/g. 
      In an in vivo experiment, young male mice were provided with water (A), Pb-water 
      (B), or Pb-water+ L-96 (C) during puberty. Lower glutamate oxaloacetate
      transaminase (GOT) and glutamate pyruvate transaminase (GPT) levels in Pb-exposed
      male mice that received strain L-96 as a probiotic were suggestive of reduced
      hepatotoxicity. Moreover, feces from mice treated with L-96 contained more Pb
      than feces from untreated mice. Increased Pb elimination likely reduced internal 
      accumulation, and this hypothesis was supported by significantly lower Pb
      concentrations in kidneys and testes of the mice treated with strain L-96. The
      motility and ATP content of epididymal spermatozoa were partially restored if
      strain L-96 was administered. In conclusion, isolated L-96 LAB had
      lead-biosorption activity and efficiently detoxified lead-poisoned male mice,
      resulting in recovering male reproductive function. These results suggest the
      potential use of LAB as a probiotic to protect humans from the adverse effects of
      Pb exposure.
FAU - Yi, Young-Joo
AU  - Yi YJ
AD  - Division of Biotechnology, Chonbuk National University, Iksan, 54596, Republic of
      Korea.
AD  - Safety, Environment and Life Science Institute, Chonbuk National University,
      Iksan, 54596, Republic of Korea.
FAU - Lim, Jeong-Muk
AU  - Lim JM
AD  - Division of Biotechnology, Chonbuk National University, Iksan, 54596, Republic of
      Korea.
AD  - Advanced Institute of Environment and Bioscience, College of Environmental and
      Bioresource Sciences, Chonbuk National University, Iksan, 54596, Republic of
      Korea.
FAU - Gu, Suna
AU  - Gu S
AD  - Division of Biotechnology, Chonbuk National University, Iksan, 54596, Republic of
      Korea.
FAU - Lee, Wan-Kyu
AU  - Lee WK
AD  - College of Veterinary Medicine, Chungbuk National University, Cheongju, 28644,
      Republic of Korea.
FAU - Oh, Eunyoung
AU  - Oh E
AD  - Division of Biotechnology, Chonbuk National University, Iksan, 54596, Republic of
      Korea.
FAU - Lee, Sang-Myeong
AU  - Lee SM
AD  - Division of Biotechnology, Chonbuk National University, Iksan, 54596, Republic of
      Korea. [email protected]
AD  - Safety, Environment and Life Science Institute, Chonbuk National University,
      Iksan, 54596, Republic of Korea. [email protected]
FAU - Oh, Byung-Taek
AU  - Oh BT
AD  - Division of Biotechnology, Chonbuk National University, Iksan, 54596, Republic of
      Korea. [email protected]
AD  - Advanced Institute of Environment and Bioscience, College of Environmental and
      Bioresource Sciences, Chonbuk National University, Iksan, 54596, Republic of
      Korea. [email protected]
LA  - eng
PT  - Journal Article
DEP - 20170331
PL  - Korea (South)
TA  - J Microbiol
JT  - Journal of microbiology (Seoul, Korea)
JID - 9703165
OTO - NOTNLM
OT  - bioremediation
OT  - environmental health
OT  - exopolysaccharides
OT  - fermentation
OT  - lactic acid bacteria
EDAT- 2017/04/01 06:00
MHDA- 2017/04/01 06:00
CRDT- 2017/04/01 06:00
PHST- 2016/12/16 [received]
PHST- 2017/02/09 [accepted]
PHST- 2017/02/09 [revised]
AID - 10.1007/s12275-017-6642-x [doi]
AID - 10.1007/s12275-017-6642-x [pii]
PST - ppublish
SO  - J Microbiol. 2017 Apr;55(4):296-303. doi: 10.1007/s12275-017-6642-x. Epub 2017
      Mar 31.

<?xml version="1.0" encoding="UTF-8"?>
<b:Sources SelectedStyle="" xmlns:b="http://schemas.openxmlformats.org/officeDocument/2006/bibliography"  xmlns="http://schemas.openxmlformats.org/officeDocument/2006/bibliography" >
</b:Sources>