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Systemic therapies and cognitive impairment for breast cancer: an overview of the current literature.

Abstract Both endocrine and chemotherapy can be utilized for breast cancer patients' management, in multiple setting (i.e., primary systemic therapy, adjuvant, metastatic treatment). Health-related quality of life in breast cancer survivors can be significantly influenced by cognitive impairment, which has been related in several previously reported experiences to systemic therapies administration. However, although the growing body of literature, the impact of both chemo- and endocrine therapy on cognitive function is currently unclear, due to many confounding factors (i.e., multiple therapies, duration of therapy, comorbidity, age). The aim of the present review is to present an overview of the current literature concerning the possible influence of endocrine and systemic therapy on breast cancer patients' cognitive impairment.
PMID
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Authors

Mayor MeshTerms
Keywords

Breast cancer

Cognitive impairment

Endocrine therapy

Quality of life

Systemic therapy

Journal Title medical oncology (northwood, london, england)
Publication Year Start




PMID- 28364269
OWN - NLM
STAT- MEDLINE
DA  - 20170401
DCOM- 20170419
LR  - 20170419
IS  - 1559-131X (Electronic)
IS  - 1357-0560 (Linking)
VI  - 34
IP  - 5
DP  - 2017 May
TI  - Systemic therapies and cognitive impairment for breast cancer: an overview of the
      current literature.
PG  - 74
LID - 10.1007/s12032-017-0935-0 [doi]
AB  - Both endocrine and chemotherapy can be utilized for breast cancer patients'
      management, in multiple setting (i.e., primary systemic therapy, adjuvant,
      metastatic treatment). Health-related quality of life in breast cancer survivors 
      can be significantly influenced by cognitive impairment, which has been related
      in several previously reported experiences to systemic therapies administration. 
      However, although the growing body of literature, the impact of both chemo- and
      endocrine therapy on cognitive function is currently unclear, due to many
      confounding factors (i.e., multiple therapies, duration of therapy, comorbidity, 
      age). The aim of the present review is to present an overview of the current
      literature concerning the possible influence of endocrine and systemic therapy on
      breast cancer patients' cognitive impairment.
FAU - Meattini, Icro
AU  - Meattini I
AUID- ORCID: http://orcid.org/0000-0002-1861-2895
AD  - Azienda Ospedaliero Universitaria Careggi - University of Florence, Largo G.A.
      Brambilla 3, 50134, Florence, Italy. [email protected]
FAU - Desideri, Isacco
AU  - Desideri I
AD  - Azienda Ospedaliero Universitaria Careggi - University of Florence, Largo G.A.
      Brambilla 3, 50134, Florence, Italy.
FAU - Francolini, Giulio
AU  - Francolini G
AD  - Azienda Ospedaliero Universitaria Careggi - University of Florence, Largo G.A.
      Brambilla 3, 50134, Florence, Italy.
FAU - Vannini, Agnese
AU  - Vannini A
AD  - Azienda Ospedaliero Universitaria Careggi - University of Florence, Largo G.A.
      Brambilla 3, 50134, Florence, Italy.
FAU - Perna, Marco
AU  - Perna M
AD  - Azienda Ospedaliero Universitaria Careggi - University of Florence, Largo G.A.
      Brambilla 3, 50134, Florence, Italy.
FAU - Garlatti, Pietro
AU  - Garlatti P
AD  - Azienda Ospedaliero Universitaria Careggi - University of Florence, Largo G.A.
      Brambilla 3, 50134, Florence, Italy.
FAU - Grassi, Roberta
AU  - Grassi R
AD  - Azienda Ospedaliero Universitaria Careggi - University of Florence, Largo G.A.
      Brambilla 3, 50134, Florence, Italy.
FAU - Livi, Lorenzo
AU  - Livi L
AD  - Azienda Ospedaliero Universitaria Careggi - University of Florence, Largo G.A.
      Brambilla 3, 50134, Florence, Italy.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20170331
PL  - United States
TA  - Med Oncol
JT  - Medical oncology (Northwood, London, England)
JID - 9435512
SB  - IM
MH  - Breast Neoplasms/*psychology/*therapy
MH  - Cognition Disorders/*etiology
MH  - Female
MH  - Humans
OTO - NOTNLM
OT  - Breast cancer
OT  - Cognitive impairment
OT  - Endocrine therapy
OT  - Quality of life
OT  - Systemic therapy
EDAT- 2017/04/02 06:00
MHDA- 2017/04/20 06:00
CRDT- 2017/04/02 06:00
PHST- 2017/03/02 [received]
PHST- 2017/03/28 [accepted]
AID - 10.1007/s12032-017-0935-0 [doi]
AID - 10.1007/s12032-017-0935-0 [pii]
PST - ppublish
SO  - Med Oncol. 2017 May;34(5):74. doi: 10.1007/s12032-017-0935-0. Epub 2017 Mar 31.

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