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Anterior segment migration of dexamethasone implant: risk factors, complications, and management.

Abstract To describe the risk factors, clinical course, and complications related to anterior segment migration of a dexamethasone (DEX) intravitreal implant, and review over potential management strategies.
PMID
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Dexamethasone implant anterior chamber migration: risk factors, complications, and management strategies.

Authors

Mayor MeshTerms
Keywords
Journal Title current opinion in ophthalmology
Publication Year Start




PMID- 28376511
OWN - NLM
STAT- MEDLINE
DA  - 20170404
DCOM- 20170418
LR  - 20170418
IS  - 1531-7021 (Electronic)
IS  - 1040-8738 (Linking)
VI  - 28
IP  - 3
DP  - 2017 May
TI  - Anterior segment migration of dexamethasone implant: risk factors, complications,
      and management.
PG  - 246-251
LID - 10.1097/ICU.0000000000000365 [doi]
AB  - PURPOSE OF REVIEW: To describe the risk factors, clinical course, and
      complications related to anterior segment migration of a dexamethasone (DEX)
      intravitreal implant, and review over potential management strategies. RECENT
      FINDINGS: Recent reports have demonstrated that migration of a DEX implant into
      the anterior chamber may occur in patients with higher risk ocular
      characteristics. Although a relatively rare occurrence, DEX implant migration
      carries the possibility of inducing potentially vision-threatening corneal
      endothelial decompensation and edema. SUMMARY: Any combination of previous pars
      plana vitrectomy, an open/defective lens capsule, and/or iris defects may
      increase the risk of DEX implant migration into the anterior chamber. In the
      setting of a DEX implant that has moved into the anterior segment with corneal
      edema already present, urgent removal of the implant is warranted to reduce the
      risk of permanent visual compromise.
FAU - Rahimy, Ehsan
AU  - Rahimy E
AD  - aDepartment of Ophthalmology, Palo Alto Medical Foundation, Palo AltobNorthern
      California Retina Vitreous Associates, Mountain ViewcDepartment of Ophthalmology,
      University of California, San Francisco, California, USA.
FAU - Khurana, Rahul N
AU  - Khurana RN
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Curr Opin Ophthalmol
JT  - Current opinion in ophthalmology
JID - 9011108
RN  - 0 (Drug Implants)
RN  - 0 (Glucocorticoids)
RN  - 7S5I7G3JQL (Dexamethasone)
SB  - IM
MH  - Anterior Eye Segment/*pathology
MH  - Device Removal
MH  - Dexamethasone/*administration & dosage
MH  - Drug Implants/*adverse effects
MH  - Foreign-Body Migration/*etiology/surgery
MH  - Glucocorticoids/*administration & dosage
MH  - Humans
MH  - Risk Factors
MH  - Vitrectomy
EDAT- 2017/04/05 06:00
MHDA- 2017/04/19 06:00
CRDT- 2017/04/05 06:00
AID - 10.1097/ICU.0000000000000365 [doi]
AID - 00055735-201705000-00008 [pii]
PST - ppublish
SO  - Curr Opin Ophthalmol. 2017 May;28(3):246-251. doi: 10.1097/ICU.0000000000000365.

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