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PMID- 28384147
STAT- In-Process
DA  - 20170406
LR  - 20170406
IS  - 1175-8716 (Electronic)
IS  - 0028-8446 (Linking)
VI  - 130
IP  - 1453
DP  - 2017 Apr 07
TI  - Trends in New Zealand stroke thrombolysis treatment rates.
PG  - 50-56
AB  - AIMS: To describe trends in treatment delays and short-term outcome over the
      first 18 months of the New Zealand stroke thrombolysis register. METHODS: The
      National Stroke Network introduced a central register of all ischaemic stroke
      patients treated with intravenous alteplase on January 1, 2015. The aim was to
      increase thrombolysis treatment rates and drive improvements in safety. RESULTS: 
      From January 1, 2015 to June 30, 2016, alteplase was given to 623 patients [344
      men, mean (range) age 70 (22-98) years] out of a total of 8,857 ischaemic and
      unspecified stroke patients, giving a thrombolysis rate of 7.0%. Between the
      first and second halves of the audit, there were more patients thrombolysed [350 
      of 4,456 (7.9%) versus 273 of 4,401 (6.8%); p=0.001] and more treated within 60
      minutes of hospital arrival [137 of 325 (42%) versus 71 of 250 (28%), p=0.001].
      Door-to-needle time reduced from 77 minutes to 64 minutes (p=0.002) and the
      onset-to-treatment reduced from 162 minutes to 140 minutes (p=0.070). Rates of
      symptomatic intracranial haemorrhage (4.3% patients) and survival at day seven
      (93%) were stable. CONCLUSIONS: There have been improvements in stroke
      thrombolysis rates and treatment delays in New Zealand hospitals since the
      institution of the National Stroke Network thrombolysis register. The Network
      will continue to adjust key performance indicators, and stroke thrombolysis
      targets for individual DHBs have been increased to 8% for 2017 and 10% for 2018.
FAU - Liu, Qiliang
AU  - Liu Q
AD  - Trainee Intern, Department of Neurology, Auckland City Hospital and University of
FAU - Ranta, Annemarei Anna
AU  - Ranta AA
AD  - Neurologist and National Clinical Leader Stroke, Department of Neurology,
      Wellington Regional Hospital and University of Otago.
FAU - Abernethy, Ginny
AU  - Abernethy G
AD  - National Stroke Network Coordinator, Stroke Foundation of New Zealand.
FAU - Barber, P Alan
AU  - Barber PA
AD  - Professor, Neurologist and Director of the Auckland Hospital Stroke Service,
      Department of Neurology, Auckland City Hospital and University of Auckland,
LA  - eng
PT  - Journal Article
DEP - 20170407
PL  - New Zealand
TA  - N Z Med J
JT  - The New Zealand medical journal
JID - 0401067
COI - Nil.
EDAT- 2017/04/07 06:00
MHDA- 2017/04/07 06:00
CRDT- 2017/04/07 06:00
PST - epublish
SO  - N Z Med J. 2017 Apr 7;130(1453):50-56.

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