Trends in New Zealand stroke thrombolysis treatment rates.
|Abstract||To describe trends in treatment delays and short-term outcome over the first 18 months of the New Zealand stroke thrombolysis register.|
Thrombolysis for acute ischaemic stroke with alteplase in an Asian population: results of the multicenter, multinational Safe Implementation of Thrombolysis in Stroke-Non-European Union World (SITS-NEW).
Effect of treatment delay, age, and stroke severity on the effects of intravenous thrombolysis with alteplase for acute ischaemic stroke: a meta-analysis of individual patient data from randomised trials.
|Journal Title||the new zealand medical journal|
|Publication Year Start||2017-01-01|
PMID- 28384147 OWN - NLM STAT- In-Process DA - 20170406 LR - 20170406 IS - 1175-8716 (Electronic) IS - 0028-8446 (Linking) VI - 130 IP - 1453 DP - 2017 Apr 07 TI - Trends in New Zealand stroke thrombolysis treatment rates. PG - 50-56 AB - AIMS: To describe trends in treatment delays and short-term outcome over the first 18 months of the New Zealand stroke thrombolysis register. METHODS: The National Stroke Network introduced a central register of all ischaemic stroke patients treated with intravenous alteplase on January 1, 2015. The aim was to increase thrombolysis treatment rates and drive improvements in safety. RESULTS: From January 1, 2015 to June 30, 2016, alteplase was given to 623 patients [344 men, mean (range) age 70 (22-98) years] out of a total of 8,857 ischaemic and unspecified stroke patients, giving a thrombolysis rate of 7.0%. Between the first and second halves of the audit, there were more patients thrombolysed [350 of 4,456 (7.9%) versus 273 of 4,401 (6.8%); p=0.001] and more treated within 60 minutes of hospital arrival [137 of 325 (42%) versus 71 of 250 (28%), p=0.001]. Door-to-needle time reduced from 77 minutes to 64 minutes (p=0.002) and the onset-to-treatment reduced from 162 minutes to 140 minutes (p=0.070). Rates of symptomatic intracranial haemorrhage (4.3% patients) and survival at day seven (93%) were stable. CONCLUSIONS: There have been improvements in stroke thrombolysis rates and treatment delays in New Zealand hospitals since the institution of the National Stroke Network thrombolysis register. The Network will continue to adjust key performance indicators, and stroke thrombolysis targets for individual DHBs have been increased to 8% for 2017 and 10% for 2018. FAU - Liu, Qiliang AU - Liu Q AD - Trainee Intern, Department of Neurology, Auckland City Hospital and University of Auckland. FAU - Ranta, Annemarei Anna AU - Ranta AA AD - Neurologist and National Clinical Leader Stroke, Department of Neurology, Wellington Regional Hospital and University of Otago. FAU - Abernethy, Ginny AU - Abernethy G AD - National Stroke Network Coordinator, Stroke Foundation of New Zealand. FAU - Barber, P Alan AU - Barber PA AD - Professor, Neurologist and Director of the Auckland Hospital Stroke Service, Department of Neurology, Auckland City Hospital and University of Auckland, Auckland. LA - eng PT - Journal Article DEP - 20170407 PL - New Zealand TA - N Z Med J JT - The New Zealand medical journal JID - 0401067 COI - Nil. EDAT- 2017/04/07 06:00 MHDA- 2017/04/07 06:00 CRDT- 2017/04/07 06:00 PST - epublish SO - N Z Med J. 2017 Apr 7;130(1453):50-56.
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