PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.




PMID- 28395057
OWN - NLM
STAT- MEDLINE
DA  - 20170410
DCOM- 20170414
LR  - 20170414
IS  - 1943-7722 (Electronic)
IS  - 0002-9173 (Linking)
VI  - 147
IP  - 3
DP  - 2017 Mar 01
TI  - Early miR-223 Upregulation in Gastroesophageal Carcinogenesis.
PG  - 301-308
LID - 10.1093/ajcp/aqx004 [doi]
AB  - Objectives: To test miR-223 upregulation during gastric (intestinal-type) and
      Barrett esophageal carcinogenesis. Methods: miR-223 expression was assessed by
      quantitative reverse transcription polymerase chain reaction in a series of 280
      gastroesophageal biopsy samples representative of the whole spectrum of
      phenotypic changes involved in both carcinogenetic cascades. The results were
      further validated by in situ hybridization on multiple tissue specimens obtained 
      from six surgically treated gastroesophageal adenocarcinomas. miR-223 expression 
      was also assessed in plasma samples from 30 patients with early stage (ie, stages
      I and II) gastroesophageal adenocarcinoma and relative controls. Results: In both
      gastric and esophageal models, miR-223 expression significantly increased along
      with the severity of the considered lesions (analysis of variance, P < .001).
      Among atrophic gastritis and long-segment Barrett esophagus samples, miR-223
      overexpression was significantly associated with the score of intestinal
      metaplasia. miR-223 plasma levels were significantly upregulated in patients with
      cancer compared with controls ( t test, both P < .001). Conclusions: miR-223
      early upregulation observed in tissue samples and its diagnostic value in
      discriminating patients with early adenocarcinoma by plasma testing provide a
      solid rationale for further exploring the diagnostic reliability of this microRNA
      as a novel biomarker in gastroesophageal adenocarcinoma secondary prevention
      strategies.
FAU - Fassan, Matteo
AU  - Fassan M
AD  - From the Department of Medicine (DIMED), Surgical Pathology and Cytopathology
      Unit.
FAU - Saraggi, Deborah
AU  - Saraggi D
AD  - From the Department of Medicine (DIMED), Surgical Pathology and Cytopathology
      Unit.
FAU - Balsamo, Laura
AU  - Balsamo L
AD  - From the Department of Medicine (DIMED), Surgical Pathology and Cytopathology
      Unit.
FAU - Realdon, Stefano
AU  - Realdon S
AD  - Gastroenterology Unit.
FAU - Scarpa, Marco
AU  - Scarpa M
AD  - Surgery Unit, Istituto Oncologico Veneto, IOV-IRCCS, Padua, Italy.
FAU - Castoro, Carlo
AU  - Castoro C
AD  - Surgery Unit, Istituto Oncologico Veneto, IOV-IRCCS, Padua, Italy.
FAU - Coati, Irene
AU  - Coati I
AD  - From the Department of Medicine (DIMED), Surgical Pathology and Cytopathology
      Unit.
FAU - Salmaso, Roberta
AU  - Salmaso R
AD  - From the Department of Medicine (DIMED), Surgical Pathology and Cytopathology
      Unit.
FAU - Farinati, Fabio
AU  - Farinati F
AD  - Department of Surgical Oncology and Gastroenterology (DiSCOG), Gastroenterology
      Unit.
FAU - Guzzardo, Vincenza
AU  - Guzzardo V
AD  - From the Department of Medicine (DIMED), Surgical Pathology and Cytopathology
      Unit.
FAU - Arcidiacono, Diletta
AU  - Arcidiacono D
AD  - Department of Surgical Oncology and Gastroenterology (DiSCOG), Gastroenterology
      Unit.
AD  - Venetian Institute of Molecular Medicine.
FAU - Munari, Giada
AU  - Munari G
AD  - From the Department of Medicine (DIMED), Surgical Pathology and Cytopathology
      Unit.
FAU - Gasparini, Pierluigi
AU  - Gasparini P
AD  - Comprehensive Cancer Center, Department of Molecular Virology, Immunology and
      Medical Genetics, The Ohio State University, Columbus.
FAU - Veronese, Nicola
AU  - Veronese N
AD  - Department of Medicine (DIMED), Geriatrics Division, University of Padua, Padua, 
      Italy.
FAU - Luchini, Claudio
AU  - Luchini C
AD  - Surgical Pathology Unit, Santa Chiara Hospital, Trento, Italy.
FAU - Valeri, Nicola
AU  - Valeri N
AD  - Gastrointestinal Oncology and Lymphoma, Royal Mardsen Hospital, London and
      Sutton, UK.
AD  - Department of Molecular Pathology, Institute of Cancer Research, London and
      Sutton, UK.
FAU - Rugge, Massimo
AU  - Rugge M
AD  - From the Department of Medicine (DIMED), Surgical Pathology and Cytopathology
      Unit.
AD  - Veneto Tumour Registry, Padua, Italy.
LA  - eng
PT  - Journal Article
PL  - England
TA  - Am J Clin Pathol
JT  - American journal of clinical pathology
JID - 0370470
RN  - 0 (Biomarkers, Tumor)
RN  - 0 (MIRN223 microRNA, human)
RN  - 0 (MicroRNAs)
SB  - AIM
SB  - IM
MH  - Adenocarcinoma/diagnosis/genetics/pathology
MH  - Aged
MH  - Barrett Esophagus/genetics/pathology
MH  - Biomarkers, Tumor/*analysis
MH  - Carcinogenesis/genetics/pathology
MH  - Early Detection of Cancer/*methods
MH  - Esophageal Neoplasms/diagnosis/genetics/*pathology
MH  - Esophagogastric Junction/pathology
MH  - Female
MH  - Humans
MH  - In Situ Hybridization
MH  - Male
MH  - MicroRNAs/analysis/*biosynthesis
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Reverse Transcriptase Polymerase Chain Reaction
MH  - Stomach Neoplasms/diagnosis/genetics/*pathology
MH  - Up-Regulation
OTO - NOTNLM
OT  - Barrett carcinogenesis
OT  - Gastric adenocarcinoma
OT  - Preneoplastic lesions
OT  - microRNA
EDAT- 2017/04/11 06:00
MHDA- 2017/04/15 06:00
CRDT- 2017/04/11 06:00
AID - 3053472 [pii]
AID - 10.1093/ajcp/aqx004 [doi]
PST - ppublish
SO  - Am J Clin Pathol. 2017 Mar 1;147(3):301-308. doi: 10.1093/ajcp/aqx004.

<?xml version="1.0" encoding="UTF-8"?>
<b:Sources SelectedStyle="" xmlns:b="http://schemas.openxmlformats.org/officeDocument/2006/bibliography"  xmlns="http://schemas.openxmlformats.org/officeDocument/2006/bibliography" >
</b:Sources>