PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

Multiorgan Involvement Confounding the Diagnosis of Bartonella henselae Infective Endocarditis in Children With Congenital Heart Disease.

Abstract Two children with congenital heart disease status post surgical correction presented with prolonged constitutional symptoms, hepatosplenomegaly and pancytopenia. Concern for malignancy prompted bone marrow biopsies that were without evidence thereof. In case 1, echocardiography identified a multilobulated vegetation on the conduit valve. In case 2, transthoracic, transesophageal and intracardiac echocardiography were performed and were without evidence of cardiac vegetations; however, pulmonic emboli raised concern for infective endocarditis. Both patients underwent surgical resection of the infected material and had histopathologic evidence of infective endocarditis. Further diagnostics identified elevated cytoplasmic antineutrophil cytoplasmic antibodies and antiproteinase 3 antibodies in addition to acute kidney injury with crescentic glomerulonephritis on renal biopsy. Serologic evidence of infection with Bartonella henselae was observed in both patients. These 2 cases highlight the potential multiorgan involvement that may confound the diagnosis of culture-negative infective endocarditis caused by B. henselae.
PMID
Related Publications

Culture negative endocarditis caused by Bartonella henselae in a child with congenital heart disease.

Culture of Bartonella quintana and Bartonella henselae from human samples: a 5-year experience (1993 to 1998).

Bartonella henselae Infective Endocarditis Detected by a Prolonged Blood Culture.

Culture-negative endocarditis caused by Bartonella henselae.

Multi-Organ Involvement Confounding the Diagnosis of Bartonella henselae Infective Endocarditis in Children with Congenital Heart Disease.

Authors

Mayor MeshTerms
Keywords
Journal Title the pediatric infectious disease journal
Publication Year Start




PMID- 28403058
OWN - NLM
STAT- MEDLINE
DA  - 20170413
DCOM- 20170420
LR  - 20170420
IS  - 1532-0987 (Electronic)
IS  - 0891-3668 (Linking)
VI  - 36
IP  - 5
DP  - 2017 May
TI  - Multiorgan Involvement Confounding the Diagnosis of Bartonella henselae Infective
      Endocarditis in Children With Congenital Heart Disease.
PG  - 516-520
LID - 10.1097/INF.0000000000001510 [doi]
AB  - Two children with congenital heart disease status post surgical correction
      presented with prolonged constitutional symptoms, hepatosplenomegaly and
      pancytopenia. Concern for malignancy prompted bone marrow biopsies that were
      without evidence thereof. In case 1, echocardiography identified a multilobulated
      vegetation on the conduit valve. In case 2, transthoracic, transesophageal and
      intracardiac echocardiography were performed and were without evidence of cardiac
      vegetations; however, pulmonic emboli raised concern for infective endocarditis. 
      Both patients underwent surgical resection of the infected material and had
      histopathologic evidence of infective endocarditis. Further diagnostics
      identified elevated cytoplasmic antineutrophil cytoplasmic antibodies and
      antiproteinase 3 antibodies in addition to acute kidney injury with crescentic
      glomerulonephritis on renal biopsy. Serologic evidence of infection with
      Bartonella henselae was observed in both patients. These 2 cases highlight the
      potential multiorgan involvement that may confound the diagnosis of
      culture-negative infective endocarditis caused by B. henselae.
FAU - Ouellette, Christopher P
AU  - Ouellette CP
AD  - From the *Division of Infectious Diseases and Immunology, Department of
      Pediatrics, daggerDivision of Hematology and Oncology, Department of Pediatrics, 
      and double daggerDivision of Cardiology, Department of Pediatrics, Nationwide
      Children's Hospital, The Ohio State University, Columbus, Ohio.
FAU - Joshi, Sarita
AU  - Joshi S
FAU - Texter, Karen
AU  - Texter K
FAU - Jaggi, Preeti
AU  - Jaggi P
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Pediatr Infect Dis J
JT  - The Pediatric infectious disease journal
JID - 8701858
SB  - IM
MH  - Adolescent
MH  - Bartonella henselae/isolation & purification/pathogenicity
MH  - Cat-Scratch Disease/complications/*diagnosis/pathology
MH  - Child
MH  - Echocardiography
MH  - Endocarditis, Bacterial/complications/*diagnosis/pathology
MH  - Heart/diagnostic imaging/physiopathology
MH  - Heart Defects, Congenital/complications/*diagnosis/pathology
MH  - Hepatomegaly/complications/diagnostic imaging/pathology
MH  - Humans
MH  - Liver/diagnostic imaging/pathology
MH  - Male
MH  - Pancytopenia/complications/diagnostic imaging/pathology
MH  - Spleen/diagnostic imaging/pathology
MH  - Splenomegaly/complications/diagnostic imaging/pathology
EDAT- 2017/04/14 06:00
MHDA- 2017/04/21 06:00
CRDT- 2017/04/14 06:00
AID - 10.1097/INF.0000000000001510 [doi]
AID - 00006454-201705000-00022 [pii]
PST - ppublish
SO  - Pediatr Infect Dis J. 2017 May;36(5):516-520. doi: 10.1097/INF.0000000000001510.

<?xml version="1.0" encoding="UTF-8"?>
<b:Sources SelectedStyle="" xmlns:b="http://schemas.openxmlformats.org/officeDocument/2006/bibliography"  xmlns="http://schemas.openxmlformats.org/officeDocument/2006/bibliography" >
</b:Sources>