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Analyses and treatments of postoperative nasal complications after endonasal transsphenoidal resection of pituitary neoplasms.

Abstract In this study, we analyze and discuss the treatments of postoperative nasal complications after endonasal transsphenoidal resection of pituitary neoplasms (PNs). We performed 129 endonasal transsphenoidal resections of PNs and analyzed and treated cases with nasal complications. After endonasal transsphenoidal resection of PNs, there were 26 cases of postoperative nasal complications (20.1%), including nasal hemorrhage (4.8%), cerebrospinal fluid rhinorrhea (6.9%), sphenoid sinusitis (2.3%), atrophic rhinitis (1.6%), olfactory disorder (1.6%), perforation of nasal septum (0.8%), and nasal adhesion (2.3%). All patients clinically recovered after therapy, which included treatment of the cavity through nasal endoscopy, intranasal corticosteroids, and nasal irrigation. We propose that regular nasal endoscopic review, specific nasal medications, and regular nasal irrigation can effectively clear nasal mucosal hyperemia-induced edema and nasal/nasoantral secretions, as well as promote regeneration of nasal mucosa, prevent nasal adhesion, maintain the sinus cavity drainage, and accelerate the recovery of the physiological function of the paranasal sinus. Timely treatment of patients with nasal complications after endonasal transsphenoidal resections of PNs could greatly relieve the clinical symptoms. Nasal cleaning is very beneficial to patients after surgery recovery.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title medicine
Publication Year Start




PMID- 28403108
OWN - NLM
STAT- MEDLINE
DA  - 20170413
DCOM- 20170427
LR  - 20170430
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 96
IP  - 15
DP  - 2017 Apr
TI  - Analyses and treatments of postoperative nasal complications after endonasal
      transsphenoidal resection of pituitary neoplasms.
PG  - e6614
LID - 10.1097/MD.0000000000006614 [doi]
AB  - In this study, we analyze and discuss the treatments of postoperative nasal
      complications after endonasal transsphenoidal resection of pituitary neoplasms
      (PNs). We performed 129 endonasal transsphenoidal resections of PNs and analyzed 
      and treated cases with nasal complications. After endonasal transsphenoidal
      resection of PNs, there were 26 cases of postoperative nasal complications
      (20.1%), including nasal hemorrhage (4.8%), cerebrospinal fluid rhinorrhea
      (6.9%), sphenoid sinusitis (2.3%), atrophic rhinitis (1.6%), olfactory disorder
      (1.6%), perforation of nasal septum (0.8%), and nasal adhesion (2.3%). All
      patients clinically recovered after therapy, which included treatment of the
      cavity through nasal endoscopy, intranasal corticosteroids, and nasal irrigation.
      We propose that regular nasal endoscopic review, specific nasal medications, and 
      regular nasal irrigation can effectively clear nasal mucosal hyperemia-induced
      edema and nasal/nasoantral secretions, as well as promote regeneration of nasal
      mucosa, prevent nasal adhesion, maintain the sinus cavity drainage, and
      accelerate the recovery of the physiological function of the paranasal sinus.
      Timely treatment of patients with nasal complications after endonasal
      transsphenoidal resections of PNs could greatly relieve the clinical symptoms.
      Nasal cleaning is very beneficial to patients after surgery recovery.
FAU - Cheng, You
AU  - Cheng Y
AD  - aDepartment of Otolaryngology-Head and Neck Surgery bDepartment of Neurosurgery
      cDepartment of Neurology, Jinling Hospital, Nanjing, Jiangsu, China.
FAU - Xue, Fei
AU  - Xue F
FAU - Wang, Tian-You
AU  - Wang TY
FAU - Ji, Jun-Feng
AU  - Ji JF
FAU - Chen, Wei
AU  - Chen W
FAU - Wang, Zhi-Yi
AU  - Wang ZY
FAU - Xu, Li
AU  - Xu L
FAU - Hang, Chun-Hua
AU  - Hang CH
FAU - Liu, Xin-Feng
AU  - Liu XF
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - AIM
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aftercare/methods
MH  - Aged
MH  - Cerebrospinal Fluid Rhinorrhea/etiology/therapy
MH  - Child
MH  - Epistaxis/etiology/therapy
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Nasal Lavage/*methods
MH  - Nasal Mucosa/pathology
MH  - Nasal Septal Perforation/etiology/therapy
MH  - Nasal Surgical Procedures/methods
MH  - Natural Orifice Endoscopic Surgery/*adverse effects/methods
MH  - Nose/injuries/surgery
MH  - Nose Diseases/etiology/*therapy
MH  - Olfactory Nerve Diseases/etiology/therapy
MH  - Paranasal Sinuses/physiopathology
MH  - Pituitary Neoplasms/*surgery
MH  - Postoperative Complications/etiology/*therapy
MH  - Recovery of Function
MH  - Retrospective Studies
MH  - Rhinitis, Atrophic/etiology/therapy
MH  - Sphenoid Sinus/surgery
MH  - Sphenoid Sinusitis/etiology/therapy
MH  - Tissue Adhesions/etiology/therapy
MH  - Young Adult
PMC - PMC5403105
EDAT- 2017/04/14 06:00
MHDA- 2017/04/28 06:00
CRDT- 2017/04/14 06:00
AID - 10.1097/MD.0000000000006614 [doi]
AID - 00005792-201704140-00041 [pii]
PST - ppublish
SO  - Medicine (Baltimore). 2017 Apr;96(15):e6614. doi: 10.1097/MD.0000000000006614.

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