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Case Management of Dengue: Lessons Learned.

Abstract The global burden of dengue and its geographic distribution have increased over the past several decades. The introduction of dengue in new areas has often been accompanied by high case-fatality rates. Drawing on the experience in managing dengue cases at the Queen Sirikit National Institute of Child Health in Bangkok, Thailand, this article provides the authors' perspectives on key clinical lessons to improve dengue-related outcomes. Parallels between this clinical experience and outcomes reported in randomized controlled trials, results of efforts to disseminate practice recommendations, and suggestions for areas for further research are also discussed.
PMID
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Authors

Mayor MeshTerms
Keywords

case management

case-fatality rate.

clinical care

dengue

hemorrhage

plasma leakage

Journal Title the journal of infectious diseases
Publication Year Start




PMID- 28403440
OWN - NLM
STAT- MEDLINE
DA  - 20170413
DCOM- 20170420
LR  - 20170420
IS  - 1537-6613 (Electronic)
IS  - 0022-1899 (Linking)
VI  - 215
IP  - suppl_2
DP  - 2017 Mar 01
TI  - Case Management of Dengue: Lessons Learned.
PG  - S79-S88
LID - 10.1093/infdis/jiw609 [doi]
AB  - The global burden of dengue and its geographic distribution have increased over
      the past several decades. The introduction of dengue in new areas has often been 
      accompanied by high case-fatality rates. Drawing on the experience in managing
      dengue cases at the Queen Sirikit National Institute of Child Health in Bangkok, 
      Thailand, this article provides the authors' perspectives on key clinical lessons
      to improve dengue-related outcomes. Parallels between this clinical experience
      and outcomes reported in randomized controlled trials, results of efforts to
      disseminate practice recommendations, and suggestions for areas for further
      research are also discussed.
CI  - (c) The Author 2017. Published by Oxford University Press for the Infectious
      Diseases Society of America. All rights reserved. For permissions, e-mail:
      [email protected]
FAU - Kalayanarooj, Siripen
AU  - Kalayanarooj S
AD  - Dengue Unit, Queen Sirikit National Institute of Child Health, Bangkok, Thailand;
      and.
FAU - Rothman, Alan L
AU  - Rothman AL
AD  - Department of Cell and Molecular Biology and Institute for Immunology and
      Informatics, University of Rhode Island, Providence.
FAU - Srikiatkhachorn, Anon
AU  - Srikiatkhachorn A
AD  - Dengue Unit, Queen Sirikit National Institute of Child Health, Bangkok, Thailand 
      ; and.
AD  - Department of Cell and Molecular Biology and Institute for Immunology and
      Informatics, University of Rhode Island, Providence.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - J Infect Dis
JT  - The Journal of infectious diseases
JID - 0413675
RN  - 0 (Biomarkers)
SB  - AIM
SB  - IM
MH  - Biomarkers/blood
MH  - Case Management
MH  - Child
MH  - Dengue/blood/diagnosis/mortality/*therapy
MH  - Early Diagnosis
MH  - Fluid Therapy
MH  - Humans
MH  - Thailand/epidemiology
OTO - NOTNLM
OT  - case management
OT  - case-fatality rate.
OT  - clinical care
OT  - dengue
OT  - hemorrhage
OT  - plasma leakage
EDAT- 2017/04/14 06:00
MHDA- 2017/04/21 06:00
CRDT- 2017/04/14 06:00
AID - 3574517 [pii]
AID - 10.1093/infdis/jiw609 [doi]
PST - ppublish
SO  - J Infect Dis. 2017 Mar 1;215(suppl_2):S79-S88. doi: 10.1093/infdis/jiw609.

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