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PMID- 28403761
DA  - 20170413
DCOM- 20170419
LR  - 20170419
IS  - 1326-5377 (Electronic)
IS  - 0025-729X (Linking)
VI  - 206
IP  - 7
DP  - 2017 Apr 17
TI  - Trends in the prevalence of hepatitis B infection among women giving birth in New
      South Wales.
PG  - 301-305
AB  - OBJECTIVES: To evaluate the effect of targeted and catch-up hepatitis B virus
      (HBV) vaccination programs in New South Wales on HBV prevalence among women
      giving birth for the first time. DESIGN: Observational study linking data from
      the NSW Perinatal Data Collection for women giving birth during 2000-2012 with
      HBV notifications in the NSW Notifiable Conditions Information Management System.
      MAIN OUTCOME MEASURES: HBV prevalence in Indigenous Australian, non-Indigenous
      Australian-born, and overseas-born women giving birth. RESULTS: Of 482 944 women 
      who gave birth to their first child, 3383 (0.70%) were linked to an HBV
      notification. HBV prevalence was 1.95% (95% CI, 1.88-2.02%) among overseas-born
      women, 0.79% (95% CI, 0.63-0.95%) among Indigenous Australian women, and 0.11%
      (95% CI, 0.09-0.12%) among non-Indigenous Australian-born women. In Indigenous
      Australian women, prevalence was significantly lower for those who had been
      eligible for inclusion in the targeted at-risk newborn or universal school-based 
      vaccination programs (maternal year of birth, 1992-1999: 0.15%) than for those
      who were not (born </= 1981: 1.31%; for trend, P < 0.001). There was no
      statistically significant downward trend among non-Indigenous Australian-born or 
      overseas-born women. HBV prevalence was higher among Indigenous women residing in
      regional and remote areas than those in major cities (adjusted odds ratio [aOR], 
      2.23; 95% CI, 1.40-3.57), but lower for non-Indigenous (aOR, 0.39; 95% CI,
      0.28-0.55) and overseas-born women (aOR, 0.61; 95% CI, 0.49-0.77). CONCLUSION:
      Among women giving birth, there was a significant reduction in HBV prevalence in 
      Indigenous women associated with the introduction of the HBV vaccination program 
      in NSW, although prevalence remains higher than among non-Indigenous
      Australian-born women, and it also varies by region of residence. Continuing
      evaluation is needed to ensure that the prevalence of HBV infections continues to
      fall in Australia.
FAU - Deng, Lucy
AU  - Deng L
AD  - UNSW Sydney, Sydney, NSW [email protected]
FAU - Reekie, Joanne
AU  - Reekie J
AD  - The Kirby Institute, UNSW Sydney, Sydney, NSW.
FAU - Ward, James S
AU  - Ward JS
AD  - South Australian Health and Medical Research Institute, Adelaide, SA.
FAU - Hayen, Andrew
AU  - Hayen A
AD  - UNSW Sydney, Sydney, NSW.
FAU - Kaldor, John M
AU  - Kaldor JM
AD  - The Kirby Institute, UNSW Sydney, Sydney, NSW.
FAU - Kong, Marlene
AU  - Kong M
AD  - The Kirby Institute, UNSW Sydney, Sydney, NSW.
FAU - Hunt, Jennifer M
AU  - Hunt JM
AD  - Aboriginal Health and Medical Research Council, Sydney, NSW.
FAU - Liu, Bette
AU  - Liu B
AD  - UNSW Sydney, Sydney, NSW.
LA  - eng
PT  - Journal Article
PT  - Observational Study
PL  - Australia
TA  - Med J Aust
JT  - The Medical journal of Australia
JID - 0400714
SB  - IM
MH  - Adult
MH  - Child
MH  - Female
MH  - Hepatitis B/*epidemiology/prevention & control
MH  - Hepatitis B virus
MH  - Humans
MH  - Immunization Programs
MH  - Infant, Newborn
MH  - Logistic Models
MH  - Mass Vaccination/*statistics & numerical data
MH  - New South Wales/epidemiology
MH  - Oceanic Ancestry Group/*statistics & numerical data
MH  - Odds Ratio
MH  - Parity
MH  - Population Groups/*statistics & numerical data
MH  - Pregnancy
MH  - Pregnancy Complications, Infectious/*epidemiology/prevention & control/virology
MH  - Registries
MH  - Young Adult
EDAT- 2017/04/14 06:00
MHDA- 2017/04/20 06:00
CRDT- 2017/04/14 06:00
PHST- 2016/07/12 [received]
PHST- 2016/10/18 [accepted]
AID - 10.5694/mja16.00823 [pii]
PST - ppublish
SO  - Med J Aust. 2017 Apr 17;206(7):301-305.

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