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PMID- 28406960
OWN - NLM
STAT- MEDLINE
DA  - 20170413
DCOM- 20170420
LR  - 20170420
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 12
IP  - 4
DP  - 2017
TI  - Translation and validation of the Serbian primary biliary cholangitis-40
      questionnaire.
PG  - e0175697
LID - 10.1371/journal.pone.0175697 [doi]
AB  - BACKGROUND AND AIMS: To translate into Serbian and validate the Primary Biliary
      Cholangitis-40 (PBC-40) and PBC-27 questionnaires. MATERIALS AND METHODS:
      Ninety-four consecutive outpatients with the diagnosis of PBC from three
      departments across two tertiary care institutions in Belgrade were enrolled from 
      February to October 2016. Standard methodology for cultural adaption of
      healthcare related quality of life questionnaires was used, and included: a
      forward translation, backward translation and a pilot test of the Serbian PBC-40 
      on five patients who gave suggestions and comments. For evaluation of the
      questionnaires, acceptance was shown by the proportion of missing items and the
      internal consistency was assessed using Cronbach's alpha coefficient. The PBC-40 
      was self-administered under the supervision of an experienced hepatologist. The
      PBC-27 is a shorter version of the PBC-40. RESULTS: A total of 92 (97.9%) of the 
      patients were females. The mean age was 59.26 +/- 1.05 years and the average
      length of disease was 60.45 +/- 48.314 months. The average PBC-40 score was 85.62
      +/- 30.46. The total time needed to complete the questionnaire ranged from 7 to
      16 minutes. The proportion of missing items was 5.45% (205/3760). Cronbach's
      alpha for the entire scale was 0.93. Reliability for all of the domains of the
      PBC-40 was above 0.70, except for the domain "Symptoms" (alpha = 0.52). Overall
      reliability of the PBC-27 was alpha = 0.90. Domains "Dryness", "Symptoms" and
      "Fatigue" demonstrated reliability below alpha = 0.70. CONCLUSIONS: The Serbian
      PBC-40 is a valid and reasonably adequate for use in Serbian PBC patients. The
      PBC-40 is preferred over the PBC-27.
FAU - Zec, Simon
AU  - Zec S
AUID- ORCID: http://orcid.org/0000-0002-4353-8535
AD  - Department of Internal Medicine, School of Medicine, University of Belgrade,
      Belgrade, Serbia.
FAU - Popovic, Dusan
AU  - Popovic D
AD  - Department of Internal Medicine, School of Medicine, University of Belgrade,
      Belgrade, Serbia.
AD  - Clinic for Gastroenterology and Hepatology, Clinical Center of Serbia, Belgrade, 
      Serbia.
FAU - Matovic, Vera
AU  - Matovic V
AD  - Clinic for Gastroenterology and Hepatology, Clinical Center of Serbia, Belgrade, 
      Serbia.
FAU - Nikolic, Vladimir
AU  - Nikolic V
AD  - Department of Internal Medicine, School of Medicine, University of Belgrade,
      Belgrade, Serbia.
FAU - Bojovic, Ksenija
AU  - Bojovic K
AD  - Department of Internal Medicine, School of Medicine, University of Belgrade,
      Belgrade, Serbia.
AD  - Department of Gastroenterology and Hepatology, Clinic for Tropical and Infectious
      Diseases, Clinical Center of Serbia, Belgrade, Serbia.
FAU - Jovic, Jasna
AU  - Jovic J
AD  - Department of Gastroenterology and Hepatology, Military Medical Academy,
      Belgrade, Serbia.
FAU - Markovic Denic, Ljiljana
AU  - Markovic Denic L
AD  - Department of Internal Medicine, School of Medicine, University of Belgrade,
      Belgrade, Serbia.
AD  - Institute of Epidemiology, School of Medicine, University of Belgrade, Belgrade, 
      Serbia.
FAU - Milosavljevic, Tomica
AU  - Milosavljevic T
AD  - Department of Internal Medicine, School of Medicine, University of Belgrade,
      Belgrade, Serbia.
AD  - Clinic for Gastroenterology and Hepatology, Clinical Center of Serbia, Belgrade, 
      Serbia.
FAU - Alempijevic, Tamara
AU  - Alempijevic T
AD  - Department of Internal Medicine, School of Medicine, University of Belgrade,
      Belgrade, Serbia.
AD  - Clinic for Gastroenterology and Hepatology, Clinical Center of Serbia, Belgrade, 
      Serbia.
LA  - eng
PT  - Journal Article
PT  - Validation Studies
DEP - 20170413
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
MH  - Cholangitis/*epidemiology
MH  - Comprehension
MH  - Cross-Sectional Studies
MH  - Cultural Characteristics
MH  - Female
MH  - Humans
MH  - Male
MH  - Quality of Life
MH  - Reproducibility of Results
MH  - *Self Report
MH  - Serbia/epidemiology
MH  - *Translations
EDAT- 2017/04/14 06:00
MHDA- 2017/04/21 06:00
CRDT- 2017/04/14 06:00
PHST- 2016/12/26 [received]
PHST- 2017/03/29 [accepted]
AID - 10.1371/journal.pone.0175697 [doi]
AID - PONE-D-16-51034 [pii]
PST - epublish
SO  - PLoS One. 2017 Apr 13;12(4):e0175697. doi: 10.1371/journal.pone.0175697.
      eCollection 2017.

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