PubTransformer

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PMID- 28407812
OWN - NLM
STAT- MEDLINE
DA  - 20170414
DCOM- 20170425
LR  - 20170425
IS  - 1756-3305 (Electronic)
IS  - 1756-3305 (Linking)
VI  - 10
IP  - 1
DP  - 2017 Apr 13
TI  - Diagnostic antigens for visceral leishmaniasis: clarification of nomenclatures.
PG  - 178
LID - 10.1186/s13071-017-2120-x [doi]
AB  - BACKGROUND: Stimulated by the increasing recent use of 'K' or 'rK' nomenclature
      for antigens reported for visceral leishmaniasis (VL) diagnostic serology, we
      wished to give a chronological synopsis of their reporting and the potentially
      confusing terminology. METHODS: The literature was examined for 'K' or 'rK'
      terminology for VL diagnostic antigens, with emphasis on the original
      publications in which terms were first used. RESULTS: A chronological account of 
      the first use of these 'K' and 'rK' nomenclatures was compiled. Since the
      original use of this terminology in 1993 in the name rK39 for a Leishmania
      antigen fragment, we found nine subsequent instances where 'K' or 'rK' have been 
      used to maintain consistency with this nomenclature. We also found instances
      where there were ambiguities regarding reported strain name, origin and GenBank
      accession numbers. CONCLUSIONS: We have documented here the uses in the
      literature of the 'K' or 'rK' prefix for VL diagnostic antigen nomenclature. We
      suggest that, to avoid confusion, the use of such nomenclature for future
      antigens should either provide the logical derivation of the term or indicate
      that the designation is entirely empirical.
FAU - Bhattacharyya, Tapan
AU  - Bhattacharyya T
AD  - Department of Pathogen Molecular Biology, Faculty of Infectious and Tropical
      Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
      [email protected]
FAU - Marlais, Tegwen
AU  - Marlais T
AD  - Department of Pathogen Molecular Biology, Faculty of Infectious and Tropical
      Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
FAU - Miles, Michael A
AU  - Miles MA
AD  - Department of Pathogen Molecular Biology, Faculty of Infectious and Tropical
      Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20170413
PL  - England
TA  - Parasit Vectors
JT  - Parasites & vectors
JID - 101462774
RN  - 0 (Antigens, Protozoan)
SB  - IM
MH  - Antigens, Protozoan/*immunology
MH  - Leishmaniasis, Visceral/*diagnosis
MH  - Serologic Tests/*methods
MH  - *Terminology as Topic
PMC - PMC5390433
OTO - NOTNLM
OT  - Antigens
OT  - Diagnostics
OT  - HASPB
OT  - Kinesin
OT  - Leishmania
OT  - Nomenclature
OT  - Serology
OT  - Visceral leishmaniasis
OT  - rK28
OT  - rK39
EDAT- 2017/04/15 06:00
MHDA- 2017/04/26 06:00
CRDT- 2017/04/15 06:00
PHST- 2016/12/13 [received]
PHST- 2017/03/29 [accepted]
AID - 10.1186/s13071-017-2120-x [doi]
AID - 10.1186/s13071-017-2120-x [pii]
PST - epublish
SO  - Parasit Vectors. 2017 Apr 13;10(1):178. doi: 10.1186/s13071-017-2120-x.

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