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PMID- 28412961
OWN - NLM
STAT- MEDLINE
DA  - 20170417
DCOM- 20170517
LR  - 20170517
IS  - 1749-8090 (Electronic)
IS  - 1749-8090 (Linking)
VI  - 12
IP  - 1
DP  - 2017 Apr 17
TI  - Perventricular double-device closure of wide-spaced multi-hole perimembranous
      ventricular septal defect.
PG  - 24
LID - 10.1186/s13019-017-0585-5 [doi]
AB  - BACKGROUND: Device closure of a wide-spaced multi-hole PmVSD is difficult to
      succeed in percutaneous approach. This study is to evaluate the feasibility,
      safety and efficacy of perventricular device closure of wide-spaced multi-hole
      PmVSD using a double-device implanting technique. METHODS: Sixteen patients with 
      wide-spaced multi-hole PmVSD underwent perventricular closure with two devices
      through an inferior median sternotomy approach under transesophageal
      echocardiographic guidance. The largest hole and its adjacent small holes were
      occluded with an optimal-sized device. The far-away residual hole was occluded
      with the other device using a probe-assisted delivery system. All patients were
      followed up for a period of 1 to 4 years to determine the residual shunt,
      atrioventricular block and the adjacent valvular function. RESULTS: The number of
      the holes of the PmVSD was 2 to 4. The maximum distance between the holes was 5.0
      to 10.0 mm (median, 6.4 mm). The diameter of the largest hole was 2.5 to 7.0 mm
      (median, 3.6 mm). The success rate of double-device closure was 100%. Immediate
      residual shunts were found in 6 patients (38%), and incomplete right bundle
      branch block at discharge occurred in 3 cases (19%). Both complications decreased
      to 6% at 1-year follow-up. Neither of them had a severe device-related
      complication. CONCLUSIONS: Perventricular closure of a wide-spaced multi-hole
      PmVSD using a double-device implanting technique is feasible, safe, and
      efficacious. In multi-hole PmVSDs with the distance between the holes of more
      than 5 mm, double-device implantation may achieve a complete occlusion.
FAU - Liang, Fei
AU  - Liang F
AD  - Department of Cardiovascular Surgery, Provincial Hospital Affiliated to Shandong 
      University, No. 324 Jingwu Road, Jinan, 250021, China.
FAU - Hongxin, Li
AU  - Hongxin L
AD  - Department of Cardiovascular Surgery, Provincial Hospital Affiliated to Shandong 
      University, No. 324 Jingwu Road, Jinan, 250021, China. [email protected]
FAU - Zhang, Hai-Zhou
AU  - Zhang HZ
AD  - Department of Cardiovascular Surgery, Provincial Hospital Affiliated to Shandong 
      University, No. 324 Jingwu Road, Jinan, 250021, China.
FAU - Wenbin, Guo
AU  - Wenbin G
AD  - Ultrasound Department, Provincial Hospital Affiliated to Shandong University,
      Jinan, China.
FAU - Zou, Cheng-Wei
AU  - Zou CW
AD  - Department of Cardiovascular Surgery, Provincial Hospital Affiliated to Shandong 
      University, No. 324 Jingwu Road, Jinan, 250021, China.
FAU - Farhaj, Zeeshan
AU  - Farhaj Z
AD  - Department of Cardiovascular Surgery, Provincial Hospital Affiliated to Shandong 
      University, No. 324 Jingwu Road, Jinan, 250021, China.
LA  - eng
PT  - Journal Article
DEP - 20170417
PL  - England
TA  - J Cardiothorac Surg
JT  - Journal of cardiothoracic surgery
JID - 101265113
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Cardiac Catheterization/*methods
MH  - Cardiac Surgical Procedures/*instrumentation
MH  - Child
MH  - Child, Preschool
MH  - Echocardiography
MH  - Equipment Design
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Septal Defects, Ventricular/diagnosis/*surgery
MH  - Humans
MH  - Infant
MH  - Male
MH  - Radiography, Thoracic
MH  - Retrospective Studies
MH  - *Septal Occluder Device
MH  - Treatment Outcome
MH  - Young Adult
PMC - PMC5392910
OTO - NOTNLM
OT  - Device closure
OT  - Echocardiography
OT  - Perimembranous ventricular septal defect
OT  - Perventricular
EDAT- 2017/04/18 06:00
MHDA- 2017/05/18 06:00
CRDT- 2017/04/18 06:00
PHST- 2016/10/14 [received]
PHST- 2017/03/21 [accepted]
AID - 10.1186/s13019-017-0585-5 [doi]
AID - 10.1186/s13019-017-0585-5 [pii]
PST - epublish
SO  - J Cardiothorac Surg. 2017 Apr 17;12(1):24. doi: 10.1186/s13019-017-0585-5.

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