PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

Simultaneous bilateral cochlear implants: Developmental advances do not yet achieve normal cortical processing.

Abstract Simultaneous bilateral cochlear implantation promotes symmetric development of bilateral auditory pathways but binaural hearing remains abnormal. To evaluate whether bilateral cortical processing remains impaired in such children, cortical activity to unilateral and bilateral stimuli was assessed in a unique cohort of 16 children who received bilateral cochlear implants (CIs) simultaneously at 1.97 ± 0.86 years of age and had ~4 years of CI experience, providing the first opportunity to assess electrically driven cortical development in the absence of reorganized asymmetries from sequential implantation.
PMID
Related Publications

Binaural fusion and listening effort in children who use bilateral cochlear implants: a psychoacoustic and pupillometric study.

Lateralization of interimplant timing and level differences in children who use bilateral cochlear implants.

Early unilateral cochlear implantation promotes mature cortical asymmetries in adolescents who are deaf.

Bilateral input protects the cortex from unilaterally-driven reorganization in children who are deaf.

Cortical Representation of Interaural Time Difference Is Impaired by Deafness in Development: Evidence from Children with Early Long-term Access to Sound through Bilateral Cochlear Implants Provided Simultaneously.

Authors

Mayor MeshTerms
Keywords

auditory brain

beamformer

bilateral cochlear implant

children

cortical aural preference

cortical lateralization

development

electro‐encephalogram

hearing loss

speech perception

Journal Title brain and behavior
Publication Year Start




PMID- 28413698
OWN - NLM
STAT- MEDLINE
DA  - 20170417
DCOM- 20170424
LR  - 20170424
IS  - 2162-3279 (Electronic)
VI  - 7
IP  - 4
DP  - 2017 Apr
TI  - Simultaneous bilateral cochlear implants: Developmental advances do not yet
      achieve normal cortical processing.
PG  - e00638
LID - 10.1002/brb3.638 [doi]
AB  - BACKGROUND: Simultaneous bilateral cochlear implantation promotes symmetric
      development of bilateral auditory pathways but binaural hearing remains abnormal.
      To evaluate whether bilateral cortical processing remains impaired in such
      children, cortical activity to unilateral and bilateral stimuli was assessed in a
      unique cohort of 16 children who received bilateral cochlear implants (CIs)
      simultaneously at 1.97 +/- 0.86 years of age and had ~4 years of CI experience,
      providing the first opportunity to assess electrically driven cortical
      development in the absence of reorganized asymmetries from sequential
      implantation. METHODS: Cortical activity to unilateral and bilateral stimuli was 
      measured using multichannel electro-encephalography. Cortical processing in
      children with bilateral CIs was compared with click-elicited activity in 13
      normal hearing children matched for time-in-sound. Source activity was localized 
      using the Time Restricted, Artefact and Coherence source Suppression (TRACS)
      beamformer method. RESULTS: Consistent with dominant crossed auditory pathways,
      normal P1 activity (~100 ms) was weaker to ipsilateral stimuli relative to
      contralateral and bilateral stimuli and both auditory cortices preferentially
      responded to the contralateral ear. Right hemisphere dominance was evident
      overall. Children with bilateral CIs maintained the expected right dominance but 
      differences from normal included: (i) minimal changes between ipsilateral,
      contralateral and bilateral stimuli, (ii) weaker than normal contralateral
      stimulus preference, (iii) symmetric activity to bilateral stimuli, and (iv)
      increased occipital lobe recruitment during bilateral relative to unilateral
      stimulation. Between-group contrasts demonstrated lower than normal activity in
      the inferior parieto-occipital lobe (suggesting deficits in sensory integration) 
      and greater than normal left frontal lobe activity (suggesting increased
      attention), even during passive listening. CONCLUSIONS: Together, findings
      suggest that early simultaneous bilateral cochlear implantation promotes
      normal-like auditory symmetry but that abnormalities in cortical processing
      consequent to deafness and/or electrical stimulation through two independent
      speech processors persist.
FAU - Easwar, Vijayalakshmi
AU  - Easwar V
AUID- ORCID: 0000-0001-7944-3012
AD  - Archie's Cochlear Implant LaboratoryThe Hospital for Sick
      ChildrenTorontoONCanada.
AD  - Collaborative Program in NeuroscienceThe University of TorontoTorontoONCanada.
FAU - Yamazaki, Hiroshi
AU  - Yamazaki H
AD  - Archie's Cochlear Implant LaboratoryThe Hospital for Sick
      ChildrenTorontoONCanada.
FAU - Deighton, Michael
AU  - Deighton M
AD  - Archie's Cochlear Implant LaboratoryThe Hospital for Sick
      ChildrenTorontoONCanada.
FAU - Papsin, Blake
AU  - Papsin B
AD  - OtolaryngologyThe University of TorontoTorontoONCanada.
AD  - OtolaryngologyThe Hospital for Sick ChildrenTorontoONCanada.
FAU - Gordon, Karen
AU  - Gordon K
AUID- ORCID: 0000-0002-2491-3125
AD  - Archie's Cochlear Implant LaboratoryThe Hospital for Sick
      ChildrenTorontoONCanada.
AD  - OtolaryngologyThe University of TorontoTorontoONCanada.
LA  - eng
PT  - Journal Article
DEP - 20170228
PL  - United States
TA  - Brain Behav
JT  - Brain and behavior
JID - 101570837
SB  - IM
MH  - Acoustic Stimulation/methods
MH  - Auditory Pathways/physiopathology
MH  - Auditory Perception/*physiology
MH  - Brain/*physiopathology
MH  - Brain Mapping
MH  - Child
MH  - Child, Preschool
MH  - Cochlear Implantation/*methods
MH  - Cochlear Implants
MH  - Cohort Studies
MH  - Deafness/*physiopathology/*rehabilitation
MH  - Electroencephalography
MH  - Female
MH  - Functional Laterality/*physiology
MH  - Hearing Tests/methods
MH  - Humans
MH  - Male
MH  - Treatment Outcome
PMC - PMC5390830
OTO - NOTNLM
OT  - auditory brain
OT  - beamformer
OT  - bilateral cochlear implant
OT  - children
OT  - cortical aural preference
OT  - cortical lateralization
OT  - development
OT  - electro-encephalogram
OT  - hearing loss
OT  - speech perception
EDAT- 2017/04/18 06:00
MHDA- 2017/04/25 06:00
CRDT- 2017/04/18 06:00
PHST- 2016/08/17 [received]
PHST- 2016/11/15 [revised]
PHST- 2016/12/18 [accepted]
AID - 10.1002/brb3.638 [doi]
AID - BRB3638 [pii]
PST - epublish
SO  - Brain Behav. 2017 Feb 28;7(4):e00638. doi: 10.1002/brb3.638. eCollection 2017
      Apr.

<?xml version="1.0" encoding="UTF-8"?>
<b:Sources SelectedStyle="" xmlns:b="http://schemas.openxmlformats.org/officeDocument/2006/bibliography"  xmlns="http://schemas.openxmlformats.org/officeDocument/2006/bibliography" >
</b:Sources>