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Progress in vaccination towards hepatitis B control and elimination in the Region of the Americas.

Abstract Over recent decades, the Region of the Americas has made significant progress towards hepatitis B elimination. We summarize the countries/territories' efforts in introducing and implementing hepatitis B (HB) vaccination and in evaluating its impact on HB virus seroprevalence.
PMID
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Authors

Mayor MeshTerms
Keywords

Birth dose

Hepatitis B elimination

Hepatitis B vaccine

Mother-to-child-transmission

Region of the Americas

Journal Title bmc public health
Publication Year Start




PMID- 28415981
OWN - NLM
STAT- In-Process
DA  - 20170418
LR  - 20170421
IS  - 1471-2458 (Electronic)
IS  - 1471-2458 (Linking)
VI  - 17
IP  - 1
DP  - 2017 Apr 17
TI  - Progress in vaccination towards hepatitis B control and elimination in the Region
      of the Americas.
PG  - 325
LID - 10.1186/s12889-017-4227-6 [doi]
AB  - BACKGROUND: Over recent decades, the Region of the Americas has made significant 
      progress towards hepatitis B elimination. We summarize the countries/territories'
      efforts in introducing and implementing hepatitis B (HB) vaccination and in
      evaluating its impact on HB virus seroprevalence. METHODS: We collected
      information about HB vaccination schedules, coverage estimates, and year of
      vaccine introduction from countries/territories reporting to the Pan American
      Health Organization/World Health Organization (PAHO/WHO) through the WHO/UNICEF
      Joint Reporting Form on Immunization. We obtained additional information
      regarding countries/territories vaccination recommendations and strategies
      through communications with Expanded Program on Immunization (EPI) managers and
      national immunization survey reports. We identified vaccine impact studies
      conducted and published in the Americas. RESULTS: As of October 2016, all 51
      countries/territories have included infant HB vaccination in their official
      immunization schedule. Twenty countries, whose populations represent over 90% of 
      the Region's births, have included nationwide newborn HB vaccination. We
      estimated at 89% and 75%, the regional three-dose series and the birth dose HB
      vaccination coverage, respectively, for 2015. The impact evaluations of infant HB
      immunization programs in the Region have shown substantial reductions in HB
      surface antigen (HBsAg) seroprevalence. CONCLUSION: The achievements of
      vaccination programs in the Americas suggest that the elimination of perinatal
      and early childhood HB transmission could be feasible in the short-term.
      Moreover, the data gathered indicate that the Region may have already achieved
      the 2020 WHO goal for HB control.
FAU - Ropero Alvarez, Alba Maria
AU  - Ropero Alvarez AM
AD  - Unit of Comprehensive Family Immunization. Department of Family, Gender and Life 
      Course, Pan American Health Organization (PAHO/WHO), 525 23rd St. Nw, Washington 
      DC, 20037, USA. [email protected]
FAU - Perez-Vilar, Silvia
AU  - Perez-Vilar S
AD  - Current address: U.S. Food and Drug Administration, 10903 New Hampshire Ave,
      Silver Spring, MD, 20993, USA.
FAU - Pacis-Tirso, Carmelita
AU  - Pacis-Tirso C
AD  - Unit of Comprehensive Family Immunization. Department of Family, Gender and Life 
      Course, Pan American Health Organization (PAHO/WHO), 525 23rd St. Nw, Washington 
      DC, 20037, USA.
FAU - Contreras, Marcela
AU  - Contreras M
AD  - Unit of Comprehensive Family Immunization. Department of Family, Gender and Life 
      Course, Pan American Health Organization (PAHO/WHO), 525 23rd St. Nw, Washington 
      DC, 20037, USA.
FAU - El Omeiri, Nathalie
AU  - El Omeiri N
AD  - Unit of Comprehensive Family Immunization. Department of Family, Gender and Life 
      Course, Pan American Health Organization (PAHO/WHO), 525 23rd St. Nw, Washington 
      DC, 20037, USA.
FAU - Ruiz-Matus, Cuauhtemoc
AU  - Ruiz-Matus C
AD  - Unit of Comprehensive Family Immunization. Department of Family, Gender and Life 
      Course, Pan American Health Organization (PAHO/WHO), 525 23rd St. Nw, Washington 
      DC, 20037, USA.
FAU - Velandia-Gonzalez, Martha
AU  - Velandia-Gonzalez M
AD  - Unit of Comprehensive Family Immunization. Department of Family, Gender and Life 
      Course, Pan American Health Organization (PAHO/WHO), 525 23rd St. Nw, Washington 
      DC, 20037, USA.
LA  - eng
PT  - Journal Article
DEP - 20170417
PL  - England
TA  - BMC Public Health
JT  - BMC public health
JID - 100968562
PMC - PMC5392937
OTO - NOTNLM
OT  - Birth dose
OT  - Hepatitis B elimination
OT  - Hepatitis B vaccine
OT  - Mother-to-child-transmission
OT  - Region of the Americas
EDAT- 2017/04/19 06:00
MHDA- 2017/04/19 06:00
CRDT- 2017/04/19 06:00
PHST- 2016/10/31 [received]
PHST- 2017/04/05 [accepted]
AID - 10.1186/s12889-017-4227-6 [doi]
AID - 10.1186/s12889-017-4227-6 [pii]
PST - epublish
SO  - BMC Public Health. 2017 Apr 17;17(1):325. doi: 10.1186/s12889-017-4227-6.

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