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Low Fluence Photodynamic Therapy Versus Graded Subthreshold Transpupillary Thermotherapy for Chronic Central Serous Chorioretinopathy: Results From a Prospective Study.

Abstract The authors compare low fluence photodynamic therapy (PDT) against graded subthreshold transpupillary thermotherapy (TTT) for chronic central serous chorioretinopathy (CSC).
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Visual Acuity

Keywords
Journal Title ophthalmic surgery, lasers & imaging retina
Publication Year Start




PMID- 28419399
OWN - NLM
STAT- MEDLINE
DA  - 20170418
DCOM- 20170502
LR  - 20170502
IS  - 2325-8179 (Electronic)
IS  - 2325-8160 (Linking)
VI  - 48
IP  - 4
DP  - 2017 Apr 01
TI  - Low Fluence Photodynamic Therapy Versus Graded Subthreshold Transpupillary
      Thermotherapy for Chronic Central Serous Chorioretinopathy: Results From a
      Prospective Study.
PG  - 334-338
LID - 10.3928/23258160-20170329-08 [doi]
AB  - BACKGROUND AND OBJECTIVE: The authors compare low fluence photodynamic therapy
      (PDT) against graded subthreshold transpupillary thermotherapy (TTT) for chronic 
      central serous chorioretinopathy (CSC). PATIENTS AND METHODS: Forty-two eyes of
      42 patients with chronic CSC were included in this prospective, nonrandomized,
      interventional trial. All patients were offered PDT as an initial intervention.
      If they declined PDT, TTT was offered. RESULTS: Twenty patients underwent PDT and
      22 underwent TTT. The difference in best-corrected visual acuity between the TTT 
      and PDT groups at baseline and at 6 months after treatment was not significant (P
      = .728). The mean foveal thickness decreased significantly in both groups (P =
      .001). However, patients in the TTT group required more treatments (P = .013) and
      longer time for resolution of the CSC (P = .013). CONCLUSIONS: Both PDT and TTT
      may be equally effective in the treatment of chronic CSC. Graded subthreshold TTT
      may be a cost-effective and safe alternative for PDT. [Ophthalmic Surg Lasers
      Imaging Retina. 2017;48:334-338.].
CI  - Copyright 2017, SLACK Incorporated.
FAU - Manayath, George J
AU  - Manayath GJ
FAU - Karandikar, Smita S
AU  - Karandikar SS
FAU - Narendran, Siddharth
AU  - Narendran S
FAU - Kumarswamy, Karan A
AU  - Kumarswamy KA
FAU - Saravanan, V R
AU  - Saravanan VR
FAU - Morris, Rodney J
AU  - Morris RJ
FAU - Venkatapathy, Narendran
AU  - Venkatapathy N
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PL  - United States
TA  - Ophthalmic Surg Lasers Imaging Retina
JT  - Ophthalmic surgery, lasers & imaging retina
JID - 101599215
RN  - 0 (Photosensitizing Agents)
SB  - IM
MH  - Central Serous Chorioretinopathy/diagnosis/*therapy
MH  - Choroid/pathology
MH  - Chronic Disease
MH  - Female
MH  - Fluorescein Angiography
MH  - Follow-Up Studies
MH  - Fundus Oculi
MH  - Humans
MH  - Hyperthermia, Induced/*methods
MH  - Male
MH  - Middle Aged
MH  - Photochemotherapy/*methods
MH  - Photosensitizing Agents/therapeutic use
MH  - Prospective Studies
MH  - Pupil
MH  - Retina/pathology
MH  - Time Factors
MH  - Treatment Outcome
MH  - *Visual Acuity
EDAT- 2017/04/19 06:00
MHDA- 2017/05/04 06:00
CRDT- 2017/04/19 06:00
PHST- 2016/07/10 [received]
PHST- 2017/02/22 [accepted]
AID - 10.3928/23258160-20170329-08 [doi]
PST - ppublish
SO  - Ophthalmic Surg Lasers Imaging Retina. 2017 Apr 1;48(4):334-338. doi:
      10.3928/23258160-20170329-08.

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