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Use of Evicel Fibrin Sealant in Optic Disc Pit-Associated Macular Detachment.

Abstract Optic disc pit is a rare congenital anomaly of the optic nerve. Retinal detachment is a common complication with poor outcomes. Many surgical alternatives have been described for the treatment of this condition, producing variable results. Herein, the authors describe four cases of optic disc pit-associated macular detachment managed with pars plana vitrectomy, fluid-air exchange, drainage of subretinal fluid through the optic disc pit, temporal peripapillary laser, and application of Evicel fibrin sealant (human) (Ethicon, Bridgewater, NJ) over the optic disc head. Case 1 showed stable visual acuity and improvement of subretinal fluid. Cases 2 and 3 showed visual acuity and subretinal fluid improvements. At the 1-week follow-up visit, Case 4 showed almost total subretinal fluid absorption. The sealant invariably disappeared between 1 and 2 weeks and was tolerated by all patients. This case series suggests that Evicel fibrin sealant may be considered as an adjunctive option in the surgical treatment of optic disc pit-associated maculopathy. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:358-363.].
PMID
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Authors

Mayor MeshTerms

Visual Acuity

Keywords
Journal Title ophthalmic surgery, lasers & imaging retina
Publication Year Start




PMID- 28419404
OWN - NLM
STAT- MEDLINE
DA  - 20170418
DCOM- 20170502
LR  - 20170502
IS  - 2325-8179 (Electronic)
IS  - 2325-8160 (Linking)
VI  - 48
IP  - 4
DP  - 2017 Apr 01
TI  - Use of Evicel Fibrin Sealant in Optic Disc Pit-Associated Macular Detachment.
PG  - 358-363
LID - 10.3928/23258160-20170329-13 [doi]
AB  - Optic disc pit is a rare congenital anomaly of the optic nerve. Retinal
      detachment is a common complication with poor outcomes. Many surgical
      alternatives have been described for the treatment of this condition, producing
      variable results. Herein, the authors describe four cases of optic disc
      pit-associated macular detachment managed with pars plana vitrectomy, fluid-air
      exchange, drainage of subretinal fluid through the optic disc pit, temporal
      peripapillary laser, and application of Evicel fibrin sealant (human) (Ethicon,
      Bridgewater, NJ) over the optic disc head. Case 1 showed stable visual acuity and
      improvement of subretinal fluid. Cases 2 and 3 showed visual acuity and
      subretinal fluid improvements. At the 1-week follow-up visit, Case 4 showed
      almost total subretinal fluid absorption. The sealant invariably disappeared
      between 1 and 2 weeks and was tolerated by all patients. This case series
      suggests that Evicel fibrin sealant may be considered as an adjunctive option in 
      the surgical treatment of optic disc pit-associated maculopathy. [Ophthalmic Surg
      Lasers Imaging Retina. 2017;48:358-363.].
CI  - Copyright 2017, SLACK Incorporated.
FAU - de Oliveira, Paulo Ricardo Chaves
AU  - de Oliveira PRC
FAU - Berger, Alan Richard
AU  - Berger AR
FAU - Chow, David Robert
AU  - Chow DR
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Ophthalmic Surg Lasers Imaging Retina
JT  - Ophthalmic surgery, lasers & imaging retina
JID - 101599215
RN  - 0 (Fibrin Tissue Adhesive)
SB  - IM
MH  - Adult
MH  - Eye Abnormalities/*complications/diagnosis
MH  - Female
MH  - Fibrin Tissue Adhesive/*therapeutic use
MH  - Humans
MH  - Laser Coagulation/*methods
MH  - Male
MH  - Optic Disk/*abnormalities
MH  - Retinal Detachment/diagnosis/etiology/*surgery
MH  - Tomography, Optical Coherence
MH  - *Visual Acuity
MH  - Vitrectomy/methods
MH  - Young Adult
EDAT- 2017/04/19 06:00
MHDA- 2017/05/04 06:00
CRDT- 2017/04/19 06:00
PHST- 2016/07/12 [received]
PHST- 2017/02/21 [accepted]
AID - 10.3928/23258160-20170329-13 [doi]
PST - ppublish
SO  - Ophthalmic Surg Lasers Imaging Retina. 2017 Apr 1;48(4):358-363. doi:
      10.3928/23258160-20170329-13.

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