PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

Gender Difference in the Prognostic Value of N-Terminal Pro-B Type Natriuretic Peptide in Patients With Heart Failure - A Report From the Korean Heart Failure Registry (KorHF).

Abstract Very little data is available to evaluate the gender-specific role of N-terminal pro-B type natriuretic peptide (NT-proBNP). This study was performed to investigate whether there is a gender difference in the prognostic value of NT-proBNP in patients hospitalized for heart failure (HF).Methods and Results:A total of 2,280 patients hospitalized with HF (67.9±14.3 years, 50.9% women) from the nationwide registry database were analyzed. Composite events including all-cause mortality and HF readmission were assessed. During the mean follow-up period of 1,245±824 days, there were 1,067 cases of composite events (49.7%). NT-proBNP levels were significantly higher in patients with events than those without in both genders (P<0.001 for each). A higher NT-proBNP level was an independent predictor of events (highest vs. lowest tertile: hazard ratio [HR], 1.74; 95% confidence interval [CI], 1.25-2.43; P=0.001) in men, even after controlling for potential confounders. However, NT-proBNP was not associated with the occurrence of composite events in women in the same multivariable analysis (P>0.05).
PMID
Related Publications

Reductions in N-Terminal Pro-Brain Natriuretic Peptide Levels Are Associated With Lower Mortality and Heart Failure Hospitalization Rates in Patients With Heart Failure With Mid-Range and Preserved Ejection Fraction.

Relative Importance of History of Heart Failure Hospitalization and N-Terminal Pro-B-Type Natriuretic Peptide Level as Predictors of Outcomes in Patients With Heart Failure and Preserved Ejection Fraction.

Long-term results of intensified, N-terminal-pro-B-type natriuretic peptide-guided versus symptom-guided treatment in elderly patients with heart failure: five-year follow-up from TIME-CHF.

Comparative prognostic value of plasma and urinary N-terminal pro-B-type natriuretic peptide in patients with acute destabilized heart failure.

Prognostic role of N-terminal pro-brain natriuretic peptide in asymptomatic hypertensive and diabetic patients in primary care: impact of age and gender : Results from the PROBE-HF study.

Authors

Mayor MeshTerms
Keywords

Gender

Heart failure

N-terminal pro-B type natriuretic peptide

Prognosis

Journal Title circulation journal : official journal of the japanese circulation society
Publication Year Start




PMID- 28442636
OWN - NLM
STAT- Publisher
DA  - 20170426
LR  - 20170426
IS  - 1347-4820 (Electronic)
IS  - 1346-9843 (Linking)
DP  - 2017 Apr 21
TI  - Gender Difference in the Prognostic Value of N-Terminal Pro-B Type Natriuretic
      Peptide in Patients With Heart Failure- A Report From the Korean Heart Failure
      Registry (KorHF).
LID - 10.1253/circj.CJ-16-1345 [doi]
AB  - BACKGROUND: Very little data is available to evaluate the gender-specific role of
      N-terminal pro-B type natriuretic peptide (NT-proBNP). This study was performed
      to investigate whether there is a gender difference in the prognostic value of
      NT-proBNP in patients hospitalized for heart failure (HF).Methods and Results:A
      total of 2,280 patients hospitalized with HF (67.9+/-14.3 years, 50.9% women)
      from the nationwide registry database were analyzed. Composite events including
      all-cause mortality and HF readmission were assessed. During the mean follow-up
      period of 1,245+/-824 days, there were 1,067 cases of composite events (49.7%).
      NT-proBNP levels were significantly higher in patients with events than those
      without in both genders (P&lt;0.001 for each). A higher NT-proBNP level was an
      independent predictor of events (highest vs. lowest tertile: hazard ratio [HR],
      1.74; 95% confidence interval [CI], 1.25-2.43; P=0.001) in men, even after
      controlling for potential confounders. However, NT-proBNP was not associated with
      the occurrence of composite events in women in the same multivariable analysis
      (P&gt;0.05). CONCLUSIONS: In patients with HF, the NT-proBNP level seems to be a
      more valuable marker in the prediction of long-term mortality and HF readmission 
      in men than in women.
FAU - Kim, Hack-Lyoung
AU  - Kim HL
AD  - Department of Internal Medicine, Seoul National University College of Medicine,
      Boramae Medical Center.
FAU - Kim, Myung-A
AU  - Kim MA
AD  - Department of Internal Medicine, Seoul National University College of Medicine,
      Boramae Medical Center.
FAU - Choi, Dong-Ju
AU  - Choi DJ
AD  - Department of Internal Medicine, Seoul National University College of Medicine,
      Bundang Hospital.
FAU - Han, Seongwoo
AU  - Han S
AD  - Department of Cardiovascular Medicine, Dongtan Sacred Heart Hospital, College of 
      Medicine, Hallym University.
FAU - Jeon, Eun-Seok
AU  - Jeon ES
AD  - Department of Internal Medicine, Sungkyunkwan University College of Medicine,
      Samsung Medical Center.
FAU - Cho, Myeong-Chan
AU  - Cho MC
AD  - Department of Internal Medicine, Chungbuk National University College of
      Medicine.
FAU - Kim, Jae-Joong
AU  - Kim JJ
AD  - Department of Internal Medicine, University of Ulsan College of Medicine, Asan
      Medical Center.
FAU - Yoo, Byung-Su
AU  - Yoo BS
AD  - Department of Internal Medicine, Yonsei University Wonju Christian Hospital.
FAU - Shin, Mi-Seung
AU  - Shin MS
AD  - Department of Internal Medicine, Gachon University Gil Hospital.
FAU - Seong, In-Whan
AU  - Seong IW
AD  - Department of Internal Medicine, Chungnam National University College of
      Medicine.
FAU - Ahn, Youngkeun
AU  - Ahn Y
AD  - Department of Internal Medicine, Chonnam National University College of Medicine.
FAU - Kang, Seok-Min
AU  - Kang SM
AD  - Department of Internal Medicine, Yonsei University Severance Hospital.
FAU - Kim, Young-Jo
AU  - Kim YJ
AD  - Department of Internal Medicine, Yeungnam University College of Medicine.
FAU - Kim, Hyung Seop
AU  - Kim HS
AD  - Department of Internal Medicine, Keimyung University College of Medicine.
FAU - Chae, Shung Chull
AU  - Chae SC
AD  - Department of Internal Medicine, Kyungpook National University College of
      Medicine.
FAU - Oh, Byung-Hee
AU  - Oh BH
AD  - Department of Internal Medicine, Seoul National University College of Medicine.
FAU - Lee, Myoung-Mook
AU  - Lee MM
AD  - Department of Internal Medicine, Sejong General Hospital.
FAU - Ryu, Kyu-Hyung
AU  - Ryu KH
AD  - Department of Cardiovascular Medicine, Dongtan Sacred Heart Hospital, College of 
      Medicine, Hallym University.
CN  - Korean Heart Failure Registry
LA  - eng
PT  - Journal Article
DEP - 20170421
PL  - Japan
TA  - Circ J
JT  - Circulation journal : official journal of the Japanese Circulation Society
JID - 101137683
OTO - NOTNLM
OT  - Gender
OT  - Heart failure
OT  - N-terminal pro-B type natriuretic peptide
OT  - Prognosis
EDAT- 2017/04/27 06:00
MHDA- 2017/04/27 06:00
CRDT- 2017/04/27 06:00
AID - 10.1253/circj.CJ-16-1345 [doi]
PST - aheadofprint
SO  - Circ J. 2017 Apr 21. doi: 10.1253/circj.CJ-16-1345.

<?xml version="1.0" encoding="UTF-8"?>
<b:Sources SelectedStyle="" xmlns:b="http://schemas.openxmlformats.org/officeDocument/2006/bibliography"  xmlns="http://schemas.openxmlformats.org/officeDocument/2006/bibliography" >
</b:Sources>