OWN - NLM
DA - 20170517
LR - 20170517
IS - 1536-5964 (Electronic)
IS - 0025-7974 (Linking)
VI - 96
IP - 20
DP - 2017 May
TI - Clinicopathological features and differential diagnosis of aggressive angiomyxoma
of the female pelvis: 5 case reports and literature review.
PG - e6820
LID - 10.1097/MD.0000000000006820 [doi]
AB - Aggressive angiomyxoma (AAM) is a rare mesenchymal tumor that usually occurs in
the pelvis and perineum of young females. AAM can simulate Bartholin's gland
cyst, abscess, lipoma, simple labial cyst, or other pelvic soft tissue tumors.
Here we present five cases of AAM with mean age of 42. The patients mainly
presented slow-growing mass in the abdomen and perineum (3 cases in the pelvis, 1
in the vulva, and 1 in the buttock). Color Doppler flow imaging revealed blood
flow for the 3 pelvic lesions. Enhanced computed tomography and magnetic
resonance imaging of the other 2 cases showed the typical "swirled" or "layered"
structure characteristic. Through the pathological examination, its positivity to
estrogen and progesterone receptors can justify enlargement and recurrence,
confirming the tumor is AAM. All 5 patients underwent local tumor resection. Two
patients recurred 8 and 15 months after surgery, respectively. The longest
follow-up was 42 months. Although few cases are reported, early recognition
demands high index of suspicion for both gynaecologists and pathologists. Wide
surgical excision with tumor free margins is the basis of curative treatment.
Adjuvant therapy may be necessary for residual or recurrent tumors. Long-term
follow-up is recommended.
FAU - Chen, Hong
AU - Chen H
AD - aDepartment of Pathology bDepartment of Ultrasonography, Beijing Chao-Yang
Hospital (Jingxi Hospital District), Capital Medical University, Beijing, China.
FAU - Zhao, Hongyan
AU - Zhao H
FAU - Xie, Yan
AU - Xie Y
FAU - Jin, Mulan
AU - Jin M
LA - eng
PT - Journal Article
PL - United States
TA - Medicine (Baltimore)
JT - Medicine
JID - 2985248R
EDAT- 2017/05/18 06:00
MHDA- 2017/05/18 06:00
CRDT- 2017/05/18 06:00
AID - 10.1097/MD.0000000000006820 [doi]
AID - 00005792-201705190-00013 [pii]
PST - ppublish
SO - Medicine (Baltimore). 2017 May;96(20):e6820. doi: 10.1097/MD.0000000000006820.