PubTransformer

A site to transform Pubmed publications into these bibliographic reference formats: ADS, BibTeX, EndNote, ISI used by the Web of Knowledge, RIS, MEDLINE, Microsoft's Word 2007 XML.

Dynamics of immunological features of oral liquid in children with chronic catarrhal gingivitis living on polluted territories with fluoride and iodine deficiency.

Abstract The aim of the study was to assess the state of oral liquid (OL) immunity in children with chronic catarrhal gingivitis (CCG) living in adverse environmental conditions. 120 children aged 7-15 residing in ecologically unfavorable areas of Lviv region were examined, while 75 children living in 'relatively clean' region were involved in the control group. Chronic catarrhal gingivitis was diagnosed according to Danilevskiy classification (1994). The level of cytokines in oral liquid of 7-years-old children living in ecologically polluted region (EPR), was (198.19±4.11)·106/l, which was 1.4 times more than in the conditionally clean region (CCR): (141.09±4.10)·106/l (p<0.01). Analysis of cytokine profile in 7-years-old from EPR showed increased levels of IL-6 proinflammatory cytokines by 11.22% (13.78±0.38 pg/ml vs 12.39±0.50 pg/ml in controls, p<0.05) and the decrease of IL-4 anti-inflammatory cytokine by 26.9% (7.12±0.62 pg/ml vs 9.74±0.58 pg/ml, p<0.01). In 12 years-old from EPR quantity of leukocytes in OL was 1.3 times higher than in controls ((246.81±4.16)·106/l vs (190.02±4.11)·106/l, p<0.01), the increase of the IL-6 content of 27.1% (p<0.01) and reduce of the IL-4 of 21.5% (p<0.05) compared to controls was also seen. At the age of 15 further increase of leucocytes in children from EPR was revealed: (297.53±4.15)·106/l, which was 1.2 times higher than in controls (p<0.01). Changes of cytokine profile in this age group were characterized by increased content of IL-6 of 26.41% (p<0.05) and IL-4 drop of 28.53% (p>0.05). Thus the age-dependent trend for the increase of leukocytes count in OL and pro-inflammatory cytokine IL-6 with the decrease of anti-inflammatory cytokine IL-4 is noted in children with CCG living in EPR.
PMID
Related Publications

Effect of cerebrolysin on remyelination processes in multiple sclerosis patients in stage of relapse regression.

Features of a necrotic and inflammatory process in different forms of nonalcoholic fatty liver disease.

Pharmacoepidemiological study of the course of influenza and other acute respiratory viral infections in risk groups.

Surgical Site Infections after Open Appendectomy and Effectiveness of Complex Approach to Their Prevention.

Role of immunological factors in the development of myopic choroidal neovascularization.

Authors

Mayor MeshTerms

Environmental Pollution

Keywords
Journal Title stomatologiia
Publication Year Start




PMID- 28514348
OWN - NLM
STAT- MEDLINE
DA  - 20170517
DCOM- 20170707
LR  - 20170707
IS  - 0039-1735 (Print)
IS  - 0039-1735 (Linking)
VI  - 96
IP  - 2
DP  - 2017
TI  - [Dynamics of immunological features of oral liquid in children with chronic
      catarrhal gingivitis living on polluted territories with fluoride and iodine
      deficiency].
PG  - 51-54
LID - 10.17116/stomat201796251-54 [doi]
AB  - The aim of the study was to assess the state of oral liquid (OL) immunity in
      children with chronic catarrhal gingivitis (CCG) living in adverse environmental 
      conditions. 120 children aged 7-15 residing in ecologically unfavorable areas of 
      Lviv region were examined, while 75 children living in 'relatively clean' region 
      were involved in the control group. Chronic catarrhal gingivitis was diagnosed
      according to Danilevskiy classification (1994). The level of cytokines in oral
      liquid of 7-years-old children living in ecologically polluted region (EPR), was 
      (198.19+/-4.11).106/l, which was 1.4 times more than in the conditionally clean
      region (CCR): (141.09+/-4.10).106/l (p&lt;0.01). Analysis of cytokine profile in
      7-years-old from EPR showed increased levels of IL-6 proinflammatory cytokines by
      11.22% (13.78+/-0.38 pg/ml vs 12.39+/-0.50 pg/ml in controls, p&lt;0.05) and the
      decrease of IL-4 anti-inflammatory cytokine by 26.9% (7.12+/-0.62 pg/ml vs
      9.74+/-0.58 pg/ml, p&lt;0.01). In 12 years-old from EPR quantity of leukocytes in OL
      was 1.3 times higher than in controls ((246.81+/-4.16).106/l vs
      (190.02+/-4.11).106/l, p&lt;0.01), the increase of the IL-6 content of 27.1%
      (p&lt;0.01) and reduce of the IL-4 of 21.5% (p&lt;0.05) compared to controls was also
      seen. At the age of 15 further increase of leucocytes in children from EPR was
      revealed: (297.53+/-4.15).106/l, which was 1.2 times higher than in controls
      (p&lt;0.01). Changes of cytokine profile in this age group were characterized by
      increased content of IL-6 of 26.41% (p&lt;0.05) and IL-4 drop of 28.53% (p&gt;0.05).
      Thus the age-dependent trend for the increase of leukocytes count in OL and
      pro-inflammatory cytokine IL-6 with the decrease of anti-inflammatory cytokine
      IL-4 is noted in children with CCG living in EPR.
FAU - Malko, N V
AU  - Malko NV
AD  - Danylo Halytsky Lviv National Medical University, Lviv, Ukraine.
FAU - Besvushko, E V
AU  - Besvushko EV
AD  - Danylo Halytsky Lviv National Medical University, Lviv, Ukraine.
LA  - rus
PT  - Journal Article
TT  - Dinamika immunologicheskikh pokazatelei rotovoi zhidkosti u detei s khronicheskim
      kataral'nym gingivitom, prozhivaiushchikh na zagriaznennykh territoriiakh s ftor-
      i ioddefitsitom.
PL  - Russia (Federation)
TA  - Stomatologiia (Mosk)
JT  - Stomatologiia
JID - 0412072
RN  - 0 (Cytokines)
RN  - 9679TC07X4 (Iodine)
RN  - Q80VPU408O (Fluorides)
SB  - D
SB  - IM
MH  - Adolescent
MH  - Child
MH  - Chronic Disease
MH  - Common Cold/*immunology
MH  - Cytokines/analysis
MH  - *Environmental Pollution
MH  - Female
MH  - Fluorides/*metabolism
MH  - Gingivitis/*immunology
MH  - Humans
MH  - Iodine/*deficiency
MH  - Leukocyte Count
MH  - Leukocytes/immunology
MH  - Leukocytosis/epidemiology/immunology
MH  - Male
MH  - Saliva/chemistry/*immunology
MH  - Ukraine/epidemiology
EDAT- 2017/05/18 06:00
MHDA- 2017/07/08 06:00
CRDT- 2017/05/18 06:00
PST - ppublish
SO  - Stomatologiia (Mosk). 2017;96(2):51-54. doi: 10.17116/stomat201796251-54.