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Applicability of antibacterial agents in chronic tonsillitis treatment.

Abstract The purpose of the present study was to evaluate the effectiveness of nitrofuranes applied for the treatment of chronic tonsillitis. A total of 92 subjects divided into three cohorts were involved in this study. Cohort 1 included 43 patients presenting with decompensated chronic tonsillitis and having pathogens in palatine tonsil lacunae. Cohort 2 was comprised of 13 patients with compensated chronic tonsillitis having pathogenic microflora of the same localization, while Cohort 3 was composed of 36 patients resembling those of cohort 1 in terms of clinical presentation, pathogen composition, and microbial spectrum. While the patients of cohort 1 and cohort 2 were treated by rinsing their tonsil lacunae with a furasol solution as a single-drug therapeutic procedure, those comprising Cohort 3 underwent treatment with furacilinum for the same purpose. The results of the study give evidence of the important advantages of furasol therapy over other modalities for the conservative treatment of chronic tonsillitis.
PMID
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Authors

Mayor MeshTerms

Staphylococcus aureus

Tonsillitis

Keywords
Journal Title vestnik otorinolaringologii
Publication Year Start




PMID- 28514366
OWN - NLM
STAT- MEDLINE
DA  - 20170517
DCOM- 20170710
LR  - 20170713
IS  - 0042-4668 (Print)
IS  - 0042-4668 (Linking)
VI  - 82
IP  - 2
DP  - 2017
TI  - [Applicability of antibacterial agents in chronic tonsillitis treatment].
PG  - 55-59
LID - 10.17116/otorino201782255-59 [doi]
AB  - The purpose of the present study was to evaluate the effectiveness of
      nitrofuranes applied for the treatment of chronic tonsillitis. A total of 92
      subjects divided into three cohorts were involved in this study. Cohort 1
      included 43 patients presenting with decompensated chronic tonsillitis and having
      pathogens in palatine tonsil lacunae. Cohort 2 was comprised of 13 patients with 
      compensated chronic tonsillitis having pathogenic microflora of the same
      localization, while Cohort 3 was composed of 36 patients resembling those of
      cohort 1 in terms of clinical presentation, pathogen composition, and microbial
      spectrum. While the patients of cohort 1 and cohort 2 were treated by rinsing
      their tonsil lacunae with a furasol solution as a single-drug therapeutic
      procedure, those comprising Cohort 3 underwent treatment with furacilinum for the
      same purpose. The results of the study give evidence of the important advantages 
      of furasol therapy over other modalities for the conservative treatment of
      chronic tonsillitis.
FAU - Vladimirova, T Yu
AU  - Vladimirova TY
AD  - Samara State Medical University, Samara, Russia, 443099.
FAU - Barishevskaya, L A
AU  - Barishevskaya LA
AD  - Samara State Medical University, Samara, Russia, 443099.
FAU - Lyamin, A V
AU  - Lyamin AV
AD  - Samara State Medical University, Samara, Russia, 443099.
FAU - Kondratenko, O V
AU  - Kondratenko OV
AD  - Samara State Medical University, Samara, Russia, 443099.
FAU - Velikanov, A K
AU  - Velikanov AK
AD  - Meditsina LLC, Samara, Russia, 443124.
LA  - rus
PT  - Journal Article
TT  - Vozmozhnosti primeneniia antibakterial'nykh sredstv pri khronicheskom tonzillite.
PL  - Russia (Federation)
TA  - Vestn Otorinolaringol
JT  - Vestnik otorinolaringologii
JID - 0416577
RN  - 0 (Anti-Bacterial Agents)
RN  - 0 (Pharmaceutical Solutions)
RN  - 5J9CPU3RE0 (Furazolidone)
RN  - X8XI70B5Z6 (Nitrofurazone)
SB  - IM
MH  - Adult
MH  - Anti-Bacterial Agents/administration & dosage
MH  - Chronic Disease
MH  - Conservative Treatment/methods
MH  - Female
MH  - Furazolidone/*administration & dosage
MH  - Humans
MH  - Male
MH  - Nitrofurazone/*administration & dosage
MH  - Pharmaceutical Solutions
MH  - Severity of Illness Index
MH  - *Staphylococcus aureus/drug effects/isolation & purification
MH  - Therapeutic Irrigation/*methods
MH  - *Tonsillitis/diagnosis/drug therapy/microbiology
MH  - Treatment Outcome
EDAT- 2017/05/18 06:00
MHDA- 2017/07/14 06:00
CRDT- 2017/05/18 06:00
PST - ppublish
SO  - Vestn Otorinolaringol. 2017;82(2):55-59. doi: 10.17116/otorino201782255-59.