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Paracoccidioidomycosis with sarcoid-like lesions:a diagnostic challenge.

Abstract Clinical presentation of paracoccidioidomycosis (PCM) can be diverse. Morphology and quantity of skin lesions depends on interactions between host immunity and fungus virulence. Diagnosis can be a challenge considering that this fungus has low virulence and some individuals have immunity to microorganism, which results in well-marked granulomas without visible microorganisms. We report herein a clinical presentation of sarcoid-like PCM, initially diagnosed as tuberculoid leprosy. This rare type of PCM is often mistaken for other types of chronic granulomatous diseases. Diagnosis was confirmed after 4 years when a special stain analysis helped in the identification of the specific etiologic agent.
PMID
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Authors

Mayor MeshTerms
Keywords
Journal Title revista da sociedade brasileira de medicina tropical
Publication Year Start




PMID- 28562770
OWN - NLM
STAT- MEDLINE
DA  - 20170531
DCOM- 20170705
LR  - 20170705
IS  - 1678-9849 (Electronic)
IS  - 0037-8682 (Linking)
VI  - 50
IP  - 2
DP  - 2017 Mar-Apr
TI  - Paracoccidioidomycosis with sarcoid-like lesions:a diagnostic challenge.
PG  - 273-276
LID - S0037-86822017000200273 [pii]
LID - 10.1590/0037-8682-0246-2016 [doi]
AB  - Clinical presentation of paracoccidioidomycosis (PCM) can be diverse. Morphology 
      and quantity of skin lesions depends on interactions between host immunity and
      fungus virulence. Diagnosis can be a challenge considering that this fungus has
      low virulence and some individuals have immunity to microorganism, which results 
      in well-marked granulomas without visible microorganisms. We report herein a
      clinical presentation of sarcoid-like PCM, initially diagnosed as tuberculoid
      leprosy. This rare type of PCM is often mistaken for other types of chronic
      granulomatous diseases. Diagnosis was confirmed after 4 years when a special
      stain analysis helped in the identification of the specific etiologic agent.
FAU - Abreu, Marilda Aparecida Milanez Morgado de
AU  - Abreu MAMM
AD  - Servico de Dermatologia, Hospital Regional de Presidente Prudente/Universidade do
      Oeste Paulista, Presidente Prudente, SP, Brasil.
FAU - Lastoria, Joel Carlos
AU  - Lastoria JC
AD  - Departamento de Dermatologia e Radioterapia, Faculdade de Medicina de Botucatu,
      Universidade Estadual Paulista, Botucatu, SP, Brasil.
FAU - Mattos, Antonio Luiz de Arruda
AU  - Mattos ALA
AD  - Laboratorio de Anatomia Patologica e Citopatologia, Presidente Prudente, SP,
      Brasil.
FAU - Alchorne, Mauricio Mota de Avelar
AU  - Alchorne MMA
AD  - Disciplina de Dermatologia, Curso de Medicina, Universidade Nove de Julho, Sao
      Paulo, SP, Brasil.
LA  - eng
PT  - Case Reports
PL  - Brazil
TA  - Rev Soc Bras Med Trop
JT  - Revista da Sociedade Brasileira de Medicina Tropical
JID - 7507456
SB  - IM
MH  - Adult
MH  - Diagnosis, Differential
MH  - Female
MH  - Humans
MH  - Leprosy, Tuberculoid/*diagnosis
MH  - Paracoccidioidomycosis/*diagnosis/drug therapy/pathology
MH  - Sarcoidosis/*diagnosis/pathology
EDAT- 2017/06/01 06:00
MHDA- 2017/07/06 06:00
CRDT- 2017/06/01 06:00
PHST- 2016/06/14 [received]
PHST- 2016/09/13 [accepted]
AID - S0037-86822017000200273 [pii]
AID - 10.1590/0037-8682-0246-2016 [doi]
PST - ppublish
SO  - Rev Soc Bras Med Trop. 2017 Mar-Apr;50(2):273-276. doi:
      10.1590/0037-8682-0246-2016.